DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tbc1d15-17 and AT5G24390

DIOPT Version :9

Sequence 1:	NP_001259806.1	Gene:	Tbc1d15-17 / 33184	FlyBaseID:	FBgn0031233	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	NP_197827.1	Gene:	AT5G24390 / 832510	AraportID:	AT5G24390	Length:	528	Species:	Arabidopsis thaliana

Alignment Length:	521	Identity:	110/521 - (21%)
Similarity:	188/521 - (36%)	Gaps:	188/521 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   289 LSGSTNSACSSNGQSRGGSAEKSPADSELETLNAQDEKIVNNLPDRQRVERGHPLTETQWLEFQT 353
            ::.|:.::|||:....   ..|||.                   .|::.::  |||..:|....|
plant    33 VTSSSPASCSSSSDPH---RLKSPW-------------------SRRKGKK--PLTLRRWRRCFT 73

  Fly   354 PDGRISDSA--RIKELIFRGGVVQSLRPEVWKFLLNYYLWSDTHVERIERRKQKSIEYYNMKAQW 416
            |:|||.:..  .:|::..| |:..|:|.|||.|||....::.:..||...|..:...|..::.|.
plant    74 PEGRIRNGGVDLLKKVRTR-GIDPSIRSEVWPFLLGVCDFNSSEEERGATRTWRRKVYERLRRQC 137

  Fly   417 LAM--------------TTTQE-----------------ANFCGYRER----------------- 433
            ..:              .|||:                 .:.|...|.
plant   138 KRLQKQNSGTFKLNKINKTTQDDEHDSWSLAQDSESSCSDDACSVHESLISDKDNTEDIGYMSDV 202

  Fly   434 KCQIEKD-------------------------------------------VKRTDRSL------- 448
            .|.:::|                                           :.||....
plant   203 SCTLDRDYNGSRHLNSESSDSDSSDENDYVQVAPSCEGKDENSTSPSSIYISRTKEDFVTWQRII 267

  Fly   449 -----------------QFFAGEDNP---------------------NLTLLQGILMTYVMYNFD 475
                             |....|:..                     :...|..:|..|.:::.:
plant   268 RLDALRADTEWTPYSQSQALVSENRARRAAEAVGLKDYSYLEPSKIFHAARLVAVLEAYALHDPE 332

  Fly   476 LGYVQGMSDLLAPILEIQVNEVDTFWCFVGFMELVFTNFDIDQAGMKTQFAQIRRLIEFANAPLF 540
            :||.|||||||:|||.:..::.:.||||||||:....||.:|:.|:..|...:.::|:..::.|:
plant   333 IGYCQGMSDLLSPILSVIPDDYEAFWCFVGFMKKARQNFRVDEVGITRQLNIVSKIIKSKDSQLY 397

  Fly   541 NYMRSHDSDNMYFCFRWLLVWYKRELNSEDVLKLWECLWT--------------------RLPCP 585
            .::....:::.:|.:|.:||.::|||..|..|.|||.:|.                    |.|..
plant   398 KHLEKVKAEDCFFVYRMVLVMFRRELTLEQTLHLWEVIWADQAAIRAGMGKSSWSRRIKQRAPPT 462

  Fly   586 NFHLLFSVA--ILDQETRVIIDSQYEFTEILKHVNELSGNIDVQKTLQVAEGIYLQL--KGSETL 646
            ...||:.||  :| |..:|||:......|||:..:.:.|.:||.|.|..|..:.:.|  |...::
plant   463 EDLLLYVVAASVL-QRRKVIIEKYSSMEEILRECHNMVGKLDVWKLLDDAHDLIVTLHAKIEHSI 526

  Fly   647 P 647
            |
plant   527 P 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d15-17	NP_001259806.1	DUF3548	37..>191	CDD:192931
Tbc1d15-17	NP_001259806.1	TBC	369..598	CDD:214540	76/386 (20%)
AT5G24390	NP_197827.1	TBC	<322..482	CDD:214540	51/160 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1495285at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820