Protein Alignment: RpI135 and rpoa-2

• Sequence 1: NP_476708.1
• Gene: RpI135
• FlyBaseID: FBgn0003278
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: NP_492476.1
• Gene: rpoa-2
• WormBaseID: WBGene00008781
• Length: 1127
• Species: Caenorhabditis elegans
• Alignment Length: 1124
• Identity: 482/1125 (43%)
• Similarity: 690/1125 (61%)
• Gaps: 56/1125 (5%)

  Fly    39 HVDSFDEMLTVGLDNSAKHMIPNHWLSPAGEKISMKVESIWIAKP------KVPQDVIDVRTREI 97
            ||||||.:::.|...:|:.:....:....|:.::||..|..:.||      |:..|     |..:
 Worm     9 HVDSFDFLVSKGCQFAAQAVPAEKFRLKNGDAVTMKFTSAQLHKPTLDTGAKLTSD-----TLPL 68

  Fly    98 YPTDSRQLHVSYSGMCSVRLGWSVNGVQKTPINMDLGEVPIMLRSKACNLGQATPEEMVKHGEHD 162
            .|.:.||..::|:|...|.:...|||.:...|.:.||:|||||||:.|:|...:.:|:|..||..
 Worm    69 LPAECRQRGLTYAGNLKVGIDVHVNGSRLDIIEIILGKVPIMLRSEGCHLRGMSRKELVVAGEEP 133

  Fly   163 SEWGGIFVIRGNEKIVRMLIMTRRNHPICVKRSSWKDRGQNFSDLGMLVQTVREDESSLSNVVHY 227
            .|.||.|::.|:||::|:||..|||.||.:.|.::|::|:.||:.|:::::|:|:.:::...:||
 Worm   134 IEKGGYFIVNGSEKVIRLLIANRRNFPIAIIRKTFKEKGKLFSEFGVMMRSVKENHTAVMMTLHY 198

  Fly   228 LNNGTAKFMFSHVKRLSYVPVCLILKCLMDYTDEEIYNRLVQGYESDQYYVSCVQAMLREVQNEN 292
            |:.||.:......:.:.|||:..|:|.|.|..|..|.....:|...||:|.||:..||.:.|.|.
 Worm   199 LDTGTMQLALQFRREIFYVPLMYIVKALTDKNDAVISAGFKRGRNQDQFYSSCILNMLAQCQEEE 263

  Fly   293 VYTHAQCKSFIGNLFRARFPE-VPEWQPDDDVTDFILRERVMIHLDTYEDKFQLIVFMIQKLFQC 356
            :.........||:.||....: |..|:.|.:...||:||.|:||||:.|:||..:.:|.|||...
 Worm   264 ILNQEAAIRAIGSRFRVAVSDRVAPWEDDLEAGRFIIRECVLIHLDSDEEKFHTLAYMTQKLIAL 328

  Fly   357 AQGKYKVENVDSAMMQEVLLPGHLYQKYLSERVESWVSQVRRCLQKKLTSPDALVTSAVMTQCM- 420
            .:|:...|..|:...||..:.||:....|.||:|:.:..|||.|:...:..|.::|||.:.:.:
 Worm   329 VKGECAPETPDNPQFQEASVSGHILLLILRERMENIIGMVRRKLEYMSSRKDFILTSAAILKALG 393

  Fly   421 -RQAGGVGRAIESFLATGNIASRTGLGLMQNSGLVIMAENINRMRYMSHFRAIHRGSYFTTMRTT 484
             ...|.:.|.:..||||||:.:|.||.|.|.||..::||.||::|::|||||||||::|..||||
 Worm   394 NHTGGEITRGMAYFLATGNLVTRVGLALQQESGFSVIAERINQLRFVSHFRAIHRGAFFMEMRTT 458

  Fly   485 EARQLLPDAWGFICPVHTPDGTPCGLLNHLTLTCEISMRPDPKLVKAIPKHLIDMGMM------- 542
            :.|:|.|:|||||||||||||.|||||||:|.:|.|.  .|......:|..|.::||.
 Worm   459 DVRKLRPEAWGFICPVHTPDGAPCGLLNHVTASCRIV--TDLSDNSNVPSLLAELGMYTHKTVAL 521

  Fly   543 --PLSNRRYLGEKLYVVFLDGKHLGHIHQSEAEKIVDELRYGKIF--GTLPQMMEIGFIPFK--- 600
              |       ||:||.|.::|:.||::..::|..|...||..|:.  ..:|...||..:...
 Worm   522 APP-------GEELYPVLMNGRFLGYVPITKAASIERYLRCAKVAKDARIPYTSEIALVRRSTDI 579

  Fly   601 KN--GQFPGLYIATGPARMMRPVWNLKWKRVEYIGTLEQLYMEIAIDAKEMYPDFTTHLELAKTH 663
            ||  .|:||:||.:...|::|||.||....||:|||.||:|:.:.:|.:|..|..|.|.||..:.
 Worm   580 KNIQTQYPGIYILSDAGRLIRPVRNLAMDAVEHIGTFEQVYLSVVLDPEEAEPGVTMHQELHPSC 644

