Protein Alignment CG17646 and abcg8

DIOPT Version :10

• Sequence 1: NP_608618.1
• Gene: CG17646 / 33354
• FlyBaseID: FBgn0264494
• Length: 766
• Species: Drosophila melanogaster
• Sequence 2: XP_031758486.1
• Gene: abcg8 / 100498405
• XenbaseID: XB-GENE-981625
• Length: 682
• Species: Xenopus tropicalis
• Alignment Length: 652
• Identity: 161/652 - (24%)
• Similarity: 295/652 - (45%)
• Gaps: 96/652 - (14%)

  Fly   131 LHGLNGSFRSGELTAIMGPSGAGKSTLLNVMSGFCSTG--VSGDIRVNRKPMAPSSERFRQMLCY 193
            :..:|....||::.|::|.:|.||::||::::.....|  .||.|.:|.|  ..:..|.::.:.:
 Frog    90 MKNINVKVTSGQMLAVIGNTGCGKTSLLDIITCKDEGGKIKSGQILINGK--VSTKHRVKKCVAH 152

  Fly   194 IHQDDLLRPQLLVGEIMLLAAHLKLGFKVTKAYKMDLIKHILSLLGLDHRYNVPTGK-----LSG 253
            :.|||.|.|.|.|.|.:...|.|:|....::..:...::.:::.|.|....|...|.     :||
 Frog   153 VRQDDQLLPHLTVRETLTFIAKLRLPKSYSEEQRRRQVEDVIAELRLRQCANTKVGNTYTRGVSG 217

  Fly   254 GQKKRLAIALELISNPPVLYLDEPTTGLDSSSCSSCVALLKKLASQGHTIVCTIHQPSALIFEMF 318
            |:::|::|.::|:.||.:|.|||||:||||.:..:.|..|.:||.....::.:||||.:.||::|
 Frog   218 GERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVITLSRLARGNRLVLLSIHQPRSDIFQLF 282

  Fly   319 DKLYTVVDGHCMYQGPVRELVPFLADQQLVCPSYHNPADYLLEVAVGEHQRDLNELIHAANKKYY 383
            |.:..:..|..:|.|..:::|.:.:.....||.|.||||:.:         ||..:.....::..
 Frog   283 DLVLLLSSGATIYSGTAKDMVEYFSSIGYPCPRYSNPADFYV---------DLTSIDQRNKERET 338

  Fly   384 EDVDRHRYMSSDDMARLV-ESIKENMGGKAVVKTSEALAAFAAAQFSSFDYVKPSPQELALEEIK 447
            |.::|.|     .:|.:. |.:|:                       |.|::...|.| |.:.|.
 Frog   339 ESLERTR-----SLAEIFWEKVKD-----------------------SDDFLWKPPGE-ANKNIT 374

  Fly   448 ALSGG---PESADPDLLEKNLRPQPQPLAKAGELARPPNAIRSASFLMQYVLLMQRILICAKRNY 509
            ..:..   |.||.    ||.::      .|..::.:.|..      |.|:.:|::|.:....|:.
 Frog   375 PTNTSINLPVSAH----EKAIK------IKNSDMDQLPRG------LHQFSVLLRRHVSNDLRDL 423

  Fly   510 FLLLARIFSHIFIGVVFGYLYMNVGNNAQSVLGNYVYLYGSTLLLVYTGKMAVVLTFPLEIDMLT 574
            ..||...|..:.:.::.|:||...|||..|:..:...|:....|..:...:.||.....|..||.
 Frog   424 STLLIHGFEALVMALLIGFLYYGQGNNQLSIQDSIALLFMKGSLTPFAVVLDVVAKCHSERAMLY 488

  Fly   575 REHFNRWYKLGPYFLSLISFEIPFQSLCTAMYIIISVHLTG-NDATDSFRIYYFMLLGIMASLSA 638
            .:..:..|.:.|||.:.:..|:|........|.:....|.. |...:.|.:.:.:||.|:  ..:
 Frog   489 HDLEDGLYSVTPYFFAKVIGELPEHFAFVIFYGVPIYWLANLNPHPECFLLNFALLLLIV--YCS 551

  Fly   639 QAWGFFVGATLPT-KLAVFL-GPILAVMFSVFGFCTRYIDITPLFRWMWHLSYFRAGFHGALNAI 701
            :|...::.|.||| :::.|| ..|....:...||..|..::..:..|:.::|:.|.||.|.:...
 Frog   552 RAMALWMSALLPTLQMSSFLSNAIFTSSYLTGGFIIRLENLWTVPYWISYVSFLRWGFEGLMQVQ 616

  Fly   702 YGMDRPF--------LECPETAMYCHFRSPKVFLKYMMISDVH--MSDCLILMGIVIG--VMHVL 754
            : .|..:        :..|.||:..:           |..|.|  .:..|:|:||:.|  |::.|
 Frog   617 F-TDLSYKVPVGNITITIPGTAIISN-----------MEMDSHPLYASYLVLIGIIAGFLVLYYL 669

  Fly   755 TL 756
            :|
 Frog   670 SL 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	3a01204	123..765	CDD:273361	161/652 (25%)
abcg8	XP_031758486.1	3a01204	61..672	CDD:273361	161/652 (25%)