Protein Alignment Polr1B and NRPD2B

DIOPT Version :10

• Sequence 1: NP_476708.1
• Gene: Polr1B / 33210
• FlyBaseID: FBgn0003278
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: NP_188437.2
• Gene: NRPD2B / 821334
• AraportID: AT3G18090
• Length: 1055
• Species: Arabidopsis thaliana
• Alignment Length: 1148
• Identity: 309/1148 - (26%)
• Similarity: 496/1148 - (43%)
• Gaps: 205/1148 - (17%)

  Fly    70 KISMKVE---SIWIAKPK--------VPQDVIDVRTREIYPTDSRQLHVSYSGMCSVRLGWSVNG 123
            |::.:||   .|.|...|        |.::::||:.::|.
plant    15 KVNAQVEVFKKIVIKHDKFKTGQDEYVEKEILDVKKQDIL------------------------- 54

  Fly   124 VQKTPINMDLGEVPIMLRSKACNLGQATPEEMVKHGEHDSEWGGIFVIRGNEK--IVRMLIMTRR 186
                     :|.:|:|::|..|...: ..:|..|.|....:.||.|||:|.||  |.:..:.|:|
plant    55 ---------IGSIPVMVKSVLCKTSE-KGKENCKKGNCAFDQGGYFVIKGAEKVFIAQEQMCTKR 109

  Fly   187 NHPICVKRSSWKDRGQNFSDLGMLVQTVREDESS-----LSNV--VHYLNNGTAKFMFSHVKRLS 244
               :.:..|.|....::.:.....:..:.|:|.:     :..|  |::|:              :
plant   110 ---LWISNSPWTVSFRSETKRNRFIVRLSENEKAEDYKIMEKVLTVYFLS--------------T 157

  Fly   245 YVPVCLILKCL-------------MDYTDEEIYNRLVQG-YESDQYYVSCVQAMLREVQNENVYT 295
            .:||.|:...|             .|..|..|.|.|:.. :|:|     .|....|...|...|.
plant   158 EIPVWLLFFALGVSSDKEAMDLIAFDGDDASITNSLIASIHEAD-----AVCEAFRCGNNALTYV 217

  Fly   296 HAQCKSFIGNLFRARFPEVPEWQPDDDVTDFILRERVMIHLDTYEDKFQLIVFMIQKLFQCAQGK 360
            ..|.||       .:||      |.:.|.| .||..:...|...:.|.:.:.:|::.|.....||
plant   218 EHQIKS-------TKFP------PAESVDD-CLRLYLFPCLQGLKKKARFLGYMVKCLLSAYAGK 268

  Fly   361 YKVENVDSAMMQEVLLPGHLYQKYLSERVESWVSQVRRCLQKKLTSPDAL------VTSAVMTQC 419
            .|.||.||...:.:.|.|.|.::.:...:.....::.|.:||:|:....|      :.::|:|..
plant   269 RKCENRDSFRNKRIELAGELLEREIRVHLAHARRKMTRAMQKQLSGDGDLKPIEHYLDASVITNG 333

  Fly   420 MRQAGGVGRAIESFLATGNIASRTGLGLMQNSGLVIMAENINRMRYMSHFRAIHRGSYFTTMRTT 484
            :.:|...|.....|.....:           ||:|......|.::.:...|.. |.....|.:..
plant   334 LNRAFSTGAWSHPFRKMERV-----------SGVVANLGRANPLQTLIDLRRT-RQQVLYTGKVG 386

  Fly   485 EARQLLPDAWGFICPVHTPDGTPCGLLNHLTLTCEISMRPDPKLVKAIPKHLIDMGMMPLSN--- 546
            :||...|..||.:|.:.||||..|||:.:::|...:|.:.    ::::.:.|...||..|.|
plant   387 DARHPHPSHWGRVCFLSTPDGENCGLVKNMSLLGLVSTQG----LESVVEMLFTCGMEELMNDTS 447

  Fly   547 RRYLGEKLYVVFLDGKHLGHIHQSEAEKIVDELRYGKIFGTLPQMMEIGFIPFKKNGQFPGLYIA 611
            ....|:  :.|.|:|..:|..  :::|..|.||:..:....||..|||     |::.....:.|.
plant   448 TPLCGK--HKVLLNGDWVGLC--ADSESFVGELKSRRRQSELPLEMEI-----KRDKDDNEVRIF 503