  Fly   664 FMSNLANLIPMPDYNQSPRNMYQCQMGKQTMGTPCLNWPKQAANKLYRLQTPGTPLFRPVHYDNI 728
            ..|...||||.||:||||||:||||||||||||....|..:|.||:||||.|..|:.:...|:..
 Worm   645 LFSFAGNLIPFPDHNQSPRNVYQCQMGKQTMGTAVHAWHSRADNKMYRLQFPQQPMLKLEAYEKY 709

  Fly   729 QLDDFAMGTNAIVAVISYTGYDMEDAMIINKAAYERGFAYGSIYKTK---FLTLDKKSSYFARHP 790
            ::|::.:||||.|||||||||||||||.||||:|:||||:|::.|.:   .:|..::.:.|.|:|
 Worm   710 EMDEYPLGTNACVAVISYTGYDMEDAMTINKASYQRGFAHGTVIKVERINLVTERERKTIFYRNP 774

  Fly   791 HMPELIKHLDTDGLPHPGSKLSYGSPLYCYFDGEVATYKVVKMDEKED--CIVESIRQLGSFDLS 853
            .  |.||.:..||||.||.:.......|..|:.|...::..|....|.  |.:..|.:.|..| |
 Worm   775 R--EEIKTVGPDGLPIPGRRYFLDEVYYVTFNMETGDFRTHKFHYAEPAYCGLVRIVEQGEGD-S 836

  Fly   854 PKKMVAITLRVPRPATIGDKFASRAGQKGICSQKYPAEDLPFTESGLIPDIVFNPHGFPSRMTIA 918
            ..|...|..|:.|...||||||||.|||||.|..:|.|.|||:|:|::|||:||||||||||||.
 Worm   837 GAKHALIQWRIERNPIIGDKFASRHGQKGINSFLWPVESLPFSETGMVPDIIFNPHGFPSRMTIG 901

  Fly   919 MMIETMAGKGAAIHGNVYDATPFRFSEENTAIDYFGKMLEAGGYNYYGTERLYSGVDGREMTADI 983
            ||||:||||.||.||..|||:||.|:|:||||::||::|...||||||.|..|||||||:|...|
 Worm   902 MMIESMAGKAAATHGENYDASPFVFNEDNTAINHFGELLTKAGYNYYGNETFYSGVDGRQMEMQI 966

  Fly   984 FFGVVHYQRLRHMVFDKWQVRSTGAVEARTHQPIKGRKRGGGVRFGEMERDALISHGAAFLLQDR 1048
            |||:|:|||||||:.||:|||:||.::..||||:||||:|||:|||||||||:|:||.:|:||||
 Worm   967 FFGIVYYQRLRHMIADKFQVRATGPIDPITHQPVKGRKKGGGIRFGEMERDAIIAHGTSFVLQDR 1031

  Fly  1049 LFHNSDKTHTLVCHKCGSILAPLQRI--------VKRNETGGLS-SQPDTCRLCGDNSSVSMIEI 1104
            |.:.||:.....|.:|||:|:.|...        .||.:...|. ::...||.|..:..|.::::
 Worm  1032 LLNCSDRDVAYACRRCGSLLSVLMSSRAGSHLLKKKRKDDEPLDYTETQRCRTCDKDDQVFLLQV 1096

  Fly  1105 PFSFKYLVTELSSVNINAR 1123
            |..|:||..||:::|:..:
 Worm  1097 PRVFRYLTAELAAMNVKIK 1115

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RpI135	NP_476708.1	RpoB	34..1128	CDD:223163	482/1125 (43%)
		RNA_pol_B_RPB2	35..1125	CDD:238353	482/1125 (43%)
		RNA_pol_Rpa2_4	564..614	CDD:284335	17/57 (30%)
rpoa-2	NP_492476.1	RNA_pol_B_RPB2	5..1116	CDD:238353	482/1125 (43%)
		RpoB	9..1116	CDD:223163	482/1125 (43%)
		RNA_pol_Rpb2_2	<216..339	CDD:282427	44/123 (36%)
		RNA_pol_Rpa2_4	538..595	CDD:284335	17/57 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C56231026
eggNOG	1	0.900				E1_COG0085
Hieranoid	1	1.000
Homologene	1	1.000				H7133
Inparanoid	1	1.050	890	1.000	Inparanoid score	I198
Isobase	1	0.950		0	Normalized mean entropy	S774
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D42570at2759
OrthoFinder	1	1.000				FOG0003926
OrthoInspector	1	1.000				T477352
orthoMCL	1	0.900				OOG5_127929
Panther	1	1.100			LDO	PTHR20856
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R1173
TreeFam	1	0.960
	14	13.740