Protein Alignment drongo and Arfgap2

DIOPT Version :10

• Sequence 1: NP_001162848.1
• Gene: drongo / 33263
• FlyBaseID: FBgn0020304
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_001159496.1
• Gene: Arfgap2 / 77038
• MGIID: 1924288
• Length: 534
• Species: Mus musculus
• Alignment Length: 691
• Identity: 131/691 - (18%)
• Similarity: 225/691 - (32%)
• Gaps: 280/691 - (40%)

  Fly    26 SNRQCFDCGQKGPTYVNMTIGSFVCTRCSGVLRGLTPPHRVKSISMATFTQDEID---------- 80
            :|:.|||||.|.|::.::|.|.|:|..||||       ||...:.::.....|:|
Mouse    22 TNKACFDCGAKSPSWASITYGVFLCIDCSGV-------HRSLGVHLSFIRSTELDSNWSWLQLRC 79

  Fly    81 -----------FLRSHG---NELCAKTWLGLWDPKRAVHQQEQRELMMDKYERK--RYYLEPASP 129
                       |.|.||   |:  |.|                      ||..:  :.|.|....
Mouse    80 MQVGGNANATAFFRQHGCMAND--ANT----------------------KYTSRAAQMYREKIRQ 120

  Fly   130 LKSLANA-------VNLKSSAPATNHTQNGHQNGYASIHLTPPA--AQRTSANGLQKVANSSSNS 185
            |.|.|..       ::..:|||  :|:.....:.:.:.|...||  ...|..:|.|:.|..|.
Mouse   121 LGSAALTRHGTDLWIDSMNSAP--SHSPEKKDSDFFTEHTQAPAWDTAATDPSGTQQPALPSE-- 181

  Fly   186 SGKTSSSISRPHYNHQNNSQNNNHDAFGLG--GGLSS--LNSAGSTSTGALSDT------SSCAS 240
                |||:::|       .|..|.|..|..  ..|.|  |::.|.:.|..|..:      .:.|.
Mouse   182 ----SSSLAQP-------EQGPNTDLLGTSPQASLESMYLSAKGPSCTRELKSSIIGKKKPAAAK 235

  Fly   241 NGFGADCDFVADFGSANIFDATSARSTGSPAVSSVSSVGSSNGYAKVQPIRAAHLQQQQQLQQQL 305
            .|.||                  .:..|:..||:.|               ...:::|.|:.::|
Mouse   236 KGLGA------------------KKGLGAQKVSNQS---------------FTEIERQAQVAEKL 267

  Fly   306 HQQQLLNGNGHQGTENFADFDHAPIYNAVAPPTFNDWISDWSRRGFHDPFDDCDDSPPGARPPAP 370
            .:||
Mouse   268 REQQ------------------------------------------------------------- 271

  Fly   371 APAPAQVPAVSSPLPTVREEPELAWNFWEDEMRIEAQEKES-----QTKQPELGYSFSISTTTPL 430
             .|.|:..|..|.:.::|    ||:    .|::|:.:::|.     :.|:.|......:...:..
Mouse   272 -AADAKKQAEESMVASMR----LAY----QELQIDRKKEEKKLQNLEGKKREQAERLGMGLVSRS 327

  Fly   431 SPSNPFLPYLVSEEQHRNHPEKPSFSYSLFSSISNSSQEDQADDHEMNVLNANFHDFFTWSA--- 492
            |.|:..|..:...||     |.|      .|:.|:.||.|.            |.|..|:::
Mouse   328 SISHSVLSEMQMIEQ-----ETP------LSAKSSRSQLDL------------FDDVGTFASGPP 369

  Fly   493 -----PLQNGHTTSPPKGGNAA--MAPSEDR-----YAALKDLDEQLRELKASESATETPTPTSG 545
                 |...|.|.......:||  |...|::     .::::.:.|:      :.|..|..|.:||
Mouse   370 KYKDNPFSLGETFGSRWDSDAAWGMDRVEEKEPEVTISSIRPISER------TASRREVETRSSG 428

  Fly   546 --NVQATDAFGGALNNNPNPFKGQQ----------QQQLS------------------------- 573
              :.:|...|.||...:.:.|.|::          .||||
Mouse   429 LESSEARQKFAGAKAISSDMFFGREVDSEYEARSRLQQLSGSSAISSSDLFGNMDGAHGGGTVSL 493

  Fly   574 SHVVNPFQQQQQQQHQQNLYGQLTLIPNAYGSSSQQQMGHH 614
            .:|:......|.:|..:::.|::.::.|...:|.|.:.|.:
Mouse   494 GNVLPTADIAQFKQGVKSVAGKMAVLANGVMNSLQDRYGSY 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drongo	NP_001162848.1	ArfGap_AGFG	15..123	CDD:350067	29/122 (24%)
Arfgap2	NP_001159496.1	PLN03114	3..484	CDD:178661	123/639 (19%)
		ArfGap_ArfGap2	5..124	CDD:350086	32/132 (24%)
		YqiK	<256..>318	CDD:441869	17/131 (13%)