  Fly   612 TGPARMMRP---VWNL-KWKR----------------VEYIGTLEQLYMEIAIDAKEMY--PDFT 654
            |...|::||   |.|| |.|:                :|.||..|:.....|...|::.  |...
plant   504 TDAGRLLRPLLVVENLHKLKQDKPTQYPFKHLLDQGILELIGIEEEEDCTTAWGIKQLLKEPKNY 568

  Fly   655 THLELAKTHFMSNLANLIPMPDYNQSPRNMYQCQMG-KQTMGTPCLNWPKQAANKL-YRLQTPGT 717
            ||.||..:..:.....::|..:::...|.:||.|.. :|.:|....| |....:.| .:|..|..
plant   569 THCELDLSFLLGVSCAIVPFANHDHGKRVLYQSQKHCQQAIGFSSTN-PNIRCDTLSQQLFYPQK 632

  Fly   718 PLFRPVHYDNIQLDDFAMGTNAIVAVISYTGYDMEDAMIINKAAYERGFAYGSIYKTKFLTLDKK 782
            |||:.:..:.::.:....|.||||||..:.||:.||::::|||:.|||.......::....:|.|
plant   633 PLFKTLASECLEKEVLFNGQNAIVAVNVHLGYNQEDSIVMNKASLERGMFRSEQIRSYKAEVDTK 697

  Fly   783 SSYFARHPHMPELIK------------HLDTDGLPHPGSKLSYGSPLY--CYFDGEVATYKVVKM 833
            .|  .:...|.||::            .|:.||.|..|:.:|.|..:.  |...|  |.:. :|:
plant   698 DS--EKRKKMDELVQFGKTYSKIGKVDSLEDDGFPFIGANMSTGDIVIGRCTESG--ADHS-IKL 757

  Fly   834 DEKEDCIVESIRQLGSFDLSPKKMVAITLRVPRPATIGDKFASRAGQKGICSQKYPAEDLPFTES 898
            ...|..||:.: .|.|.| ..|...|::||..|...:||||:|..||||:.......::.|||..
plant   758 KHTERGIVQKV-VLSSND-EGKNFAAVSLRQVRSPCLGDKFSSMHGQKGVLGYLEEQQNFPFTIQ 820

  Fly   899 GLIPDIVFNPHGFPSRMTIAMMIETMAGKG------------AAIHGNVYDATPFRFSEENTAID 951
            |::||||.|||.||||.|...::|....||            ||.......||||    ....:.
plant   821 GIVPDIVINPHAFPSRQTPGQLLEAALSKGIACPIQKKEGSSAAYTKLTRHATPF----STPGVT 881

  Fly   952 YFGKMLEAGGYNYYGTERLYSGVDGREMTADIFFGVVHYQRLRHMVFDKWQVRSTGAVEARTHQP 1016
            ...:.|...|::.:|.||:|:|..|..|.:.||.|...||||.||..:|.:.|:||.|...|.||
plant   882 EITEQLHRAGFSRWGNERVYNGRSGEMMRSLIFMGPTFYQRLVHMSENKVKFRNTGPVHPLTRQP 946

  Fly  1017 IKGRKRGGGVRFGEMERDALISHGAAFLLQDRLFHNSDKTHTLVCHKCGSILAPLQRIVKRNETG 1081
            :..|||.||:||||||||.||:|||:..|.:|||..||.:...:|.||.:    ...:::|..:.
plant   947 VADRKRFGGIRFGEMERDCLIAHGASANLHERLFTLSDSSQMHICRKCKT----YANVIERTPSS 1007

  Fly  1082 GLSSQPDTCRLCGDNSSVSMIEIPFSFKYLVTELSSVNINARF 1124
            |...:...||:|..:..|..:.:|:..|.|..||.|:.|...|
plant  1008 GRKIRGPYCRVCASSDHVVRVYVPYGAKLLCQELFSMGITLNF 1050

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Polr1B	NP_476708.1	RNA_pol_B_RPB2	35..1125	CDD:238353	309/1148 (27%)
		RNA_pol_Rpa2_4	564..619	CDD:462028	14/54 (26%)
NRPD2B	NP_188437.2	RNA_pol_B_RPB2	3..1051	CDD:238353	309/1148 (27%)
		RNA_pol_Rpb2_4	456..517	CDD:428012	19/67 (28%)