DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vmat and LOC101731380

DIOPT Version :9

Sequence 1:	NP_001014525.1	Gene:	Vmat / 3346192	FlyBaseID:	FBgn0260964	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	XP_031755164.1	Gene:	LOC101731380 / 101731380	-ID:	-	Length:	414	Species:	Xenopus tropicalis

Alignment Length:	422	Identity:	212/422 - (50%)
Similarity:	279/422 - (66%)	Gaps:	26/422 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   188 NVPPPPTPCPCNKDGSEAAPLEI---STISPEE----NETYYRELEE--RHNE--LVGETVEVGL 241
            |...||.|      ||..:...:   |:.||.|    |.||....|.  ::|.  |..|.:.|||
Frog     3 NTSTPPAP------GSSFSSFLLNNESSGSPNELEDTNRTYVPNKETICKNNTSVLQEENITVGL 61

  Fly   242 LFASKAFVQLLVNPIVGPLTHRIGYSIPMFAGFVIMFLSTIIFAFGRSYLVLFVARALQGIGSSC 306
            |.||||.||:|.||||..:|:|:||.:||..||:|...|.::|||..||.:|||||:|||||:|.
Frog    62 LLASKAIVQILFNPIVSLITYRLGYELPMIFGFIITLPSILLFAFASSYSLLFVARSLQGIGTSF 126

  Fly   307 SSVSGMGMLADRFTDDKERGNAMGIALGGLALGVLIGPPFGGVMYEFVGKSAPFLILAALALGDG 371
            :|||||.:||:::|||||||.||||||||:|||::.|||||..||.||||::||||||||.|.||
Frog   127 TSVSGMAILANKYTDDKERGEAMGIALGGVALGLVAGPPFGSAMYAFVGKASPFLILAALTLLDG 191

  Fly   372 LLQLFMLQPSIQKAETEP-----PSLKSLISDPYILIAAGAITFANMGIAMLEPSLPLWMVDNMG 431
            .|:|.:|.||    :|.|     |:..:|:.||||::|||:|...||.|||.||:||:||:..|.
Frog   192 ALRLLILTPS----KTAPLTIAAPAFCALLKDPYIVLAAGSICLTNMVIAMAEPTLPVWMLGTMC 252

  Fly   432 ATRWEQGVAFLPASISYLIGTNLFGPLGHKIGRWFAACLGLIIIGGCLIFIPMATSITHLIIPNA 496
            ...|..|:.|.|||||||:.|||...|..|||||..:.||:::.|...:.:|:|.:...||.|.|
Frog   253 TPDWLLGIVFFPASISYLVCTNLLPRLSQKIGRWLCSLLGMVLAGISFLCVPLAVNFYGLITPIA 317

  Fly   497 GLGFAIGMVDSSMMPELGYLVDIRHSAVYGSVYALGDVAFCVGFAVGPALSGSLVKSIGFEWMLF 561
            ..|.:|||||.||:|.:.||||:|||:|||.|||:.|:|..:||||||.::|...|:||..|::.
Frog   318 AFGISIGMVDVSMVPLMAYLVDLRHSSVYGGVYAISDIALNLGFAVGPCVAGITAKAIGLPWLMV 382

  Fly   562 GIAILCFMYAPLLTLLKNPPTSDEKKVRMARE 593
            .||:|..||:||..||:|||...||...:.:|
Frog   383 IIAVLNIMYSPLCILLRNPPGKSEKMAILNKE 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vmat	NP_001014525.1	MFS	238..578	CDD:119392	188/344 (55%)
Vmat	NP_001014525.1	MFS_1	238..544	CDD:284993	173/310 (56%)
LOC101731380	XP_031755164.1	MFS_SLC18A1_2_VAT1_2	54..399	CDD:340942	189/348 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59108
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000700
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23506
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.020