Protein Alignment ds and si:ch73-233f7.1

DIOPT Version :10

• Sequence 1: NP_523446.2
• Gene: ds / 33245
• FlyBaseID: FBgn0284247
• Length: 3556
• Species: Drosophila melanogaster
• Sequence 2: NP_001352109.1
• Gene: si:ch73-233f7.1 / 100537710
• ZFINID: ZDB-GENE-141215-5
• Length: 1015
• Species: Danio rerio
• Alignment Length: 1039
• Identity: 269/1039 - (25%)
• Similarity: 427/1039 - (41%)
• Gaps: 213/1039 - (20%)

  Fly   830 ARYNYYVKEDIPRGTVVGSVIAASG-DVAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHE 893
            |:..|.:.|::..|..||::....| |||..|..|:.|.||....|..:...:|.:.:.:.:|.|
Zfish    31 AQIRYSIPEELEHGAFVGNIAEDLGLDVAKLSSRRFRIVSGARKQYLEVNLENGILFVNEKIDRE 95

  Fly   894 ---AKSQV-LLNIQATLGEP-PVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAA 953
               .:|.| .|::|..:..| .:|   :|.:|:.|||||||.|..|...:.:.|||..|:.....
Zfish    96 ELCEQSPVCFLHLQVVIENPLELY---RVEVEILDVNDNAPSFPWSEFNLEITESAAPGSRFPLE 157

  Fly   954 HAHDKDSGSSGQVTYSLVKESGKGLFAID-------ARSGHLILSQHLDYESSQRHTLIVTATDG 1011
            .|.|.|.||:...:|.|   |....|.:|       ::...|:|...||.|..:.|.:::||.||
Zfish   158 SAQDLDVGSNSLRSYLL---SANQHFVLDIQTRNDGSKFAELVLQSQLDREQQKMHEMVLTAVDG 219

  Fly  1012 GVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIV 1076
            |.|..|....|.|.|.|.|||.|||::..|.|::.|:......::::||:|||.|.|..|||..
Zfish   220 GSPLRSGTAQITVTVLDANDNVPVFDRSVYRVSLVENAPRGTLVLKLNATDLDEGANGEITYSF- 283

  Fly  1077 DAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIV 1141
                    :..:...|.:.|.:..:||.|.::..:|.|....|:|.|.|.|.|..|.....:|:|
Zfish   284 --------SGHAPLKVRELFSVDSHSGEIRVKGIVDYERASVYELYVQAKDKGPSAVAVHCKVLV 340

  Fly  1142 RVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSSFQVHP--- 1203
            .:||.|||.|:...:.....::|:...|:|:.|::..|.|.|||.|:... :|.|..||:|.
Zfish   341 DILDVNDNAPEVILTSVSTPVQEDAPPGTVIAVISVMDRDSGENGAVDCQ-IPGNVPFQLHSSFK 404

  Fly  1204 -----VTGEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDV 1263
                 ||.|.     ||||....|::.:.|||.|:|..|.|..:.:.|||:|||.|....|.. .
Zfish   405 NYYTLVTSEF-----LDRESVSEYNITLTARDLGSPPLSTRKTILVQVSDINDNPPRFIQPSY-T 463

  Fly  1264 VSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGL-----FSIDPTSGVIRTRVVL 1323
            |.|.|...||..:..|.|.|.|..|||.::|||::|:.   .|:     .||:..:|.|......
Zfish   464 VYVTENNAPGASICSVTAFDPDSNQNAYLSYSILEGQI---QGMPVSTYVSINSDNGNIYALRSF 525

  Fly  1324 DHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTS------SSLVFRVREDAALGH 1382
            |:|:...:::.|.|.|.|.||..:...:.|.|||.|||.|...|      |.....|......|:
Zfish   526 DYEQLRNFQIRVQAQDAGFPPLSSNVTVNVFVLDQNDNAPVILSPLPRNGSVATEMVPRSVDSGY 590

  Fly  1383 VVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNL-VVARLLDREVQ 1446
            :|..|:.::  ||..:||        |::|.:...|.   ...|.:..::|.: .:.|.:|::..
Zfish   591 LVAKITALD--ADAGQNS--------RLSYQVLQATD---PGLFSVALYTGEIRTIRRFVDKDAI 642

