Protein Alignment CG4887 and Rbm10

DIOPT Version :10

• Sequence 1: NP_608582.2
• Gene: CG4887 / 33304
• FlyBaseID: FBgn0031318
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: XP_063136351.1
• Gene: Rbm10 / 64510
• RGDID: 631366
• Length: 930
• Species: Rattus norvegicus
• Alignment Length: 1119
• Identity: 331/1119 - (29%)
• Similarity: 473/1119 - (42%)
• Gaps: 321/1119 - (28%)

  Fly    14 ENEGGRGSDYYRSRPGSRYSRSRSRSRERNRSHGGIRHRNSRSRSRDRDRSPVFRNDQHRGGRGG 78
            |..||||     .|.| ||.     :.:|::..||      .:||||.
  Rat     4 ERRGGRG-----DRTG-RYG-----ATDRSQDDGG------ENRSRDH----------------- 34

  Fly    79 AGNGDPDLYHSLINDDYRDQDERNYNSRSNFENRQFRRHDSFDRRHRDRDGESDRELNDYEYEQR 143
                           ||||.|.|:|                 .|.:..::|:       :||:..
  Rat    35 ---------------DYRDMDYRSY-----------------PREYGSQEGK-------HEYDDS 60

  Fly   144 SRDLDSRDRSSTDRDWYHNRSRSREHSRPWNRNNNHDDRSRSNERNTRHRDHRMYNGGGSNHNRD 208
            |.:..:.|                          :::....|..:..|.|.||....|.....||
  Rat    61 SEEQSAED--------------------------SYEASPGSETQRRRRRRHRHSPTGPPGFPRD 99

  Fly   209 ---RDRDRDREQ-DRERDRDRDRDRERRGSSDYDSDEGHMRRNKYRSTTEALNIIIIFGLTKEMT 269
               ||:|...|| :.|.:.|.:.:.|.:.|                      ||:::..|.:..|
  Rat   100 GDYRDQDYRTEQGEEEEEEDEEEEEEEKAS----------------------NIVMLRMLPQAAT 142

  Fly   270 RADIMSELIKVNMEPACIRIIRKQGTDSSRGIAFVEFNTVEEAKQWMDITQGVLKLNDERVSMRY 334
            ..||..:|....::...:|::|.:.:..|||.|||||:.:::|.:||:..|..|.:..::|||.|
  Rat   143 EDDIRGQLQSHGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRWMEANQHSLNILGQKVSMHY 207

  Fly   335 SH---KRIQDWNCNKCGVCNFKFRFYCFVCKTSREDSETTFSSG--------------------- 375
            |.   |..:||.||||||.|||.|..||.|...:.::|.....|
  Rat   208 SDPKPKINEDWLCNKCGVQNFKRREKCFKCGVPKSEAEQKLPLGTRLDQQALPLGGRELSQGLLP 272

  Fly   376 ----------------SEGVDEVSTILTKKIMLRNLDALTNEEAVLTALQLHLKDLSKTVSKVLI 424
                            |:|.:..|......|:||||:..:..:::|.||..:.. ||.  |.|.:
  Rat   273 LPQPYQAQGVLTSQALSQGSEPSSENANDTIILRNLNPHSTMDSILGALAPYAV-LSS--SNVRV 334

  Fly   425 SRDSLTQASRGICYLHFDTLVDSMNVHNALTALDPPLTLDDRVVAITYCIDLEEQQALPKNPKEL 489
            .:|..||.:||..::...|:|::..:...|.||.||||:|.:.:.:.:....:...|
  Rat   335 IKDKQTQLNRGFAFIQLSTIVEAAQLLQILQALHPPLTIDGKTINVEFAKGSKRDMA-------- 391

  Fly   490 AVKDSTVNSGNIS---------AVSPSGLGGNYTLADVPRLAEYSASLYASNPAEHAYYVQ---- 541
            :.:.|.:|:.:::         |:|.:..||..|.| .|.          ..|.:::||.|
  Rat   392 SNEGSRINAASVASTAIAAAQWAISQASQGGESTWA-APE----------EPPVDYSYYQQDEGY 445

  Fly   542 --------YYTEYYTADINKNNRDSHLTEA---NSGA-----------AVALSAIQRKQ------ 578
                    .|...|.    ||.:...:|..   .|||           :|:|.|..|.|
  Rat   446 GSSQGTDSLYAHGYL----KNTKGPGMTGTKGDTSGAGPETSLEGGTDSVSLQAFSRAQPGAAPG 506

