Protein Alignment aop and Ets1

DIOPT Version :10

• Sequence 1: NP_523455.2
• Gene: aop / 33392
• FlyBaseID: FBgn0000097
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_001359463.1
• Gene: Ets1 / 23871
• MGIID: 95455
• Length: 484
• Species: Mus musculus
• Alignment Length: 468
• Identity: 112/468 - (23%)
• Similarity: 168/468 - (35%)
• Gaps: 138/468 - (29%)

  Fly    40 KTQLPPSLPSDPRLWSREDVLVFLRFCVREFDLPKLDFDLFQMNGKALCLLTRADFGHRCPG-AG 103
            |.|....:|.|||.|:...|..::.:.|.||.|..:||..|.|:|.|||.|.:..|....|. .|
Mouse   102 KEQQRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFCMSGAALCALGKECFLELAPDFVG 166

  Fly   104 DVL--H-NVLQMLIIESHMMQWHLPNSPVT-PTSRYPLS---PHSH--PPTPTWPPLNAPPENSP 159
            |:|  | .:||...::.:.:....|..|.: .||.|.:|   .|:.  ||:    ..:.|...:.
Mouse   167 DILWEHLEILQKEDVKPYQVNGANPTYPESCYTSDYFISYGIEHAQCVPPS----EFSEPSFITE 227

  Fly   160 FHSSAHSLAGHHFMAPN------SVTLSPPPSVDSQASSPPQAPY----------QNGGATGAAP 208
            .:.:.|.::....::..      ||.|..|...|:.     |..|          .|.....|:.
Mouse   228 SYQTLHPISSEELLSLKYENDYPSVILQDPLQTDTL-----QTDYFAIKQEVLTPDNMCLGRASR 287

  Fly   209 GSAGG--SAPAAGGATNTSNPTSSSASSTGSNGSQPNIMPMKGISSASSNHSDSEEEYSETSGGV 271
            |..||  |..:.....:....|.|.:|.:..|..|          ...|..|...|:|
Mouse   288 GKLGGQDSFESVESYDSCDRLTQSWSSQSSFNSLQ----------RVPSYDSFDYEDY------- 335

  Fly   272 SKMPPAPLSYSTASPPGTPILKDIKPNWTQQLTNSFVNSWSQQQQQQQQQQAAAVAAVAAQAQQH 336
                  |.:.....|.||  .||            :|...:...:.:....|||:|....
Mouse   336 ------PAALPNHKPKGT--FKD------------YVRDRADLNKDKPVIPAAALAGYTG----- 375

  Fly   337 QLQQQQQQQQLPQKLTLDNTAGPVVTPAGGSISAPTTPSYMYKAKREFFPENSEPNTNGRLLWDF 401
                                :||:                                    .||.|
Mouse   376 --------------------SGPI------------------------------------QLWQF 384

  Fly   402 LQQLLNDRNQKYSDLIAWKCRDTGVFKIVDPAGLAKLWGIQKNHLSMNYDKMSRALRYYYRVNIL 466
            |.:||.|::  ....|:| ..|...||:.||..:|:.||.:||...|||:|:||.|||||..||:
Mouse   385 LLELLTDKS--CQSFISW-TGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNII 446

  Fly   467 RKVQGERHCYQFL 479
            .|..|:|:.|:|:
Mouse   447 HKTAGKRYVYRFV 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aop	NP_523455.2	SAM_PNT-Tel_Yan	49..116	CDD:176085	26/70 (37%)
		ETS	395..482	CDD:197710	37/85 (44%)
Ets1	NP_001359463.1	SAM_PNT-ETS-1	95..182	CDD:176092	29/79 (37%)
		Ets1_N_flank	191..378	CDD:466113	44/257 (17%)
		ETS	378..462	CDD:197710	38/121 (31%)