Protein Alignment CG4271 and KLK4

DIOPT Version :10

• Sequence 1: NP_608665.1
• Gene: CG4271 / 33410
• FlyBaseID: FBgn0031409
• Length: 242
• Species: Drosophila melanogaster
• Sequence 2: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Alignment Length: 247
• Identity: 63/247 - (25%)
• Similarity: 111/247 - (44%)
• Gaps: 28/247 - (11%)

  Fly     1 MLIGSCWVLILFARSSNGIYNGVEAKFDFWTFLASVWVSGYHECGGAVIDSRIVLTAAQCVKNKP 65
            ::.|||          :.|.||.:.......:.|::.:.....|.|.::..:.||:||.|.:|.
Human    23 LVSGSC----------SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNS- 76

  Fly    66 VKRITVRVG----TPDIYRGGRIIRVTALVVHENYKN--WDNDIALLWLEKPVL-SVRVTKIPLA 123
               .|:.:|    ..|...|.:::..:..|.|..|..  ..||:.|:.|::.|. |..:..|.:|
Human    77 ---YTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIA 138

  Fly   124 TKEPSENEYPSNAGWGEKLLESYVVTRKLQNGVTKIRPRSMCAEELVEPV-GEELLCA--FYTEN 185
            ::.|:.......:|||  ||.:..:...||.....:....:|: :|.:|: ...:.||  ...:.
Human   139 SQCPTAGNSCLVSGWG--LLANGRMPTVLQCVNVSVVSEEVCS-KLYDPLYHPSMFCAGGGQDQK 200

  Fly   186 DICPGDYGGPLVLANKVVGIAVQGHG-CGFAVLPSLYTNVFHYLEWIEENAE 236
            |.|.||.||||:....:.|:...|.. ||...:|.:|||:..:.||||:..:
Human   201 DSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4271	NP_608665.1	Tryp_SPc	19..234	CDD:238113	60/225 (27%)
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	60/225 (27%)