DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tbc1d15-17 and AT3G49350

DIOPT Version :9

Sequence 1:	NP_001259806.1	Gene:	Tbc1d15-17 / 33184	FlyBaseID:	FBgn0031233	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	NP_190504.2	Gene:	AT3G49350 / 824097	AraportID:	AT3G49350	Length:	539	Species:	Arabidopsis thaliana

Alignment Length:	525	Identity:	114/525 - (21%)
Similarity:	195/525 - (37%)	Gaps:	183/525 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   295 SACSSNGQSRGGSAEKSPADSELETLNAQDEKIVNNLP----DRQRV-------ERGHPLTETQW 348
            ::.|||..|...|...|.:.|....:.:....:.::.|    ||.|:       :|..||...||
plant    10 TSSSSNPSSPLSSPPSSSSSSSWIQIRSALFVVASSSPASCSDRPRLKSPWSRRKRKRPLRPQQW 74

  Fly   349 LEFQTPDGRISDSA--RIKELIFRGGVVQSLRPEVWKFLLNYYLWSDTHVERIERRKQKSIEYYN 411
            ..|.|||||:.:..  .:|::..| |:..|:|.|||.|||..|.::.:..||:..|.::..||..
plant    75 KRFFTPDGRLRNGGVDLLKKVRSR-GIEPSIRLEVWPFLLGLYGFNSSKEERVTIRNRRRKEYER 138

  Fly   412 MKAQ--------------------------WLAMTTTQEANFC---------------------G 429
            ::.|                          |..:..|..:  |                     |
plant   139 LRRQCKRLQKHNNGTRKLYNGSETIQDEYDWPRVQDTDSS--CSDEVVSARESLSSDEDITEDIG 201

  Fly   430 Y-RERKCQIEKDVKRTDRSL------------------------QFFAGEDNPNL---------- 459
            | .|..|.:|:|...:.|.:                        |.|.....|::
plant   202 YMSEVSCTVERDDGSSSRRITNATISTLNSESSDSDSSDESEVVQVFQSSATPDVNSTYPASSSI 266

  Fly   460 ---------------------------------------------------------------TL 461
                                                                           ..
plant   267 PRTEEDFVTWQRIIRLDAVRADSEWTSYSPSQAVISEDRACRAAEAVGLKDYNHLEPYKIFQAAR 331

  Fly   462 LQGILMTYVMYNFDLGYVQGMSDLLAPILEIQVNEVDTFWCFVGFMELVFTNFDIDQAGMKTQFA 526
            |..:|..|.:|:.|:||.|||||||:|||.:..::.:.||||||||:....||.:|:.|::.|..
plant   332 LVAVLEAYALYDPDIGYCQGMSDLLSPILSVIPDDHEVFWCFVGFMKKARHNFRLDEVGIRRQLN 396

  Fly   527 QIRRLIEFANAPLFNYMRSHDSDNMYFCFRWLLVWYKRELNSEDVLKLWECLWT----------- 580
            .:.::|:..::.|:.::....:::.:|.:|.::|.::|||..:..|.|||.:|.
plant   397 IVSKIIKSKDSQLYRHLEKLQAEDCFFVYRMVVVMFRRELTLDQTLCLWEVMWADQAAIRAGMGK 461

  Fly   581 --------RLPCPNFHLLFSVA--ILDQETRVIIDSQYEFTEILKHVNELSGNIDVQKTLQVAEG 635
                    |.|..:..:|:::|  :|.:..| ||:......|||:....::|.:||.|.|..|..
plant   462 SAWSRIRQRAPPTDDLVLYAIAASVLQRRKR-IIERYNSMDEILRECQSMAGQLDVWKLLDDAHD 525

  Fly   636 IYLQL 640
            :.:.|
plant   526 LVVTL 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d15-17	NP_001259806.1	DUF3548	37..>191	CDD:192931
Tbc1d15-17	NP_001259806.1	TBC	369..598	CDD:214540	78/394 (20%)
AT3G49350	NP_190504.2	TBC	<335..451	CDD:214540	42/115 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1495285at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820