Protein Alignment Tbc1d15-17 and Tbc1d15

DIOPT Version :10

• Sequence 1: NP_608503.1
• Gene: Tbc1d15-17 / 33184
• FlyBaseID: FBgn0031233
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_001414160.1
• Gene: Tbc1d15 / 366896
• RGDID: 1307920
• Length: 688
• Species: Rattus norvegicus
• Alignment Length: 709
• Identity: 229/709 - (32%)
• Similarity: 347/709 - (48%)
• Gaps: 129/709 - (18%)

  Fly    38 TGNILFTHDGVLLKKASAE-HIADLNTSGSLSLVEYSRSIAEMPRRRLLLEWQPND------SIM 95
            :|.|::..:||.:..:|.: :..|...||.|.::|....:        :::|:|.|      ||:
  Rat     8 SGKIIYEQEGVYIHSSSGKANDQDSLISGILRVLEKDAEV--------IVDWRPLDDALDSSSIL 64

  Fly    96 IA-----------------------DDSQDQGDWALVDRISGRTRTTSECRAFNTRPIEPS--GG 135
            .|                       ..|..:.:|.:|..:|.:.:.       :|....||  .|
  Rat    65 YAGKDSSSVVEWTQAPKERAHRGSEHQSSYEAEWDMVTTVSFKKKP-------HTNGDAPSHRNG 122

  Fly   136 ATTRSRVMRAQLEDLSSVEVRHRG---QTIRFMRKGANGVHSEFFFQHGNADLFVRSM-RDQHLI 196
            .:..|.:.  .|.||.|::....|   ..:.|..|. :.|.....|..|::.|.:.|: :...|.
  Rat   123 KSKWSFLF--SLADLKSIKQSKEGMGWSYLVFCLKD-DVVLPALHFHQGDSKLLIESLGKYVVLC 184

  Fly   197 ENAETSRSGGEVYAILTTENQKLKKTFAEL----DIGQIKASQLPRES--WLPNKLAGILGNIPD 255
            |:::.||:     .::..:|:.|.::|..|    ..|.|:|..|.|..  |
  Rat   185 ESSQDSRT-----LLVNCQNKSLSQSFENLLDEPAYGLIQAGLLDRRKLLW-------------- 230

  Fly   256 YVQPPFQRSPKSRPGVLISGDRQTSPDNY--QIIGLSGSTNSACSSNGQSRGGSAEKSPADSELE 318
                            .|...|:...|.|  .::|.|..||....|...|...:.::.|  ||:.
  Rat   231 ----------------AIHHWRKIKKDPYTATMVGFSKVTNYIFDSLRGSDPSTHQRPP--SEMA 277

  Fly   319 ----------TLNAQDE---KIVN--NLPDRQRVERGHPLTETQWLEFQTPDGRISDSARIKELI 368
                      .:|.|:|   :::.  :|.:|..|:|..|::..:|.:....:||:.:...:|::|
  Rat   278 DFLSDAIPGLKINQQEEPGFEVITRIDLGERPVVQRREPVSLEEWTKSLDSEGRLLNVESMKQMI 342

  Fly   369 FRGGVVQSLRPEVWKFLLNYYLWSDTHVERIERRKQKSIEYYNMKAQWLAMTTTQEANFCGYRER 433
            ||||:..|||.:.|||||.|:.|..|..||.:.:|||:.||:.||.||.:::..||......|:.
  Rat   343 FRGGLSHSLRKQAWKFLLGYFPWDSTKEERTQLQKQKTDEYFRMKLQWKSVSEAQEKRNSRLRDY 407

  Fly   434 KCQIEKDVKRTDRSLQFFAGEDNPNLTLLQGILMTYVMYNFDLGYVQGMSDLLAPILEIQVNEVD 498
            :..|||||.||||:.:|:.|:|||.|.||..|||||.||:|||||||||||||:|:|.:..||||
  Rat   408 RSLIEKDVNRTDRTNKFYEGQDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPLLYVMENEVD 472

  Fly   499 TFWCFVGFMELVFTNFDIDQAGMKTQFAQIRRLIEFANAPLFNYMRSHDSDNMYFCFRWLLVWYK 563
            .||||..:|:.:..||:....|||||..|:..|:...::...:|:.|.||..:||||||||:.:|
  Rat   473 AFWCFASYMDQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFK 537

  Fly   564 RELNSEDVLKLWECLWTRLPCPNFHLLFSVAILDQETRVIIDSQYEFTEILKHVNELSGNIDVQK 628
            ||.:..|:|:|||.:||.|||.|||||...|||:.|.:.|::..|.|.|||||:||||..|||:.
  Rat   538 REFSFLDILRLWEVMWTELPCKNFHLLLCCAILESEKQQIMEKHYGFNEILKHINELSMKIDVED 602

  Fly   629 TLQVAEGIYLQLKGSETLPNDIRSIIGEPLLPAAAGEEIDGGMVDEEPTYSDDGFDELV 687
            .|..||.|.||:...:.||..:..|:               |:.|.|.|..|...||.|
  Rat   603 ILCKAEAISLQMAQCKELPQAVCEIL---------------GLQDSEVTTPDSDTDENV 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d15-17	NP_608503.1	TBC	369..598	CDD:214540	119/228 (52%)
Tbc1d15	NP_001414160.1	None