DRSC/TRiP Functional Genomics Resources

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Protein Alignment: Gsc and DMBX1

Sequence 1:NP_001137762.2 Gene:Gsc FlyBaseID:FBgn0010323 Length:473 Species:Drosophila melanogaster
Sequence 2:NP_671725.1 Gene:DMBX1 HGNCID:19026 Length:382 Species:Homo sapiens

Alignment Length:200 Identity:70/200 (35%)
Similarity:104/200 (52%) Gaps:34/200 (17%)


  Fly   298 GLSGHGHHPHHPHGHPHHPHLGAHHHGQH--------HLSHLG----------------HGPPPK 338
            |::|:..|..:.....::.|..|....||        |...|.                :|...:
Human     5 GVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLAGCTFQDIILEARYGSQHR 69

  Fly   339 RKRRHRTIFTEEQLEQLEATFDKTHYPDVVLREQLALKVDLKEERVEVWFKNRRAKWRKQKRE-E 402
            ::||.||.||.:|||.||.||.||||||||:||:||:..:|.|.||:|||||||||:||::|. :
Human    70 KQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQ 134

  Fly   403 QERLRKLQEEQCGSTTNGTTNSSSGTTSSTGNGSLTVKCPGSD-----HYS-AQLVHIKSDPNGY 461
            :|:|:| |:|..||  :|...:.:.|..:..:.....:.||||     |.| ::....:|.|...
Human   135 KEQLQK-QKEAEGS--HGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLSEQSASESAPEDQ 196

  Fly   462 SDADE 466
            .|.:|
Human   197 PDREE 201

Known Domains:


GeneSequenceDomainRegion External IDIdentity
GscNP_001137762.2 Homeobox 343..396 CDD:278475 36/53 (68%)
DMBX1NP_671725.1 Interaction with OTX2 and is required for repressor activity. {ECO:0000250|UniProtKB:Q91ZK4} 1..156 59/154 (38%)
Homeobox 74..127 CDD:278475 36/53 (68%)
Trypan_PARP <149..244 CDD:114603 12/53 (23%)
OAR. {ECO:0000255|PROSITE-ProRule:PRU00138} 359..372
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 avgDist Average_Evolutionary_Distance R6207
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.030

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