Protein Alignment: Gsc and Pitx1

• Sequence 1: NP_001137762.2
• Gene: Gsc
• FlyBaseID: FBgn0010323
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: NP_035227.1
• Gene: Pitx1
• MGIID: 107374
• Length: 315
• Species: Mus musculus
• Alignment Length: 237
• Identity: 68/238 (29%)
• Similarity: 91/238 (38%)
• Gaps: 75/238 (32%)

  Fly   229 IRPQRVPAMLQHPGLHLGHLAAAAASGFAASPSDFLVAYPNFYPNYMHAAAVAHVAAAQMQAHVS 293
            :||...|.....|..||..         ||.|.:.|       .|....::.|.:...:......
Mouse    17 LRPPPPPPHDMGPSFHLAR---------AADPREPL-------ENSASESSDADLPDKERGGEAK 65

  Fly   294 G---AAAGLSGHGHHPHHPHGHPHHPHLGAHHHGQHHLSHLGHGPPPKRKRRHRTIFTEEQLEQL 355
            |   ..||.:|.|.....|                         ...|::||.||.||.:||::|
Mouse    66 GPEDGGAGSAGCGGGAEDP-------------------------AKKKKQRRQRTHFTSQQLQEL 105

  Fly   356 EATFDKTHYPDVVLREQLALKVDLKEERVEVWFKNRRAKWRKQKREEQERLRKLQEEQCGSTTNG 420
            ||||.:..|||:.:||::|:..:|.|.||.||||||||||||::|.:|..|.|          .|
Mouse   106 EATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCK----------GG 160

  Fly   421 TTNSSSGTTSSTGNGSLTVKCPGSDHYSAQLVHIKSDPNGYS 462
            .....||...           |..|.|:|          |||
Mouse   161 YVPQFSGLVQ-----------PYEDVYAA----------GYS 181

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gsc	NP_001137762.2	Homeobox	343..396	CDD:278475	31/53 (58%)
Pitx1	NP_035227.1	Cnd2	48..>109	CDD:303063	20/86 (23%)
		Homeobox	94..146	CDD:278475	31/52 (60%)
		Interaction with PIT-1	151..280		13/63 (21%)
		Forkhead_N	204..>275	CDD:254796
		OAR	277..294	CDD:281777
		OAR. {ECO:0000255|PROSITE-ProRule:PRU00138}	281..294
		Nuclear localization signal. {ECO:0000255}	287..291

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R6207
TreeFam	0	0.000	Not matched by this tool.
	1	1.030