Protein Alignment CG4887 and GPATCH2L

DIOPT Version :10

• Sequence 1: NP_608582.2
• Gene: CG4887 / 33304
• FlyBaseID: FBgn0031318
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: XP_016876916.1
• Gene: GPATCH2L / 55668
• HGNCID: 20210
• Length: 495
• Species: Homo sapiens
• Alignment Length: 501
• Identity: 90/501 - (17%)
• Similarity: 162/501 - (32%)
• Gaps: 132/501 - (26%)

  Fly   217 QDRERDRDRDRDRERRGSSDYDSDEGHMRRNK--YRSTTEALNIIIIFGLTKE------MTRADI 273
            |.|.:.|.| |.|:||      ||..|:..:.  |...:|:    .:...||:      :|....
Human    47 QQRRQLRKR-RGRKRR------SDFTHLAEHTCCYSEASES----SLDEATKDCREVAPVTNFSD 100

  Fly   274 MSELIKVNMEPACIRIIRKQGTDSSRGIAFVEFNTVEEAKQWMDITQGVLKLNDERVSMRYSHKR 338
            ..:.:.....||...|::.:........:|.|.......::    .:.|.::..|..:......:
Human   101 SDDTMVAKRHPALNAIVKSKQHSWHESDSFTENAPCRPLRR----RRKVKRVTSEVAASLQQKLK 161

  Fly   339 IQDWNCNKCGVCNFKFRFYCFVCKTSREDSETTFSSGSEGVDEVS---TILTKKIMLRNLDALTN 400
            :.||:..:  .|.||   .....:.||....|.::|...|:.|.:   |.|:|......::..|:
Human   162 VSDWSYER--GCRFK---SAKKQRLSRWKENTPWTSSGHGLCESAENRTFLSKTGRKERMECETD 221

  Fly   401 EEAVLTALQLHLKDLSKTVSKV---LISRDSLTQAS--------RGICYLHFDTLVDSMNVHNAL 454
            |:...:...:...:.|...|..   |.:.|...|..        .|.|       |....|.|.|
Human   222 EQKQGSDENMSECETSSVCSSSDTGLFTNDEGRQGDDEQSDWFYEGEC-------VPGFTVPNLL 279

  Fly   455 TALDPPLTLDDRVVAITYCIDLEEQQA-----------LPKNP---------------------- 486
            ....|           .:|.::|...:           ||..|
Human   280 PKWAP-----------DHCSEVERMDSGLDKFSDSTFLLPSRPAQRGYHTRLNRLPGAAARCLRK 333

  Fly   487 --KELAVKDSTVNSGNISAVS-----PSGLGGNYTLA-DVPRLAEYSASLYASNPAEHAYYVQYY 543
              :.|..|::::|:.....:|     |.....|..|| |.|.:   ||..:..||         .
Human   334 GRRRLVGKETSINTLGTERISHIISDPRQKEKNKALASDFPHI---SACAHEFNP---------L 386

  Fly   544 TEYYTADINKNNRDSHLTEANSGAAVA--------LSAIQRKQKKM--------SSIETTITAAA 592
            :..|:.|:..:......:.|:..|..|        ...|:||:|.:        |::........
Human   387 SPLYSLDVLADASHRRCSPAHCSARQANVHWGPPCSRDIKRKRKPVATASLSSPSAVHMDAVEPT 451

  Fly   593 TAAAQAAAQVKATLAAQVASAPKGNDGKIYPTPDVTQYQYDETSGY 638
            |.|:||.....:....:.::|.|..|.   .|....:...:::.||
Human   452 TPASQAPKSPSSEWLVRTSAAEKATDA---TTATFFKMPQEKSPGY 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4887	NP_608582.2	U2AF_lg	93..>193	CDD:273727
		RRM_SF	255..335	CDD:473069	10/85 (12%)
		ZnF_RBZ	341..364	CDD:197784	5/22 (23%)
		RanBP2-type Zn finger	342..361	CDD:275377	4/18 (22%)
		RRM1_RRM2_RBM5_like	387..473	CDD:409752	15/96 (16%)
		OCRE_RBM5_like	623..678	CDD:293881	3/16 (19%)
		OCRE repeat 1	628..635	CDD:293881	0/6 (0%)
		OCRE repeat 2	636..643	CDD:293881	2/3 (67%)
		OCRE repeat 3	644..651	CDD:293881
		OCRE repeat 4	652..659	CDD:293881
		OCRE repeat 5	661..668	CDD:293881
		G-patch	935..979	CDD:396249
GPATCH2L	XP_016876916.1	None