Protein Alignment nis and qrich2

DIOPT Version :10

• Sequence 1: NP_608605.1
• Gene: nis / 33337
• FlyBaseID: FBgn0031347
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: XP_002935980.3
• Gene: qrich2 / 100497746
• XenbaseID: XB-GENE-1003760
• Length: 941
• Species: Xenopus tropicalis
• Alignment Length: 654
• Identity: 143/654 - (21%)
• Similarity: 236/654 - (36%)
• Gaps: 187/654 - (28%)

  Fly    58 SSLLTLGNTSKFRLFAGADAEEG-------AAAEPAAEPPAEEAEAPP-----------APVEEP 104
            :.|.|||...:       |.|.|       |.|..:.:..|..||.||           .|.|||
 Frog   278 TDLPTLGKVVR-------DLETGWTQTSDPAYATVSTQAVACSAEVPPQGHVPQVTVVSPPCEEP 335

  Fly   105 PAADPAPEPAPEPAPEPAAEEP----APAEPVP----EEAAPAEAAAPSPEPVGSNHEPTPSATP 161
            ..|:...:.|.:|...||::..    :|...|.    :|........||..| |....|..:..|
 Frog   336 SLAEGPSQAALDPLLGPASQTEGGALSPQTAVSFQTFQEGLQFSTGLPSTPP-GGPVPPCSAVNP 399

  Fly   162 APEEHPPSEPEADTSKAPMDVPAEAKG-----EELAPQASR---VSSRSSGRDKSHSQ--TDGSL 216
            :...|||..|...   .|...||:..|     |:|..|.:.   :::..|.:..|.||  |..::
 Frog   400 SVSTHPPGSPMVG---PPSTTPAQLPGVTFVPEQLTDQPNNPAAITTEISSQLASTSQPITGATI 461

  Fly   217 ----TNNLLRLERRLSKIELQKEQATMEVQQFVSNLTSQLKITMEQVNNMTHLLIDRKPNPQRFR 277
                :|...|..:|.:.        |:|..:.:..||.:..:..|:|..:.....||
 Frog   462 PVVPSNGNSRASQRYAD--------TVEALRKMGALTDKYSVLRERVEALLRNKADR-------- 510

  Fly   278 LLRHIAKQLRVLMVTTGDEVSVSWSSGDIVDGVEEEGLSE--------EEVPVESSAPTEVEKPE 334
                  .:|:.|:...| :::|...|.::.      ||.|        :|:           |.|
 Frog   511 ------SELKALLEGRG-QLTVPDGSNNVA------GLQEKMNVARFMQEI-----------KAE 551

  Fly   335 EEEELELEQPLCYSPEKMLTELLDLKSQFCALTNKVNELAAALLKQDSQRLMDQMKDLSETVRDI 399
            .|::.||              :.||:::......:...|..:|.::..|
 Frog   552 REKDGEL--------------IGDLQTKLLTFQGECERLEKSLAEEQQQ---------------- 586

  Fly   400 KLYMASNKEATNGMMTRLNDCVYQIQVLKKSASHLDEVKIDKTEVELLLAEKVDFQQLATKVSLE 464
                 :.|               .|.||.:....|:|.|.||..:||.:..|.|.|.|..|||..
 Frog   587 -----TQK---------------HIDVLYEKLDKLEEKKADKEHLELEIDVKADKQALDGKVSRA 631

  Fly   465 QLEEYKARLEQMFCEVRHIVSLNEKNVLQIIDNLRMTL--GIDALELSLKDFREMIERRVQIIAE 527
            |.:....:|..:..|:...||..|::..::::.|.|.:  .:|.:||.  .|::.:|.|.:.|..
 Frog   632 QFDATAEQLNSIVHELLGRVSGQEQDWQKVLEKLNMEMQNKLDRMELD--PFKKKLEERWKSIRR 694

  Fly   528 ALQKYMEMTNDDCAAAAGRVKVMQDLACLACDTTCVMRTVERS-------KVPSLPNAKGSTGLG 585
            .||:.......| .||..|.:::....||:||     |.::.|       .:|::|.........
 Frog   695 QLQERSPQYEAD-EAAGIRKQLISHFHCLSCD-----RPLDISMPGPPILTIPNVPGLPVHRSTR 753

  Fly   586 PIVTYELGQIRKSGIMGYYRKDEFPHSTSAWTKGASGVPMVKC--TPRHAGGSHT---THTADEH 645
            |...|||.|||:     ::..|.           |..:....|  :.|:.|||||   :|.....
 Frog   754 PQSVYELEQIRQ-----HFCSDR-----------AQELADYSCMSSMRNCGGSHTLTYSHRRFPK 802

  Fly   646 MQKV 649
            :|.:
 Frog   803 LQNI 806

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nis	NP_608605.1	DUF4795	379..562	CDD:464990	44/184 (24%)
qrich2	XP_002935980.3	COG4913	<70..>246	CDD:443941
		PHA02682	<318..521	CDD:177464	48/228 (21%)
		DUF4795	552..728	CDD:464990	52/233 (22%)