DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trf4 and tbp

DIOPT Version :9

Sequence 1:	NP_608699.1	Gene:	Trf4 / 33452	FlyBaseID:	FBgn0031444	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_956390.1	Gene:	tbp / 368882	ZFINID:	ZDB-GENE-030616-563	Length:	302	Species:	Danio rerio

Alignment Length:	161	Identity:	34/161 - (21%)
Similarity:	68/161 - (42%)	Gaps:	1/161 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 MDFNCRFSMYELCLLLAESRFDPSSHPSVVVKITHPSAQVKIHAGGKISST-ALNADSARSGLFK 193
            ::..|:..:..:.|....:.::|....:|:::|..|.....|.:.||:..| |.:.:.:|....|
Zfish   135 VNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARK 199

  Fly   194 VIRILQDLDYKVDIMNFSKNIVNASFSMPFKIDLDLMSRRHVVEVAQNRSRRPFITYTTENLGVR 258
            ..|::|.|.:....::|....:..|..:.|.|.|:.:...|....:......|.:.|......:.
Zfish   200 YARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIV 264

  Fly   259 FAVFPTGFVLVLHSTSHCETREAIANFLPIL 289
            ..:|.:|.|::..:....|..||..|..|||
Zfish   265 LLIFVSGKVVLTGAKVRGEIYEAFENIYPIL 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trf4	NP_608699.1	TBP	128..200	CDD:278767	14/70 (20%)
		PLN00062	131..294	CDD:177693	34/160 (21%)
		TBP	213..291	CDD:278767	17/77 (22%)
tbp	NP_956390.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	50..81
		PLN00062	125..301	CDD:177693	34/161 (21%)
		TBP_eukaryotes	125..298	CDD:239952	34/161 (21%)
		1. /evidence=ECO:0000255	128..204		14/68 (21%)
		2. /evidence=ECO:0000255	218..295		15/76 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10126
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910