Protein Alignment Polr1B and NRPD2A

DIOPT Version :10

• Sequence 1: NP_476708.1
• Gene: Polr1B / 33210
• FlyBaseID: FBgn0003278
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: NP_189020.2
• Gene: NRPD2A / 821960
• AraportID: AT3G23780
• Length: 1172
• Species: Arabidopsis thaliana
• Alignment Length: 1185
• Identity: 316/1185 - (26%)
• Similarity: 509/1185 - (42%)
• Gaps: 189/1185 - (15%)

  Fly    42 SFDEMLTVGLDNSAKHMIPNHWLSPAGEKISMKVESIWIAKPKVPQDVIDVRTREIYPTDSRQLH 106
            ||.|||.....:..|.. .|.|     ...::|...:.:.||..   ..|.:..|..|..:|..:
plant    70 SFGEMLVEPSFDVVKKK-DNDW-----RYATVKFGEVTVEKPTF---FSDDKELEFLPWHARLQN 125

  Fly   107 VSYSGMCSVRLGWSV----------------NGVQKTPINMD-----LGEVPIMLRSKACNLGQA 150
            ::||....|.:...|                |.|:|..:::.     :|.:|:|::|..|...:
plant   126 MTYSARIKVNVQVEVFKNTVVKSDKFKTGQDNYVEKKILDVKKQDILIGSIPVMVKSILCKTSE- 189

  Fly   151 TPEEMVKHGEHDSEWGGIFVIRGNEK--IVRMLIMTRRNHPICVKRSSWKDRGQNFSDLGMLVQT 213
            ..:|..|.|:...:.||.|||:|.||  |.:..:.|:|   :.:..|.|....::.:.....:..
plant   190 KGKENCKKGDCAFDQGGYFVIKGAEKVFIAQEQMCTKR---LWISNSPWTVSFRSENKRNRFIVR 251

  Fly   214 VREDESSLSN-------VVHYLNNGTAKFMFSHVKRLSYVPVCLILKCL-------------MDY 258
            :.|:|.:...       .|::|:              :.:||.|:...|             .|.
plant   252 LSENEKAEDYKRREKVLTVYFLS--------------TEIPVWLLFFALGVSSDKEAMDLIAFDG 302

  Fly   259 TDEEIYNRLVQGYESDQYYVSCVQAMLREVQNENVYTHAQCKSFIGNLFRARFPEVPEWQPDDDV 323
            .|..|.|.|:    :..:....|....|...|...|...|.||       .:||      |.:.|
plant   303 DDASITNSLI----ASIHVADAVCEAFRCGNNALTYVEQQIKS-------TKFP------PAESV 350

  Fly   324 TDFILRERVMIHLDTYEDKFQLIVFMIQKLFQCAQGKYKVENVDSAMMQEVLLPGHLYQKYLSER 388
             |..|...:...|.:.:.|.:.:.:|::.|.....||.|.||.||...:.:.|.|.|.::.:...
plant   351 -DECLHLYLFPGLQSLKKKARFLGYMVKCLLNSYAGKRKCENRDSFRNKRIELAGELLEREIRVH 414

  Fly   389 VESWVSQVRRCLQKKLTSPDAL------VTSAVMTQCMRQAGGVGRAIESFLATGNIASRTGLGL 447
            :.....::.|.:||.|:....|      :.::|:|..:.:|...|.....|.....:
plant   415 LAHARRKMTRAMQKHLSGDGDLKPIEHYLDASVITNGLSRAFSTGAWSHPFRKMERV-------- 471

  Fly   448 MQNSGLVIMAENINRMRYMSHFRAIHRGSYFTTMRTTEARQLLPDAWGFICPVHTPDGTPCGLLN 512
               ||:|......|.::.:...|.. |.....|.:..:||...|..||.:|.:.||||..|||:.
plant   472 ---SGVVANLGRANPLQTLIDLRRT-RQQVLYTGKVGDARYPHPSHWGRVCFLSTPDGENCGLVK 532

  Fly   513 HLTLTCEISMRPDPKLVKAI----PKHLIDMGMMPLSNRRYLGEKLYVVFLDGKHLGHIHQSEAE 573
            :::|...:|.:....:|:.:    .:.|:|....||..:       :.|.|:|..:|..  :::|
plant   533 NMSLLGLVSTQSLESVVEKLFACGMEELMDDTCTPLFGK-------HKVLLNGDWVGLC--ADSE 588

