Protein Alignment: Gsc and DMBX1

• Sequence 1: NP_001137762.2
• Gene: Gsc
• FlyBaseID: FBgn0010323
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: NP_671725.1
• Gene: DMBX1
• HGNCID: 19026
• Length: 382
• Species: Homo sapiens
• Alignment Length: 200
• Identity: 70/200 (35%)
• Similarity: 104/200 (52%)
• Gaps: 34/200 (17%)

  Fly   298 GLSGHGHHPHHPHGHPHHPHLGAHHHGQH--------HLSHLG----------------HGPPPK 338
            |::|:..|..:.....::.|..|....||        |...|.                :|...:
Human     5 GVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLAGCTFQDIILEARYGSQHR 69

  Fly   339 RKRRHRTIFTEEQLEQLEATFDKTHYPDVVLREQLALKVDLKEERVEVWFKNRRAKWRKQKRE-E 402
            ::||.||.||.:|||.||.||.||||||||:||:||:..:|.|.||:|||||||||:||::|. :
Human    70 KQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQ 134

  Fly   403 QERLRKLQEEQCGSTTNGTTNSSSGTTSSTGNGSLTVKCPGSD-----HYS-AQLVHIKSDPNGY 461
            :|:|:| |:|..||  :|...:.:.|..:..:.....:.||||     |.| ::....:|.|...
Human   135 KEQLQK-QKEAEGS--HGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLSEQSASESAPEDQ 196

  Fly   462 SDADE 466
            .|.:|
Human   197 PDREE 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gsc	NP_001137762.2	Homeobox	343..396	CDD:278475	36/53 (68%)
DMBX1	NP_671725.1	Interaction with OTX2 and is required for repressor activity. {ECO:0000250|UniProtKB:Q91ZK4}	1..156		59/154 (38%)
		Homeobox	74..127	CDD:278475	36/53 (68%)
		Trypan_PARP	<149..244	CDD:114603	12/53 (23%)
		OAR. {ECO:0000255|PROSITE-ProRule:PRU00138}	359..372

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R6207
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.030