  Fly  1447 SEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATD 1511
            .: ||.|...|   :..|..|| ||.| :..|.|:.||...|..||.:|...|....::...:.
Zfish   643 RQ-RLVILVKD---NGQPPLSA-TVSI-ILSVVDSVPESLSDFGDLSLSPQPPSNLALYLIVSL- 700

  Fly  1512 ADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALD--- 1573
                                     ..:||..:.::....:::...|.:::..|.|  .:|.
Zfish   701 -------------------------STVSLIFLVAIIVLAAVKCYKDRDSLGGYAL--SSLSTAC 738

  Fly  1574 ------------QSSNVTERLQTSVTVRLRILDANDHAPH---------------------FVSP 1605
                        :.||:..::.|...|....::.|.:|.:                     |:.|
Zfish   739 CSFEPEPPAEVFKKSNLNLQISTGAKVPTNCMEVNSNAGNLSQAYCYKVCLTPESAKSDFMFLKP 803

  Fly  1606 -------NSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLT-YEITGGNGEGRFRINSQT 1662
                   |::.....:|.:|..:|...|            :||..| .|:...|.:.....| ||
Zfish   804 CSPGTPRNNAARGADNLALSSQSRCSSV------------NNGATTPNELKQANTDWALTKN-QT 855

  Fly  1663 GIIE----------LVKSLPPATEDVEKGGRFNLIIG--------AKD----------------- 1692
            ..::          ||:....|..:...|   .:..|        :|:
Zfish   856 SSVKSCNSINMDGTLVRKAMQAEPEHYMG---QMAAGQYWTWGTRSKEYRNQSPAGGVSQRAWTP 917

  Fly  1693 HGQPEPKKSSLNLHL--------IVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKS-LH 1747
            |..|:...:....||        ..|...|.||.:...||    :...|||...|:.:.:| ||
Zfish   918 HYTPQHNPTQNQHHLQQQQQQQATAQSHPNPPPDYQHNVY----IPGTPSGFCTLRPSHRSELH 977

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ds	NP_523446.2	CA	111..172	CDD:214520
		Cadherin_repeat	178..282	CDD:206637
		Cadherin_repeat	291..389	CDD:206637
		Cadherin_repeat	406..500	CDD:206637
		Cadherin_repeat	509..607	CDD:206637
		Cadherin_repeat	616..711	CDD:206637
		Cadherin_repeat	719..820	CDD:206637
		Cadherin_repeat	832..927	CDD:206637	29/100 (29%)
		Cadherin_repeat	937..1032	CDD:206637	32/101 (32%)
		Cadherin_repeat	1040..1149	CDD:206637	32/108 (30%)
		Cadherin_repeat	1158..1252	CDD:206637	34/101 (34%)
		Cadherin_repeat	1263..1361	CDD:206637	34/102 (33%)
		Cadherin_repeat	1369..1481	CDD:206637	26/112 (23%)
		Cadherin_repeat	1489..1598	CDD:206637	15/123 (12%)
		Cadherin_repeat	1614..1710	CDD:206637	22/139 (16%)
		Cadherin_repeat	1723..1843	CDD:206637	9/26 (35%)
		Cadherin_repeat	1853..1948	CDD:206637
		Cadherin_repeat	1957..2053	CDD:206637
		Cadherin_repeat	2061..2154	CDD:206637
		CA_like	2171..>2232	CDD:481204
		Cadherin_repeat	2326..2424	CDD:206637
		Cadherin_repeat	2434..2528	CDD:206637
		Cadherin_repeat	2549..2641	CDD:206637
		Cadherin_repeat	2652..2748	CDD:206637
		Cadherin_repeat	2758..2858	CDD:206637
		Cadherin_repeat	2866..2960	CDD:206637
		Cadherin_repeat	2985..3071	CDD:206637
si:ch73-233f7.1	NP_001352109.1	Cadherin_2	32..114	CDD:462413	22/81 (27%)
		Cadherin_repeat	139..240	CDD:206637	32/103 (31%)
		Cadherin_repeat	248..348	CDD:206637	32/108 (30%)
		Cadherin_repeat	361..453	CDD:206637	34/97 (35%)
		Cadherin_repeat	461..563	CDD:206637	34/105 (32%)
		Cadherin_repeat	582..670	CDD:206637	26/106 (25%)
		Cadherin_C_2	691..802	CDD:465139	13/138 (9%)
		Cadherin_tail	842..988	CDD:435046	27/144 (19%)