Protein Alignment Wdr62 and si:ch73-174h16.5

DIOPT Version :10

• Sequence 1: NP_001259886.1
• Gene: Wdr62 / 33367
• FlyBaseID: FBgn0031374
• Length: 2397
• Species: Drosophila melanogaster
• Sequence 2: XP_021333610.2
• Gene: si:ch73-174h16.5 / 100003472
• ZFINID: ZDB-GENE-160728-123
• Length: 1084
• Species: Danio rerio
• Alignment Length: 750
• Identity: 138/750 - (18%)
• Similarity: 253/750 - (33%)
• Gaps: 257/750 - (34%)

  Fly   135 IKVWELETPNGSLEHCSGGSVVAEFVDHKYAVTCVAFSPTGKYLVS-------------VGSQHD 186
            |:||.   |:..|:.|        ||.|...||.:|..|....|:|             || .|.
Zfish    93 IRVWR---PDWELQMC--------FVGHTALVTSLALCPVSGLLLSSSLDGTVRCWSPEVG-DHV 145

  Fly   187 MIVNVFDWRANLKMASNKISSKVAAVCFSEDGSYFVTVGNRHVKYW------YLEGGRKYKDPIP 245
            .||::          .|:.|..: .:..|:..:.|.:.....|.:|      ||.....:.:.:|
Zfish   146 QIVSI----------PNECSPPL-IMGGSDSAANFFSYSTNSVDFWTFNCLYYLHCRLDWVNRLP 199

  Fly   246 LMGRSAILGDLRDNDFCA-VACGKGICAESTYAITRQGHLVEFSSRRLLDKWVQCRTTNANCICV 309
            :   ..|........|.| |.|..|....:..|..:...|..|.::..    |.|    |:| ||
Zfish   200 I---CQISTPPNPPSFQACVVCTHGNSNITVVAADKDAVLTRFQTKGK----VVC----ADC-CV 252

  Fly   310 NERFILVGCAESIIRIFNSATLEYVTTLPRTHYLGVDVAQGIQINHIMSVPQQAKF--PDCIAMV 372
            .::.:||...:.::.|  ::||....|: :..:.|::..:|      .|...:||.  ..|:.:.
Zfish   253 PKKILLVLTEDGVVTI--ASTLTSPITI-QDEWRGIERWEG------PSGQTEAKIGTVSCMVLY 308

  Fly   373 FD----------EQRS----KVSCVYNDHSLYIWDLRDISRVGKSHSFLYHSTCIWGVETVPYNV 423
            :|          .||:    |:..:::::...:    .:..:|...|.|..::......|..:|.
Zfish   309 YDITDKEWESLQTQRAHKPKKIRLLHDENRFLV----ILGHLGGYVSVLNMNSAKVQFRTSAHNN 369

  Fly   424 EREPS-QTLPEECF-VTCSSDDTIRVWGLDGCTNNDIYRRNIYSKELLKIVYSDDELQFIKDQGS 486
            :...| |..|:..| :|...|..:.||.:..|           :|:.|.:.:|
Zfish   370 KNINSMQAYPDSGFLLTAGEDKAVLVWRVFPC-----------AKQCLSLHFS------------ 411

  Fly   487 SLFDKAGNSSYDGRNGVRCIKISPELQHLASGDRCGNIRVYSLVNLRLLTTIEAHESEVLCL--- 548
                            |.|  ..|.:             :.:|:..:|:..:|..|::...|
Zfish   412 ----------------VLC--DHPPV-------------LLALLGTQLILALEDPENKTDSLVQH 445

  Fly   549 ------EYSNEKIERK--------------LLASASRDRLIHVFDVAQNYLLLQTLDDHSSSITS 593
                  .|..:..||.              :.||:|:|..:.::|:..  .||:.|:
Zfish   446 SLDSQTRYDQQPSERHHKKITGLCACCQLGVFASSSQDETVRIWDMKN--CLLRILE-------- 500

  Fly   594 IKFVGAGLNFQ---MISCGADKSIMFRSFQGNIFMRGTNT-----SGKTTLYDMEVD------SN 644
                   ||.:   :..||....::. ...|::: |..||     ..:|...|.:.:      ::
Zfish   501 -------LNAEPECLAYCGESGDLLL-GITGDLY-RIPNTHLLPPDCRTQKCDPDTELPKSWNTS 556

  Fly   645 AKHILTACQDRNVRVYGTQNAKQTK-----TFKGSHSDEGSLIKLSLDPSGIYVATSCTDKTLAV 704
            .|..:.:|  ..:|..|.::...||     .|...|.|..||.|..::         |..|.:|.
Zfish   557 LKSRMESC--CFIRKDGPKSLDYTKDPDFGVFMARHKDLESLRKGEIE---------CRTKKIAT 610

  Fly   705 ----YDYYSNECMARMYGHSELVTGLKFTNDCRHLISASGDGCIFIWQVPHDMIVTMQARMSQQR 765
                .:.:|| .::::|         :...|.|               :|.||..........:
Zfish   611 VQTKQEAFSN-YLSKIY---------RQPLDIR---------------IPEDMFEICSLLFPPK- 649

  Fly   766 LRSGHAPLPRPLAPISPPDGIVLESPTSEIEQPQL 800
                |..|| ||.|          ...|::::.||
Zfish   650 ----HPELP-PLPP----------KRQSDLDEVQL 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wdr62	NP_001259886.1	WD40	<73..236	CDD:441893	28/119 (24%)
		WD40 repeat	73..107	CDD:293791
		WD40 repeat	113..161	CDD:293791	7/25 (28%)
		WD40	156..573	CDD:475233	86/477 (18%)
		WD40 repeat	167..207	CDD:293791	11/52 (21%)
		WD40 repeat	209..285	CDD:293791	14/82 (17%)
		WD40 repeat	303..338	CDD:293791	10/34 (29%)
		WD40 repeat	353..407	CDD:293791	10/69 (14%)
		WD40	<437..750	CDD:441893	57/358 (16%)
		WD40 repeat	505..540	CDD:293791	4/34 (12%)
		WD40 repeat	546..586	CDD:293791	12/62 (19%)
		WD40 repeat	591..631	CDD:293791	8/47 (17%)
		WD40 repeat	637..672	CDD:293791	7/45 (16%)
		WD40 repeat	679..717	CDD:293791	8/41 (20%)
		WD40 repeat	723..749	CDD:293791	2/25 (8%)
si:ch73-174h16.5	XP_021333610.2	None