Protein Alignment CG31663 and Mfsd6

DIOPT Version :8

• Sequence 1: NP_001259884.1
• Gene: CG31663 / 33363
• FlyBaseID: FBgn0051663
• Length: 966
• Species: Drosophila melanogaster
• Sequence 2: NP_001100381.1
• Gene: Mfsd6 / 301388
• RGDID: 1562317
• Length: 794
• Species: Rattus norvegicus
• Alignment Length: 918
• Identity: 185/919 (20%)
• Similarity: 326/919 (35%)
• Gaps: 278/919 (30%)

  Fly    10 ATDPVVSEKVELSRFGEFCQRRGINPNLIMLKITLFVMYGATSSLLPYLTIHMQSIGLTVEEIAI 74
            :|:.....:.|:....:.|.:  ||.:|::.|:..|..|.|..||.|.|.::.:.:|::..:..:
  Rat    44 STETSAIPEEEIDWIEKHCVK--INNDLLISKVFYFFFYSAYGSLYPLLPVYYKQLGMSPSQSGL 106

  Fly    75 IYLALPFTTFLSPPITGFLVDKFGKYKPVVVMSLLLNAIFHHSLLFIPQQE---IPGVVPSAFVL 136
            :.....|..|.|.|..|.:.|:|.|.|.|::.|||...:|:..:.|:....   ||.:.|:|
  Rat   107 LVGIRYFIEFCSAPFWGVVADRFKKGKIVLLFSLLCWVLFNLGIGFVKPATLRCIPKIPPTA--- 168

  Fly   137 RHPDSGDIEVWWSPCPSRECPEEPELELAVHQCVDYCLMQEQVNPQLYTNTPAYDVRPAATTSTT 201
             ||                                             ||
  Rat   169 -HP---------------------------------------------TN--------------- 172

  Fly   202 QRSQLTATTARTTTMEPSSESSSSPAPTTSTTTSPASSLPALFATQTRSRYQEVLNMSSTMFPPM 266
                    .:...|:.|.:                 ||..|.|.|..:|..:..|..|:|
  Rat   173 --------VSHPVTILPMN-----------------SSTVAFFTTPPKSLEKRSLLFSAT----- 207

  Fly   267 SQLKDALEEGVEPGQSSSAELSAMSMQGLNLTNSSQKKLLWSSWVHSDNDDATYFMLQMHPDLAD 331
                       ||                   |.|...||           :|...|...|.|..
  Rat   208 -----------EP-------------------NISNIDLL-----------STALTLTTEPTLRP 231

  Fly   332 PTEQLGMEIEQDANETVTDILQRFGHDYLVRGNINLTDMDDLDLRCGGLVRRTNMTNIASGAVEC 396
            .||.:        ...|||::       |....:.|..       .|.:.|.|.:..:.:
  Rat   232 QTEGI--------THHVTDLI-------LNTSTVTLPP-------TGNVTRETTIAVVTT----- 269

  Fly   397 MMQRCTFTLNAPEICPPDYKETDEIIFWVYFLLRFLATTMLSAGVTIMDPIALTMIEKYGGDFGR 461
                 |.:|.:.::.....::..|.||.|..::..:.....::.|||:|.:.|..:.|:...:|.
  Rat   270 -----TKSLPSDQVTLVYDQQEVEAIFLVILVVVIIGEFFSASSVTIVDTVTLQYLGKHRDRYGL 329

  Fly   462 ERLFSSIGMAIFSPITGIMIDYSS-----RGLG-----YTDYSAAFYTYDVLLVISTMSVLMMP- 515
            :|::.|:|..:.....||.|||:.     .|.|     |.:|...|..:.||:   ||::::..
  Rat   330 QRMWGSLGWGLAMLSVGIGIDYTHIDVLIDGKGCKPPEYRNYQIVFIVFGVLM---TMALIVATQ 391

  Fly   516 -------------LGEKLPADNVFRD--------------------LWNLLKMPHVIAFICFLFV 547
                         .|:::....|.||                    .|:|:|:...:.:...|||
  Rat   392 FRFRYNHFNNSDGKGKEMEIPQVERDNSTESSEETPTAATHSQAFNFWDLIKLLCSVQYGSVLFV 456

  Fly   548 ---LGNFWGFIESFLFLYLKELGAPNYLLGITITVGTVSSIPFLYGAEKITRIFGHVNLIIIAFF 609
               :|..:||:.:||:.:|::|.....|.|:...:..||.:...:.:.|:..:.||:.::.|...
  Rat   457 AWFMGFGYGFVFTFLYWHLEDLNGTTTLFGVCSVLSHVSELTAYFFSHKLIELIGHIRVLYIGLA 521

  Fly   610 SHAGRLVGYSFIETAWWCFPFEAMESLSCHLMWVAAATYCSILAPKSLLATLIGVLGMAHFSLGR 674
            .:..|.:..|::|.||...|.|.::.::...:|.|..:|.|...|..|..:..|:|...|..|||
  Rat   522 CNTARYIYISYLENAWTVLPMEVLQGVTHAAIWAACISYLSAAVPPELRTSAQGILQGLHLGLGR 586

  Fly   675 GSGSFTGGLLIGQFGTRDAFRYMGLLAVVGGIAYGLLHLIWL----------------------- 716
            |.|:..||:|:..||....||.:|:..:|..:.:.|:.  ||
  Rat   587 GCGAMIGGVLVNYFGAAATFRGIGMACLVILLLFALIQ--WLAVPDEEEDKTMLAERIPVPSSPV 649

  Fly   717 --RKFDHTTEESEEEVEAVEA----------GETEKLTEPATKEQGTSMSLERLSLMIKYNQIGS 769
              ...|...:::|:.:..:||          .|.|.:.:||   .|.|.| ..::.:....|:..
  Rat   650 PIATIDLVQQQTEDVMPHIEARLPPKKTKHQEEQEDVNKPA---WGVSSS-PWVTFVYALYQVKE 710

  Fly   770 LSSLPRGSRADIHDHLSVRRSSYNVESLRGVPRHGNIGSASKVDILRSALEINHKSSNNSMLSKA 834
            |..|.|.|||.            .::.|:|:..:..:..|...   :.|....|..|..:.||..
  Rat   711 LMRLTRDSRAS------------EIQPLQGIHENRQVSPAGGA---QCAPHETHSDSPRNQLSPD 760

  Fly   835 DNKTSNQS 842
            ...:..||
  Rat   761 TAASQMQS 768

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31663	NP_001259884.1	MFS_1_like	36..111	CDD:289593	23/75 (31%)
		MFS	<423..711	CDD:119392	82/335 (24%)
		MFS_1	<423..678	CDD:284993	72/302 (24%)
Mfsd6	NP_001100381.1	MFS_1_like	68..143	CDD:289593	23/75 (31%)
		MFS_1	<77..169	CDD:284993	27/96 (28%)
		TMIE	366..>395	CDD:292657	7/32 (22%)
		MFS_1	453..>651	CDD:284993	51/200 (26%)
		MFS	453..>623	CDD:119392	49/170 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG3762
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR16172
Phylome	1	0.910		0.667	Consistency score
TreeFam	0	0.000	Not matched by this tool.
	3	2.910