  Fly   574 KIVDELRYGKIFGTLPQMMEIGFIPFKKNGQFPGLYIATGPARMMRP---VWNL-KWKR------ 628
            ..|.||:..:....||:.|||     |::.....:.|.|...|::||   |.|| |.|:
plant   589 SFVAELKSRRRQSELPREMEI-----KRDKDDNEVRIFTDAGRLLRPLLVVENLQKLKQEKPSQY 648

  Fly   629 ----------VEYIGTLEQLYMEIAIDAKEMY--PDFTTHLELAKTHFMSNLANLIPMPDYNQSP 681
                      :|.||..|:.....|...|::.  |...||.||..:..:.....::|..:::...
plant   649 PFDHLLDHGILELIGIEEEEDCNTAWGIKQLLKEPKIYTHCELDLSFLLGVSCAVVPFANHDHGR 713

  Fly   682 RNMYQCQMG-KQTMGTPCLNWPKQAANKL-YRLQTPGTPLFRPVHYDNIQLDDFAMGTNAIVAVI 744
            |.:||.|.. :|.:|....| |....:.| .:|..|..|||:.:..:.::.:....|.||||||.
plant   714 RVLYQSQKHCQQAIGFSSTN-PNIRCDTLSQQLFYPQKPLFKTLASECLKKEVLFNGQNAIVAVN 777

  Fly   745 SYTGYDMEDAMIINKAAYERGFAYGSIYKTKFLTLDKKSSYFARHPHMPELIK------------ 797
            .:.||:.||::::|||:.|||.......::....:|.|.|  .:...|.||::
plant   778 VHLGYNQEDSIVMNKASLERGMFRSEQIRSYKAEVDAKDS--EKRKKMDELVQFGKTHSKIGKVD 840

  Fly   798 HLDTDGLPHPGSKLSYGSPLY--CYFDGEVATYKVVKMDEKEDCIVESIRQLGSFDLSPKKMVAI 860
            .|:.||.|..|:.:|.|..:.  |...|  |.:. :|:...|..||:.: .|.|.| ..|...|:
plant   841 SLEDDGFPFIGANMSTGDIVIGRCTESG--ADHS-IKLKHTERGIVQKV-VLSSND-EGKNFAAV 900

  Fly   861 TLRVPRPATIGDKFASRAGQKGICSQKYPAEDLPFTESGLIPDIVFNPHGFPSRMTIAMMIETMA 925
            :||..|...:||||:|..||||:.......::.|||..|::||||.|||.||||.|...::|...
plant   901 SLRQVRSPCLGDKFSSMHGQKGVLGYLEEQQNFPFTIQGIVPDIVINPHAFPSRQTPGQLLEAAL 965

  Fly   926 GKG-----------AAIHGNVYDATPFRFSEENTAIDYFGKMLEAGGYNYYGTERLYSGVDGREM 979
            .||           ||.......||||    ....:....:.|...|::.:|.||:|:|..|..|
plant   966 SKGIACPIQKEGSSAAYTKLTRHATPF----STPGVTEITEQLHRAGFSRWGNERVYNGRSGEMM 1026

  Fly   980 TADIFFGVVHYQRLRHMVFDKWQVRSTGAVEARTHQPIKGRKRGGGVRFGEMERDALISHGAAFL 1044
            .:.||.|...||||.||..||.:.|:||.|...|.||:..|||.||::|||||||.||:|||:..
plant  1027 RSMIFMGPTFYQRLVHMSEDKVKFRNTGPVHPLTRQPVADRKRFGGIKFGEMERDCLIAHGASAN 1091

  Fly  1045 LQDRLFHNSDKTHTLVCHKCGSILAPLQRIVKRNETGGLSSQPDTCRLCGDNSSVSMIEIPFSFK 1109
            |.:|||..||.:...:|.||.:    ...:::|..:.|...:...||:|..:..|..:.:|:..|
plant  1092 LHERLFTLSDSSQMHICRKCKT----YANVIERTPSSGRKIRGPYCRVCVSSDHVVRVYVPYGAK 1152

  Fly  1110 YLVTELSSVNINARF 1124
            .|..||.|:.|...|
plant  1153 LLCQELFSMGITLNF 1167

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Polr1B	NP_476708.1	RNA_pol_B_RPB2	35..1125	CDD:238353	316/1185 (27%)
		RNA_pol_Rpa2_4	564..619	CDD:462028	14/54 (26%)
NRPD2A	NP_189020.2	RNA_pol_B_RPB2	48..1168	CDD:238353	316/1185 (27%)
		RNA_pol_Rpb2_4	574..635	CDD:428012	19/67 (28%)