DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4271 and OVCH1

DIOPT Version :9

Sequence 1:	NP_608665.1	Gene:	CG4271 / 33410	FlyBaseID:	FBgn0031409	Length:	242	Species:	Drosophila melanogaster
Sequence 2:	XP_024304736.1	Gene:	OVCH1 / 341350	HGNCID:	23080	Length:	1120	Species:	Homo sapiens

Alignment Length:	241	Identity:	73/241 - (30%)
Similarity:	115/241 - (47%)	Gaps:	28/241 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 SNGIYNGVEAKFDFWTFLASVWVSGYHECGGAVIDSRIVLTAAQCV--KNKPVKRITVRVGTPDI 78
            |..|..|.||....|.:...:...|.::||||:|:...:||||.||  ||.|:. .|:..|..|
Human   607 SRRIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQLKNNPLS-WTIIAGDHD- 669

  Fly    79 YRG-----GRIIRVTALVVHENYK--NWDNDIALLWLEKPV---LSVRVTKIPLATKEPSENEYP 133
             |.     .::.|...::|||::.  ::|:||||:.|..|:   ..||...:|.:.:....:|..
Human   670 -RNLKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVCLPHSAEPLFSSEIC 733

  Fly   134 SNAGWGEKLLESYVVTRKLQNGVTKIRPRSMCAEEL--VEPVG--EELLCAFYT---ENDICPGD 191
            :..|||....:..:.:| ||.....:..|.:|....  ..|.|  |:::||.:.   |.|.|.||
Human   734 AVTGWGSISADGGLASR-LQQIQVHVLEREVCEHTYYSAHPGGITEKMICAGFAASGEKDFCQGD 797

  Fly   192 YGGPLVLANK-----VVGIAVQGHGCGFAVLPSLYTNVFHYLEWIE 232
            .|||||..::     :.||...|.||.....|.::..|..:|:||:
Human   798 SGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFARVMIFLDWIQ 843

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4271	NP_608665.1	Tryp_SPc	19..234	CDD:238113	72/238 (30%)
CG4271	NP_608665.1	Tryp_SPc	19..231	CDD:214473	70/235 (30%)
OVCH1	XP_024304736.1	Tryp_SPc	58..294	CDD:238113
		CUB	336..444	CDD:238001
		CUB	454..565	CDD:238001
		Tryp_SPc	610..845	CDD:238113	72/238 (30%)
		CUB	881..978	CDD:238001
		CUB	1017..1119	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910