Protein Alignment CG17646 and Abcg4

DIOPT Version :10

• Sequence 1: NP_608618.1
• Gene: CG17646 / 33354
• FlyBaseID: FBgn0264494
• Length: 766
• Species: Drosophila melanogaster
• Sequence 2: NP_001100286.2
• Gene: Abcg4 / 300664
• RGDID: 1305840
• Length: 646
• Species: Rattus norvegicus
• Alignment Length: 734
• Identity: 260/734 - (35%)
• Similarity: 374/734 - (50%)
• Gaps: 113/734 - (15%)

  Fly    42 GC-LGINCCTTAASSELSIDETSSTSSRGSCELTSKVTNDLNGFQSPNYHQAVAHANFDHC---D 102
            || ||......|.:.|...:....|:.      ..||.|.:...|           .|.|.   .
  Rat    10 GCGLGPGAVAMAVALEDGAEPPVLTTH------LKKVENHITEAQ-----------RFSHLPKRS 57

  Fly   103 PVDIQFADVRYTVKKFSFPERKFVTKEILHGLNGSFRSGELTAIMGPSGAGKSTLLNVMSGFCST 167
            .|||:|.::.|:|::... .||...|.:|..|:|.|...||..|||||||||||.:|:::|:..:
  Rat    58 AVDIEFVELSYSVREGPC-WRKRGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRES 121

  Fly   168 GVSGDIRVNRKPMAPSSERFRQMLCYIHQDDLLRPQLLVGEIMLLAAHLKLGFKVTKAYKMDLIK 232
            |:.|.|.||.:|.  ....||:|.|||.|||:|.|.|.|.|.|:::|:|||..|  :..|.:|:.
  Rat   122 GMKGQILVNGRPR--DLRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEK--QEVKKELVT 182

  Fly   233 HILSLLGLDHRYNVPTGKLSGGQKKRLAIALELISNPPVLYLDEPTTGLDSSSCSSCVALLKKLA 297
            .||:.|||....:..|..|||||:|||||||||::||||::.||||:||||:||...|:|:|.||
  Rat   183 EILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLA 247

  Fly   298 SQGHTIVCTIHQPSALIFEMFDKLYTVVDGHCMYQGPVRELVPFLADQQLVCPSYHNPADYLLEV 362
            ..|.|::||||||||.:||||||||.:..|.|:::|.|..|:|:|....|.||:||||||:::||
  Rat   248 HGGRTVICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPADFIIEV 312

  Fly   363 AVGEHQRDLNELIHAANKKYYEDVDRHRYMSSDDMARLVESIKENMGGKAVVKTSEALAAFAAAQ 427
            |.||: .|||.::..|                                     ....|...|..
  Rat   313 ASGEY-GDLNPMLFRA-------------------------------------VQNGLCTMAEK- 338

  Fly   428 FSSFDYVKPSPQELALEEIKALSGGPESADPDLLEKNLRPQPQPLAKAGELARPP--NAIRSASF 490
                   |.||                       |||..|...|..       ||  :.|.|.:|
  Rat   339 -------KSSP-----------------------EKNEVPAHCPTC-------PPELDPIESHTF 366

  Fly   491 ----LMQYVLLMQRILICAKRNYFLLLARIFSHIFIGVVFGYLYMNVGNNAQSVLGNYVYLYGST 551
                |.|:.:|.:|..:...|:..|...|..||:.|||:.|.||:::|::|..|..|..:|:.|.
  Rat   367 ATSTLTQFCILFRRTFLSILRDTVLTHLRFMSHVLIGVLIGLLYLHIGDDASKVFNNTGFLFFSM 431

  Fly   552 LLLVYTGKMAVVLTFPLEIDMLTREHFNRWYKLGPYFLSLISFEIPFQSLCTAMYIIISVHLTGN 616
            |.|::...|..|||||||:.:..|||.|.||.|..|:|:....::|||.:|..:|..|...:||.
  Rat   432 LFLMFAALMPTVLTFPLEMAVFMREHLNYWYSLKAYYLAKTMADVPFQVVCPVVYCSIVYWMTGQ 496

  Fly   617 DATDSFRIYYFMLLGIMASLSAQAWGFFVG-ATLPTKLAVFLGPILAVMFSVF-GFCTRYIDITP 679
            .|..| |...|..|.|..:|.||:.|..:| |:...::|.|:||:.|:...:| ||...:..|..
  Rat   497 PAETS-RFLLFSALSIATALVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFKTIPT 560

  Fly   680 LFRWMWHLSYFRAGFHGALNAIYGMDRPFLECPETAMYCHFRSPKVFLKYMMISDVHMSDCLILM 744
            ..:|..:|||.|.||.|.:..||||:|..|.|.|.  :|.||.|::.|..:.:.:..:....:::
  Rat   561 YLQWSSYLSYVRYGFEGLILTIYGMERGHLTCLED--HCPFRDPQIILHELDVEEAKLYMDFLVL 623

  Fly   745 GIVIGVMHVLTLITLWHKL 763
            ||....:.:|..:.|.:::
  Rat   624 GIFFLALRLLAYLVLRYRV 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	3a01204	123..765	CDD:273361	241/649 (37%)
Abcg4	NP_001100286.2	3a01204	44..646	CDD:273361	250/694 (36%)