DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gsc and Poxn

DIOPT Version :9

Sequence 1:	NP_001137762.2	Gene:	Gsc / 33240	FlyBaseID:	FBgn0010323	Length:	473	Species:	Drosophila melanogaster
Sequence 2:	NP_001261016.1	Gene:	Poxn / 36741	FlyBaseID:	FBgn0003130	Length:	425	Species:	Drosophila melanogaster

Alignment Length:	226	Identity:	48/226 - (21%)
Similarity:	82/226 - (36%)	Gaps:	61/226 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 LNSQQCGYLGQRLQSVLQQQHAQHQQSQSQTPSSDDGSQSGVTILEEERRGGAAAASLFTIDSIL 170
            |..:..|.....::..||||..       ..|||.....|...||   |..|     |:| |.:.
  Fly    92 LKEENSGMFAWEIREQLQQQRV-------CDPSSVPSISSINRIL---RNSG-----LWT-DEMT 140

  Fly   171 GSRQQ--GGGTAPSQGSHISSNGNQNGLTSNGISLGLKRSGAESPASPNSNSSSSAAASP--IRP 231
            .|:|.  ....|.:..:|.:.:|..||.            |.::|..|.:.:..:.||:|  .|.
  Fly   141 SSQQNAAAAAAAAAAAAHQAGSGPSNGY------------GGQAPPPPVTVAPPTPAATPSIARY 193

  Fly   232 QRVPAMLQH--------------PGLHLGHLAAAAASGFAASPSDFLVAYPNFYPNYMHAAAVAH 282
            .:.||::.:              |.:..||     :.|...:.|...::|...:.:::...::.:
  Fly   194 AKPPALMMNSAGEMPIKPAPKMPPSMGHGH-----SHGLNPNVSGLDLSYSALHKHWLWNPSLLY 253

  Fly   283 VAAAQMQAHVSGAAAGLSGH------GHHPH 307
            ..    |||:...||...|.      |:.||
  Fly   254 YT----QAHIQAQAAASGGQFLPYAGGYLPH 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gsc	NP_001137762.2	Homeobox	343..396	CDD:278475
Poxn	NP_001261016.1	HTH	5..133	CDD:304362	13/50 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451035
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930