Protein Alignment CG31663 and MFSD6L

DIOPT Version :10

• Sequence 1: NP_722738.1
• Gene: CG31663 / 33363
• FlyBaseID: FBgn0051663
• Length: 966
• Species: Drosophila melanogaster
• Sequence 2: NP_689812.3
• Gene: MFSD6L / 162387
• HGNCID: 26656
• Length: 586
• Species: Homo sapiens
• Alignment Length: 736
• Identity: 133/736 - (18%)
• Similarity: 243/736 - (33%)
• Gaps: 236/736 - (32%)

  Fly    56 PYLTIHMQSIGLTVEEIAIIYLALPFTTFLSPPITGFLVDKFGKYKPVVVMSLL--LNAIFHHSL 118
            |:||::::.:||....:..:............|:..||...:.|.:.:::.|||  :.|    ||
Human    32 PFLTLYLRQLGLAAPWVGTLMGTKHLIAAFWAPVCAFLAKSYRKRRALLIGSLLGSVGA----SL 92

  Fly   119 LFIPQQEIPGVVPSAFVLRHPDSGDIEVWWSPCPSRECPEEPELELAVHQCVDYCLMQEQVNPQL 183
            |.:       :||..      |...:..   ||..
Human    93 LMV-------LVPPV------DKNRVHF---PCNG------------------------------ 111

  Fly   184 YTNTPAYDVRPAATTSTTQRSQLTATTARTTTMEPSSESSSSPAPTTSTTTSPASSLPALFATQT 248
                      .:..|||.....:|.....|:..|   .:||.||..|:....|....|
Human   112 ----------SSGLTSTDALPGVTLPVNITSAQE---SASSHPAKRTAEVEMPGFRNP------- 156

  Fly   249 RSRYQEVLNMSSTMFPPMSQLKDALEEGVEPGQSSSAELS------AMSMQGLNLTNSSQKKLLW 307
                                          ||:|......      |.|::|...|:.:....:.
Human   157 ------------------------------PGESDRETFRDLHVYLAPSVEGARTTSQALLHPVT 191

  Fly   308 SSWVHSDNDDATYFMLQMHPDLADPTEQLGMEIEQDANETVTDIL---QRFGHDYLVRGNINLTD 369
            |.             |:.||          .|:..:..:|...:|   :..|:...:.|......
Human   192 SG-------------LKDHP----------WEVTFEVVKTALPLLPGGKGPGNPANLSGTKGKAW 233

  Fly   370 MDDLDLRCGGLVRRTNMTNIASGAVECMMQRCTFTLNAP--EICPPDYKETDEII--------FW 424
            ..||.|..   :|||.:.::.|.|...:       |.||  ::......|..:.:        .|
Human   234 AFDLSLEA---LRRTFILSLGSVAFWEL-------LTAPLEQVADDSLYEFLDFVDATDRYRSLW 288

  Fly   425 VYFLLRFLATTMLSAGVTIMDPIALTMIEKYGGDFGRERLFSSIGMAIFSPITGIMIDYSSRGLG 489
            |:.||.      :||||     ..:|                    |:...:...::....||:.
Human   289 VWRLLG------MSAGV-----CGIT--------------------ALVGQLDCFLMTSGPRGVV 322

  Fly   490 YTDYSAAFYTYDVLLVISTMSVLMMPLGEKLPADNVFRDLWNLLKM-------PHVIAFICFLFV 547
            :      ||.|.   |:||:: |::.:...:|....:...:..:|.       ||:|.......:
Human   323 H------FYGYS---VVSTLA-LLVSIAFPIPICQQWEPSYKRVKALSIVGGDPHLILLASTTVL 377

  Fly   548 LGNFWGFIESFLFLYLKELGAPNYLLGITITVGTVSSI---PFLYGAEKITRIFGHVNLIIIAFF 609
            :|.....:::|||.::|:.|:...::|.::.:..:..|   ||   ...:.|......|:.:...
Human   378 VGAIVSTVQNFLFWHMKDHGSGELVMGFSVALSLLGEILLHPF---KATLLRKLSRTGLVGLGLS 439

  Fly   610 SHAGRLVGYSFIETAWWCFPFEAMESLSCH-LMWVAAATYCSILAPKSLLATLIGVLGMAHF-SL 672
            ..||:|:.|||:.:.|...|.:.:.::|.. |.|...|:...:..|:  :...:..|...|| ..
Human   440 CLAGQLLYYSFLWSWWSVLPIQILSAISNRALWWAVGASVEDLATPR--MERALSALFRGHFYGS 502

  Fly   673 GRGSGSFTGGLLIGQFGTRDAFRYMGLLAVVGGIAYGLLHLIWL-------RKFDHTTEESEEEV 730
            |...|||.||.::.:|..  |..|......:         |:||       |:.....:....::
Human   503 GCSLGSFVGGFVVMRFSL--AVLYQACCVAL---------LLWLALLLSIQRRLPRERKIKYSKL 556

  Fly   731 EAVEAGETEKLTEPATKEQGT 751
            .::|..:|      :..||||
Human   557 LSMEVSDT------SDSEQGT 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31663	NP_722738.1	MFS	37..>122	CDD:475125	16/67 (24%)
		MFS_MFSD6	<420..713	CDD:340893	61/312 (20%)
MFSD6L	NP_689812.3	MFS_MFSD6L	16..529	CDD:341032	123/677 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	133..160		10/66 (15%)