Protein Alignment aop and Fli1

DIOPT Version :10

• Sequence 1: NP_523455.2
• Gene: aop / 33392
• FlyBaseID: FBgn0000097
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_032052.1
• Gene: Fli1 / 14247
• MGIID: 95554
• Length: 452
• Species: Mus musculus
• Alignment Length: 591
• Identity: 119/591 - (20%)
• Similarity: 186/591 - (31%)
• Gaps: 267/591 - (45%)

  Fly    29 PPAPSSQLAELKTQLPPSLPSDPRLWSREDVLVFLRFCVREFDLPKLDFDLFQ-MNGKALCLLTR 92
            ||.|:....|.:.    .:|:||.||::|.|..:|.:.::|:.|.::|...|| |:||.||.:.:
Mouse   112 PPPPNMTTNERRV----IVPADPTLWTQEHVRQWLEWAIKEYGLMEIDTSFFQNMDGKELCKMNK 172

  Fly    93 ADFGHRCPGA--GDVLHNVLQMLIIESHMMQWHLPNSPVTPTSRYPLSPHSHPPTPTWPPLNAPP 155
            .|| .|...|  .:||.:.|..| .||.::.:
Mouse   173 EDF-LRATSAYNTEVLLSHLSYL-RESSLLAY--------------------------------- 202

  Fly   156 ENSPFHSSAHSLAGHHFMAPNSVTLSPPPSVDSQASSPPQAPYQNGGATGAAPGSAGGSAPAAGG 220
             |:..|:...|          .:.:...||.||                            ...|
Mouse   203 -NTTSHTDQSS----------RLNVKEDPSYDS----------------------------VRRG 228

  Fly   221 ATNTSNPTSSSASSTGSNGSQPNIMPMKGISSASSNHSDSEEEYSETSGGVSKMPPAPLSYSTAS 285
            |.|.:       .::|.|.|     |:.|              .|:|.|..::..|.|..|....
Mouse   229 AWNNN-------MNSGLNKS-----PLLG--------------GSQTMGKNTEQRPQPDPYQILG 267

  Fly   286 PPGTPILKDIKPNWTQQLTNSFVNSWSQQQQQQQQQQAAAVAAVAAQAQQHQLQQQQQQQQLPQK 350
            |
Mouse   268 P---------------------------------------------------------------- 268

  Fly   351 LTLDNTAGPVVTPAGGSISAPTTPSYMYKAKREFFPENSEPNTNGRLLWDFLQQLLNDRNQKYSD 415
                 |:..:..|..|.|.                            ||.||.:||:|  ...:.
Mouse   269 -----TSSRLANPGSGQIQ----------------------------LWQFLLELLSD--SANAS 298

  Fly   416 LIAWKCRDTGVFKIVDPAGLAKLWGIQKNHLSMNYDKMSRALRYYYRVNILRKVQGERHCYQF-- 478
            .|.|: ...|.||:.||..:|:.||.:|:..:|||||:||||||||..||:.||.|:|:.|:|
Mouse   299 CITWE-GTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDF 362

  Fly   479 -------LRNPTELKNIKNISLLRQSTPANGNGGSPSMPQGSSQAPGSPAGQNWNPQQQSQQQQQ 536
                   ..:|||....|                             .|:..::.|...:.||:.
Mouse   363 HGIAQALQPHPTETSMYK-----------------------------YPSDISYMPSYHAHQQKV 398

  Fly   537 S--PQRPASRNGPMSLPAVAAVAAAAAAAYGPPPTSPLFMHAINGAFHYLSAAAAGPPPNSPALN 599
            :  |..|:      |:|..::....||:.|...||:.::.:.              ..|..|..:
Mouse   399 NFVPSHPS------SMPVTSSSFFGAASQYWTSPTAGIYPNP--------------SVPRHPNTH 443

  Fly   600 TPSAVG 605
            .||.:|
Mouse   444 VPSHLG 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aop	NP_523455.2	SAM_PNT-Tel_Yan	49..116	CDD:176085	25/69 (36%)
		ETS	395..482	CDD:197710	39/95 (41%)
Fli1	NP_032052.1	SAM_PNT-FLI-1	114..204	CDD:188883	30/129 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	236..260		9/42 (21%)
		ETS	280..363	CDD:197710	40/113 (35%)