DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4271 and Tmprss11d

DIOPT Version :9

Sequence 1:	NP_608665.1	Gene:	CG4271 / 33410	FlyBaseID:	FBgn0031409	Length:	242	Species:	Drosophila melanogaster
Sequence 2:	NP_663536.1	Gene:	Tmprss11d / 231382	MGIID:	2385221	Length:	417	Species:	Mus musculus

Alignment Length:	246	Identity:	79/246 - (32%)
Similarity:	112/246 - (45%)	Gaps:	33/246 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LFARSSNGIYNGVEAKFDFWTFLASVWVSGYHECGGAVIDSRIVLTAAQCVKNKPVKRI-TVRVG 74
            |...|...|..|::|:...|.:..|:.::..|.||||:|.:..|||||.|.|:.|..:. |...|
Mouse   178 LITLSEERIIGGMQAEPGDWPWQVSLQLNNVHHCGGALISNMWVLTAAHCFKSYPNPQYWTATFG 242

  Fly    75 TPDIYRGGRIIRVTALVVHENYKN--WDNDIALLWLEKPVL---SVRVTKIPLATKEPSENEYPS 134
            ...:....| :||.|::.|:.|.:  .|||||::.|::.|.   ::....:|.||    :|..|.
Mouse   243 VSTMSPRLR-VRVRAILAHDGYSSVTRDNDIAVVQLDRSVAFSRNIHRVCLPAAT----QNIIPG 302

  Fly   135 N----AGWGEKLLESYVVTRKLQNGVTKIRPRSMCAEELVEPVGEE------LLCAFYTEN--DI 187
            :    .|||........||...|..|     |.:.:||...|.|..      :|||.....  |.
Mouse   303 SVAYVTGWGSLTYGGNAVTNLRQGEV-----RIISSEECNTPAGYSGSVLPGMLCAGMRSGAVDA 362

  Fly   188 CPGDYGGPLVLANK-----VVGIAVQGHGCGFAVLPSLYTNVFHYLEWIEE 233
            |.||.|||||..:.     ||||...|:.||....|.:||.|..|..||.:
Mouse   363 CQGDSGGPLVQEDSRRLWFVVGIVSWGYQCGLPNKPGVYTRVTAYRNWIRQ 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4271	NP_608665.1	Tryp_SPc	19..234	CDD:238113	77/238 (32%)
CG4271	NP_608665.1	Tryp_SPc	19..231	CDD:214473	75/234 (32%)
Tmprss11d	NP_663536.1	SEA	48..140	CDD:279699
		Tryp_SPc	185..411	CDD:214473	75/235 (32%)
		Tryp_SPc	186..414	CDD:238113	77/238 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910