  Fly   579 -----KKMSSIETTITAAATAAAQAAAQVKATL--------AAQVASAPKGNDG-KIYPTPDVTQ 629
                 .:.||.:.|.|.:.:....:.|.:|:.|        |...|::|...:. ..||.|||:.
  Rat   507 LYQQSAEGSSGQGTATNSQSYTIMSPAVLKSELQSPTHPSSALPPATSPTAPESYSQYPVPDVST 571

  Fly   630 YQYDETSGYYYDSTTGLYYNAHSQYYYNNETGAYLYWDQRRSTYVLATPASTQAALQEVLADAEQ 694
            ||||||||||||..|||||:.:||||||.::..|||||..|.||:   ||..|:      ||..:
  Rat   572 YQYDETSGYYYDPQTGLYYDPNSQYYYNAQSQQYLYWDGERRTYI---PALEQS------ADGHK 627

  Fly   695 KGEEESKKAKEKEGGNKHDKVKVAKKIVKDMEKWAKQLNQKKDYTAVATPQPILA------NEVA 753
            .....||:.|||:  .|| |.|.|::|.||||:||:.||::|: ....:.|||.|      .|.|
  Rat   628 DTGASSKEGKEKK--EKH-KTKTAQQIAKDMERWARSLNKQKE-NFKNSFQPISALRDDERRESA 688

  Fly   754 TTSRGNQGGYADVGFSILEKK----ER-------GKL-NDYAPNPTVGPMNKLVNAYGGTSDSEE 806
            |         ||.|::|||||    ||       .|| :|..|:|..|    ||.||.|.|||||
  Rat   689 T---------ADAGYAILEKKGALAERQHTSMDLPKLASDDRPSPPRG----LVAAYSGESDSEE 740

  Fly   807 DNAASSQNTQSSAVVSGGGGAEESDYVDFHKLTCLLCKRAFQSLEILQKHLKMSTLHKENL---- 867
            :.             ..||...|....|:.||.||||:|.|.|.|.|.:|.::|.|||:||
  Rat   741 EQ-------------ERGGPEREEKLTDWQKLACLLCRRQFPSKEALIRHQQLSGLHKQNLEIHR 792

  Fly   868 -AKLNQNTSSSIE----EALAYRDRAKERRLKYGESDPPPPNRSRERFEQEIKTLQSRQKQSTSA 927
             |.|::|...::|    |.:.|||||.|||.|||..:||.|.|   |....|.|.....:|.|..
  Rat   793 RAHLSENELEALEKNDMEQMKYRDRAAERREKYGIPEPPEPKR---RKYGGISTASVDFEQPTRD 854

  Fly   928 TPAMPISSSNVGSRLLQKMGWSEGQGLGRKNQGRTQIIEADGRSNYVGLGNKSGQ--MIPGNDYK 990
                .:.|.|:|||:||.|||.||.|||||.||....|||..|....|||.:...  :.....||
  Rat   855 ----GLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTRVRGSGLGARGSSYGVTSTESYK 915

  Fly   991 SYIKKMMKQRYENA 1004
            ..:.|.|..|:..|
  Rat   916 ETLHKTMVTRFNEA 929

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4887	NP_608582.2	U2AF_lg	93..>193	CDD:273727	15/99 (15%)
		RRM_SF	255..335	CDD:473069	25/79 (32%)
		ZnF_RBZ	341..364	CDD:197784	15/22 (68%)
		RanBP2-type Zn finger	342..361	CDD:275377	13/18 (72%)
		RRM1_RRM2_RBM5_like	387..473	CDD:409752	27/85 (32%)
		OCRE_RBM5_like	623..678	CDD:293881	35/54 (65%)
		OCRE repeat 1	628..635	CDD:293881	4/6 (67%)
		OCRE repeat 2	636..643	CDD:293881	6/6 (100%)
		OCRE repeat 3	644..651	CDD:293881	5/6 (83%)
		OCRE repeat 4	652..659	CDD:293881	6/6 (100%)
		OCRE repeat 5	661..668	CDD:293881	4/6 (67%)
		G-patch	935..979	CDD:396249	26/43 (60%)
Rbm10	XP_063136351.1	None