Protein Alignment Charon and Asb10

DIOPT Version :10

• Sequence 1: NP_608581.2
• Gene: Charon / 33303
• FlyBaseID: FBgn0031317
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001102686.1
• Gene: Asb10 / 499972
• RGDID: 1562922
• Length: 465
• Species: Rattus norvegicus
• Alignment Length: 498
• Identity: 99/498 - (19%)
• Similarity: 147/498 - (29%)
• Gaps: 192/498 - (38%)

  Fly   111 WDTEETHMPGITNNSCEAKGNRHSHMTSSSSEPIKPPVDPTKVPKKRGRKRNTCVPQVVKRSAAE 175
            |..||....|      |.:|||:|.......:|.:.|
  Rat     3 WSPEECRDQG------EPQGNRYSLCARLVEKPDRAP---------------------------- 33

  Fly   176 MALKEREEKQLTPVITKRKK------------RDVTQAQNFESYQITNKTPVRRNSTLSDISFNS 228
               :|..|..|.|:|.::..            .||.......|...|...|        |.:|::
  Rat    34 ---EENPEPGLGPIIVRKASGPALAFWQAVLVGDVGSVSQILSDSSTGLAP--------DSTFDT 87

  Fly   229 DELTRVENFISGNTEDRIIRIMANEFRKS-----HIMSEEGLLPIHEEILHGDVYGVKRQIFVCC 288
            .:..|..::   ....|.:|:.:..|.:.     |:.:..|    |.|:|         |:.:..
  Rat    88 SDPERWRDY---RFNIRALRLWSLTFEEELTTPLHVAASRG----HTEVL---------QLLLRR 136

  Fly   289 HAKMD--------INELLTRDGEDCLELAL-------TNDTD-------------TEIVSLILDA 325
            .||.|        ::|........|:.:.|       |.|.|             .|.|.|:|..
  Rat   137 RAKPDSAPGGRTALHEACAAGHAACVHVLLVAGADPNTPDQDGKRPLHLCRGPGILECVELLLKF 201

  Fly   326 RMMTDHLYEN-SNTALHLAV-INHINIESIRL----------------LLRRID----------- 361
            ....|...|: ..|.||:|. :.|:.:..:.|                ||...|
  Rat   202 GAQVDGRSEDEEETPLHVAARLGHVELADLLLRWGACPHVRNSEGWTPLLTACDARCQSPVDAEA 266

  Fly   362 -------LNSLLLT--------NDDGYTVLHLAVRNNQFLVVEAILD---SIDERELG------- 401
                   |.||||:        |.|....||||.|:....||:.:|.   |.:..:.|
  Rat   267 TANRCFQLCSLLLSVGADADAANQDKQRPLHLACRHGHSAVVQLLLSCGVSANAMDYGGHTPLHC 331

  Fly   402 -------------ETVYRRTLEAANPNEWDEKGFAKYYDRACERLELNKTLLKNRAHKRDVINAS 453
                         |.:.|..|.......| .....|..||.|......:.|:..   .|.|....
  Rat   332 ALLGPTTALAHSPEHIVRDLLNYGAVRVW-PGALPKVLDRWCMSPRTIEVLMNT---YRVVQLPE 392

  Fly   454 EARGGNPP------------LFYAVEGEQ--EHLC-YFLLAHL 481
            ||:|..||            ||..|:..:  :||| :.|..||
  Rat   393 EAKGLVPPEILQKHCGFYSSLFALVKQPRSLQHLCRWALRTHL 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Charon	NP_608581.2	ANKYR	290..513	CDD:440430	66/302 (22%)
		ANK repeat	301..333	CDD:293786	10/51 (20%)
		ANK repeat	335..369	CDD:293786	14/77 (18%)
		ANK repeat	371..455	CDD:293786	22/106 (21%)
		ANK repeat	457..488	CDD:293786	12/40 (30%)
Asb10	NP_001102686.1	ANKYR	<112..312	CDD:440430	44/212 (21%)
		ANK repeat	116..143	CDD:293786	9/39 (23%)
		ANK repeat	146..176	CDD:293786	4/29 (14%)
		ANK repeat	178..210	CDD:293786	6/31 (19%)
		ANK repeat	212..243	CDD:293786	6/30 (20%)
		ANK repeat	245..289	CDD:293786	8/43 (19%)
		ANK repeat	291..322	CDD:293786	10/30 (33%)
		Ank_2	296..>359	CDD:463710	13/62 (21%)
		SOCS	419..458	CDD:239641	6/17 (35%)