DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tbc1d15-17 and RN-tre

DIOPT Version :9

Sequence 1:	NP_001259806.1	Gene:	Tbc1d15-17 / 33184	FlyBaseID:	FBgn0031233	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	NP_652381.1	Gene:	RN-tre / 36554	FlyBaseID:	FBgn0020620	Length:	571	Species:	Drosophila melanogaster

Alignment Length:	308	Identity:	65/308 - (21%)
Similarity:	122/308 - (39%)	Gaps:	55/308 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   355 DGRISDSARIKELIFRGGVVQSLRPEVWKFLLNYYLWSDTHVERIERRKQKSIEYYNMKAQWLAM 419
            |.|:..:...:|:  ....::..|.:.|..:||.  |.... :::.:|..|.|........|..:
  Fly    57 DSRLPSTRDAQEV--HRNKIEMERDKKWMKMLNQ--WPPPQ-DKLHKRVYKGIPDRVRMVAWNKL 116

  Fly   420 TTTQEA--NFCG-----------YRERKCQIEKDVKRTDRSLQFFAGEDNPNLTLLQGILMTYVM 471
            ...|::  |..|           |.....||:.||.|..|....|....:.....|..:|..|.:
  Fly   117 LDIQQSINNNAGVYLRMLQLARKYSTETRQIDADVNRQFRDNLAFRERYSVKQCSLFNVLNAYSI 181

  Fly   472 YNFDLGYVQGMSDLLAPILEIQVNEVDTFWCFVGFMELVFTNFDIDQAGMKTQ-FAQIRRLIEFA 535
            ||.:|||.|||: .:|.:|.:.::|.:.||.    :..:.|:......|:..: |.::.|.|:..
  Fly   182 YNSELGYCQGMA-CVAGVLLLYLHEEEAFWA----LNTLITDQKYGMHGLFIEGFPKLTRFIDHH 241

  Fly   536 NAPLFNYMR-------SHDSDNMYFCFRWLLVWYKRELNSEDVLKLWECLWTRLPCPNFHLLFSV 593
            :..:...||       .|:.|.:.:..:|..|.:...:.....|::|:                :
  Fly   242 DRIMSKIMRKLHKHFTKHNVDALLYAIKWFFVVFVERVPFSLSLRVWD----------------I 290

  Fly   594 AILDQETRVIIDSQYEFTEILKHVNELSGNIDVQKTLQVAEGIYLQLK 641
            .:||.: |||:  ....|.:..|.:||....|:...::     |||::
  Fly   291 FMLDGD-RVIL--SMAITILYLHKDELLRLKDMDAIIE-----YLQVR 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d15-17	NP_001259806.1	DUF3548	37..>191	CDD:192931
Tbc1d15-17	NP_001259806.1	TBC	369..598	CDD:214540	50/249 (20%)
RN-tre	NP_652381.1	TBC	100..315	CDD:214540	51/238 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456561
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22957
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840