DRSC/TRiP Functional Genomics Resources

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Protein Alignment: Unc-89 and Mylk2

Sequence 1:NP_001097440.1 Gene:Unc-89 FlyBaseID:FBgn0053519 Length:4218 Species:Drosophila melanogaster
Sequence 2:NP_476557.1 Gene:Mylk2 RGDID:620934 Length:610 Species:Rattus norvegicus

Alignment Length:302 Identity:110/303 (36%)
Similarity:169/303 (56%) Gaps:6/303 (2%)


  Fly  3190 DELGRGTQGITYHAVERSSGDNYAAKIMYGR-PELRPFMLNELEMMNTFNHKNLIRPYDAYDTDR 3253
            :.||.|..|......|||:|...|||::..: |:.:..:|.|:|:||..||:|||:.|.|.:|..
  Rat   303 EALGGGKFGAVCTCTERSTGLKLAAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQLYSAIETSH 367

  Fly  3254 SVTLIMELAAGGELVRDNLLRRDY-YTERDIAHYIRQTLWGLEHMHEMGVGHMGLTIKDLLISVV 3317
            .:.|.||...||||. :.::..|| .||.|...::||...|:..||:|.|.|:.|..:::|....
  Rat   368 EIILFMEYIEGGELF-ERIVDEDYQLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNT 431

  Fly  3318 GGDIIKVSDFGLSRKINRHNLSTLDYGMPEFVSPEVVNKEGVNFSHDMWTVGLITYVLLGGHNPF 3382
            .|.::|:.||||:|:.|.:....:::|.|||:||||||.:.::...|||::|:|||:||.|.:||
  Rat   432 TGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSLGVITYMLLSGLSPF 496

  Fly  3383 LGIDDRETLTKIREGRWDFKDEIWTHISDDGRDFISRLLLYSPEERMDVKTALKHPWFFMLDRPV 3447
            ||.||.|||..:....|.|.:|.:..:||:.:||:|.|:......||..:..|.|||...|....
  Rat   497 LGDDDTETLNNVLSANWYFDEETFEAVSDEAKDFVSNLITKDQSARMSAEQCLAHPWLNNLAEKA 561

  Fly  3448 YDHDYQIGTDRLRNYYDHFRDWYAN---ASCKNYFRRRRLSG 3486
            ...:.::.:..|...|...|.|..|   .|.:|.|::...||
  Rat   562 KRCNRRLKSQILLKKYLMKRRWKKNFIAVSARNRFKKISSSG 603

Known Domains:


GeneSequenceDomainRegion External IDIdentity
Unc-89NP_001097440.1 RhoGEF 90..260 CDD:238091
PH_unc89 275..388 CDD:270134
Atrophin-1 <493..690 CDD:331285
TonB_N 502..>596 CDD:318287
I-set 1017..1108 CDD:333254
I-set 1123..1212 CDD:254352
I-set <1236..1299 CDD:333254
I-set 1313..1403 CDD:254352
Ig_3 1406..1487 CDD:316449
I-set 1499..1595 CDD:254352
I-set 1599..1690 CDD:333254
I-set 1694..1786 CDD:254352
I-set <1836..1903 CDD:333254
I-set 1922..2005 CDD:333254
I-set 2018..2108 CDD:333254
I-set 2113..2214 CDD:333254
I-set 2220..2302 CDD:254352
I-set 2318..2408 CDD:254352
I-set 2415..2506 CDD:254352
I-set 2519..2608 CDD:254352
I-set 2615..2696 CDD:254352
I-set 2717..2805 CDD:254352
FN3 2834..2925 CDD:238020
I-set <2996..3063 CDD:333254
I-set 3067..3157 CDD:333254
PK_Unc-89_rpt1 3182..3440 CDD:271011 99/252 (39%)
I-set 3654..3744 CDD:333254
FN3 3748..3840 CDD:238020
STKc_Unc-89_rpt2 3893..4151 CDD:271014
Mylk2NP_476557.1 STKc_MLCK2 294..554 CDD:271092 99/252 (39%)
S_TKc 305..554 CDD:214567 99/250 (40%)
Calmodulin-binding. {ECO:0000250} 588..600 3/12 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E1_KOG0032
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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