DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31668 and CG31262

DIOPT Version :9

Sequence 1:	NP_001097055.2	Gene:	CG31668 / 33395	FlyBaseID:	FBgn0051668	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_001138069.2	Gene:	CG31262 / 318649	FlyBaseID:	FBgn0051262	Length:	579	Species:	Drosophila melanogaster

Alignment Length:	582	Identity:	329/582 - (56%)
Similarity:	445/582 - (76%)	Gaps:	9/582 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDTYRFGTVDYAVFLGVTILSIAIGLYFGFIRKSRNGPKTTTPTNEAPERRHQNFGSKKMNDYMM 65
            ||.||||||||.|.:.:|:||...|:|||.::|.....|:.:..|     |..||||:|:::|:|
  Fly     1 MDNYRFGTVDYLVLVAMTLLSTGTGIYFGALKKKHKNKKSVSEDN-----RRTNFGSEKIDEYLM 60

  Fly    66 GSRNLRVFPVGMSLIASCISAVAIIGTPSEIYNYGTQYCFIVIALVLQGLAVSYIYLPVFSALQV 130
            ||||::|.||.::|    ....:|||||||||:|||||..|::|::|||:|.||:||||:||||:
  Fly    61 GSRNMKVIPVSITL----YRVTSIIGTPSEIYHYGTQYYLIIVAIILQGIAFSYVYLPVYSALQI 121

  Fly   131 TSSYEYLEMRFHSAIRSIVSIIFILDVVLYLPFLAYLPALALNQVSGMNMYLIEAFIIVICVIYT 195
            .|:||||.:||:|.||:..|.:::..::.||||:.|:|||:|:||||:|.:||...||:.||.||
  Fly   122 GSAYEYLGLRFNSIIRTTASFMYVFGILTYLPFIVYVPALSLSQVSGLNTHLIGLVIILACVTYT 186

  Fly   196 VLGGLKAVVHTDIWQVVIMFASVLTIVVLATCYIDDQADFLEGLVRGGRLIFSETNPSPFARHTV 260
            .:||||||||||:|||.:||.|::.:..||..|.:......:...:||||:.:.|||||:.||||
  Fly   187 FMGGLKAVVHTDVWQVAVMFLSLVAVAFLAIYYSNGLVAVFDDAEQGGRLMLANTNPSPYVRHTV 251

  Fly   261 WSVVIGNTFYWTSLNAVHQTVVHRYMSLPTLKMARASIAFLVVGAAFFISLLCYLGLLIFHAYRD 325
            |||:||...:|||:||..|.:|.||||||:||.:|.:.....:|.:.||:|.|::|||:|..|:|
  Fly   252 WSVLIGGFSFWTSVNAGGQHMVQRYMSLPSLKKSRQASFIFTIGVSIFIALCCFMGLLLFSKYKD 316

  Fly   326 CDPLSAGLIMNDDQLVPLFVVNSLGHVYGMPGLFIAGIFGASLSSLSVYLNSTSLVILQDLVRGC 390
            |||.|||:|:|||||:|||||.|:||:||||||||||||||.|||||...|:.|:|.|:|:|||.
  Fly   317 CDPRSAGMILNDDQLLPLFVVQSVGHIYGMPGLFIAGIFGAGLSSLSSCFNTVSMVFLEDIVRGF 381

  Fly   391 FKMELGEWASTIVVKGSIVVLGLLAFAMVFVLEKVSGVLSISVSLAAIAASSTFGIFTVGMLVPW 455
            ||||..|..|||::|..|:..|:|||.:||:|:.:.|:||:..|:::|.|.::||:||:|||.||
  Fly   382 FKMEPSERQSTILIKTCIIFQGILAFLIVFLLQHLRGILSVCNSISSITAGTSFGVFTLGMLFPW 446

  Fly   456 ANTVGTAVGGIASVLLTGWISFGSQFAAASGQLGSQRLPVSVEGCLANASVAENAWVAEEEVFPL 520
            |||:||||||::||||.||||||||.|||||||.|..|||||:.|:.|.::.|:.||.:::||||
  Fly   447 ANTIGTAVGGLSSVLLAGWISFGSQIAAASGQLKSGMLPVSVKECVGNVTLPEDPWVDQDQVFPL 511

  Fly   521 YRLSYHWISPIGVLTVVVVGSLVSLVTKPTDIKSLDSDLITPVIHRFLPKECFEQGNAEENS 582
            |||||||:|||||:|.||||:||||:|||.|||:|.::||:||||||||:|||...|..|.:
  Fly   512 YRLSYHWVSPIGVVTAVVVGALVSLITKPADIKTLHAELISPVIHRFLPRECFRGRNLNERT 573

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31668	NP_001097055.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	287/521 (55%)
CG31262	NP_001138069.2	SLC5sbd_NIS-SMVT	9..522	CDD:271383	287/521 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45473049
Domainoid	1	1.000	544	1.000	Domainoid score	I933
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	716	1.000	Inparanoid score	I1768
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243316at2759
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
	10	9.900