Protein Alignment: GABA-B-R3 and gpr156

• Sequence 1: NP_001245826.1
• Gene: GABA-B-R3
• FlyBaseID: FBgn0031275
• Length: 1305
• Species: Drosophila melanogaster
• Sequence 2: XP_004919836.1
• Gene: gpr156
• XenbaseID: XB-GENE-962217
• Length: 792
• Species: Xenopus tropicalis
• Alignment Length: 660
• Identity: 148/661 (22%)
• Similarity: 268/661 (41%)
• Gaps: 113/661 (17%)

  Fly   628 LSSVGIALAIAFLAFNLHFRKLKAIKLSSPKLSNITAVGCIFVYATVILLGLDHSTLPSAEDSFA 692
            |.|.|:.|.:.|..|.|.||..:.:|:|||.|:.:|.:|....|.:..|..:....:     |..
 Frog    54 LLSAGLLLTLFFFIFTLRFRSNRIVKMSSPNLNLVTLIGSALTYISAFLFVVQEPNI-----SME 113

  Fly   693 TVCTARVYLLSAGFSLAFGSMFAKTYRVHRIFTRTGSVFKDK--MLQDIQLILLVGGLLLVDALL 755
            |:...|:.||..|.:|.||.:..|::|:||:||..   ..||  :::|:.|:.||.|||..|.||
 Frog   114 TIFQVRISLLYLGVTLVFGPLLGKSWRLHRVFTHR---VPDKRVIIKDVTLLSLVAGLLFADTLL 175

  Fly   756 VTLWVVTDPMERHLHNLTLEISATDRSVVYQPQV-EVCRSQHTQTWLSVLYAYKGLLLVVGVYMA 819
            :.:||::||:. ...:.:..|.|..|..:|.... :.|.|:::..|..:|..:|..||:.|.|:|
 Frog   176 LLMWVLSDPVV-CARSASASIKAAARGTLYSVTTQDFCASKYSDLWTGLLVGFKAALLIYGGYLA 239

  Fly   820 WETRHVKIPALNDSQYIGVSVYSVVITSAIVVVLANLISERVTLAFITITALILTSTTATLCLLF 884
            ..|.::..|.:|.|..|.:....|:..:..|.::.:...:...|.:.|.:..||..|||..||:|
 Frog   240 GLTNNISSPPVNQSLAIMIGNGLVMAGTGAVFLVTHFFHDWSNLVYATTSGSILVCTTAINCLIF 304

  Fly   885 IPKLHDIWARNDIIDPVIHS-MGLKMECNTRRFVVDDRRELQYRVEVQNRVYKKEIQALDAEIRK 948
            ||:|  :.:|....:.|..: |.......::.|......|..|.:..:|...:|.:...:|.|..
 Frog   305 IPQL--LQSRQFEEEQVQSTQMSKYFSSPSKSFRSMYSEEQIYHLLGENTSMRKLLSEKNAIIES 367

  Fly   949 LERLLESGLTTTSTTTSSSTSLLTGGGHLKPELTVTSGISQTPAASKNRTPSISGILPNLLLSVL 1013
            |:..:.:..........|..|..|      .|:|..|.:|.:..|.::.      :.|..:.::.
 Frog   368 LQEQVSNAKEKLMKLIKSECSFET------IEVTSLSVLSASTLAIQHH------VAPEHMKTIE 420

  Fly  1014 PPVIPRASWPSAEYMQIPMRRSVTFASQPQLEEACLPAQDLINLRLAHQQATEAKTGLINRLRGI 1078
            .|:   .|..:|::..:...............:|....:|. |::.:.::..|.
 Frog   421 EPL---DSVENADHEAVIKDTQEVDIKHDTKSDAFQSPKDQ-NIQESEEKPQEG----------- 470

  Fly  1079 FSRTTSSNKGSTASLADQKGLKAAFKSHMGLFTRLIPSSQTASCNAIYNNPNQDSIPSEASSHPN 1143
               :..:||.|..|::.|:.:..:             .|::.|...|.:..:... |.|||..
 Frog   471 ---SQCTNKPSGCSVSKQEDMSTS-------------DSRSVSFADIVSKSHHQH-PGEASER-- 516

  Fly  1144 GNHLKPIHRGSLTKSGTH--LDHLTKDPNFLPIPTISG--GEQGDQTLGGKYVKLLETKVNFQLP 1204
                            ||  |:.|::..|::....:..  .|...:|..|.:....:.:.:..:
 Frog   517 ----------------THDVLEQLSRKINYVSSEKLQEILQELSIETTCGHHSPKRQRRASHSV- 564

  Fly  1205 SNRRPSVVQQ----------PPSLRERVRG----------SPRFPHRILPPT-CSLSALAES--- 1245
             ||.|.:|..          .|.:..|.||          |..||:.:.|.| |.|:..|.:
 Frog   565 -NRDPGLVPSEGFRKMCVSLSPYMMRRRRGPVYSQRNQHPSHHFPNALPPQTWCLLNKEARNRCN 628

  Fly  1246 ------EDRP 1249
                  ::||
 Frog   629 GVKTTRDERP 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GABA-B-R3	NP_001245826.1	PBP1_GABAb_receptor	157..590	CDD:107361
		ANF_receptor	174..568	CDD:279440
		7tm_3	633..889	CDD:278433	80/259 (31%)
gpr156	XP_004919836.1	7tm_3	71..308	CDD:278433	75/246 (30%)
		VirE3	<311..398	CDD:284150	16/93 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000