DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Tbc1d15-17 and TBC1D3C

DIOPT Version :10

Sequence 1:NP_608503.1 Gene:Tbc1d15-17 / 33184 FlyBaseID:FBgn0031233 Length:715 Species:Drosophila melanogaster
Sequence 2:XP_006721967.1 Gene:TBC1D3C / 414060 HGNCID:24889 Length:610 Species:Homo sapiens


Alignment Length:268 Identity:62/268 - (23%)
Similarity:108/268 - (40%) Gaps:56/268 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   248 GILGNIPDYVQ-------PPFQRSPKSRPGVLISGDRQTSPDNYQIIGLSGSTNSACSSNGQSRG 305
            ||:.:.|.:..       |||   |...||:....:|..:...:......|...:.|||:     
Human    50 GIVQSCPSWESAPQEGPCPPF---PVPSPGLSPELERDRASPFWGSAPRLGPLQAPCSSS----- 106

  Fly   306 GSAEKSP-ADSELETLNAQDEKIVNNLPDRQRVERGHPLTETQWLEFQTPDGRISDSARIKELIF 369
             :....| :::||..|.|::.|.:     |:.:.|     :::|::......:...|.::.:..:
Human   107 -ALPGLPYSETELPPLTAREAKQI-----RREISR-----KSKWVDMLGDWEKYKSSRKLIDRAY 160

  Fly   370 RGGVVQSLRPEVWKFLLNYYLWSDTHVERIERRKQKSI-EYYNMKAQWLAMTTTQEANFCGYR-- 431
            : |:..::|..:|..|||           .|..|.|:. .|..||.:             |.|  
Human   161 K-GMPMNIRGPMWSVLLN-----------TEEMKLKNPGRYQIMKEK-------------GKRSS 200

  Fly   432 ERKCQIEKDVKRTDRSLQFFAGEDNPNLTLLQGILMTYVMYNFDLGYVQGMSDLLAPILEIQVNE 496
            |...:|::||..|.|...||..........|..||:.|..||.::||.:.:|.:.|..| :.:.|
Human   201 EHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFL-LYLPE 264

  Fly   497 VDTFWCFV 504
            .|.||..|
Human   265 EDAFWALV 272

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tbc1d15-17NP_608503.1 TBC 369..598 CDD:214540 38/139 (27%)
TBC1D3CXP_006721967.1 TBC 160..373 CDD:214540 38/139 (27%)
PHA03381 <417..>529 CDD:177618
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.