Protein Alignment Tbc1d15-17 and Tbc1d22b

DIOPT Version :10

• Sequence 1: NP_608503.1
• Gene: Tbc1d15-17 / 33184
• FlyBaseID: FBgn0031233
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_001401270.1
• Gene: Tbc1d22b / 381085
• MGIID: 2681867
• Length: 514
• Species: Mus musculus
• Alignment Length: 458
• Identity: 103/458 - (22%)
• Similarity: 191/458 - (41%)
• Gaps: 84/458 - (18%)

  Fly   255 DYVQPPFQ------------RSPKSRPGVLISGDRQTS-----PDNYQIIGLSG----STNSACS 298
            |:..||||            :..::...:.:..:|..|     |.||::|..|.    |.||...
Mouse    79 DFSSPPFQTLNSKVALATAAQVLENHSKLRVKPERSQSTTSDVPANYKVIKSSSDAQLSRNSILP 143

  Fly   299 SNGQSRGGSAEKSPADSELETLNAQDEKIVNNLPDRQRVERGHPLT---ETQWLEF-QTPDGRIS 359
            ......|.:..::|...:..........:|..:.| |......|:|   :|:..:| |......:
Mouse   144 LFQIPSGDTCLRNPLHKQQSLPLRPIIPLVARISD-QNASGAPPMTVREKTRLEKFRQLLSSHNT 207

  Fly   360 DSARIKELIFRGGVVQSLRPEVWKFLLNYYLWSDTHVERIERRK----QKSIEYYNMKAQWLAMT 420
            |...:::..: .||.:.:||..|: ||:.||.::|     ||||    :|..||:....|:.. :
Mouse   208 DLDELRKWSW-PGVPREVRPVTWR-LLSGYLPANT-----ERRKLTLQRKREEYFGFIEQYYD-S 264

  Fly   421 TTQEANFCGYRERKCQIEKDVKRTDRSLQFFAGEDNPNL-TLLQGILMTYVMYNFDLGYVQGMSD 484
            ..:|.:...||    ||..|:.||:..:..|   ..|.: .:.:.||..:.:.:...|||||::|
Mouse   265 RNEEHHQDTYR----QIHIDIPRTNPLIPLF---QQPLVQEIFERILFIWAIRHPASGYVQGIND 322

  Fly   485 LLAPILEIQVN-----------------------EVDTFWCFVGFMELVFTNFDIDQAGMKTQFA 526
            |:.|...:.::                       |.|:|||....::.:..|:...|.|::.:..
Mouse   323 LVTPFFVVFLSEYVEEDVENFDVTNLSQDMLRSIEADSFWCMSKLLDGIQDNYTFAQPGIQKKVK 387

  Fly   527 QIRRLIEFANAPLFNYMRSHDSDNMYFCFRWLLVWYKRELNSEDVLKLWECLWTRLPCP----NF 587
            .:..|:...:..:.::.|.::.:.:.|.|||:.....|||.....::||:...:.   |    :|
Mouse   388 ALEELVSRIDEQVHSHFRRYEVEYLQFAFRWMNNLLMRELPLRCTIRLWDTYQSE---PEGFSHF 449

  Fly   588 HLLFSVAILDQETRVIIDSQYEFTEILKHVNELS----GNIDVQKTLQVAEGIYLQLKGSETLPN 648
            ||....|.|.:..:.|:|.: :|..:|..:..|.    ||.::  .|.:||...|:...::. ||
Mouse   450 HLYVCAAFLIKWRKEILDEE-DFQGLLMLLQNLPTIHWGNEEI--GLLLAEAYRLKYMFADA-PN 510

  Fly   649 DIR 651
            ..|
Mouse   511 HYR 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d15-17	NP_608503.1	TBC	369..598	CDD:214540	63/260 (24%)
Tbc1d22b	NP_001401270.1	TBC	216..466	CDD:214540	63/267 (24%)