Protein Alignment Tbc1d15-17 and TBC1D16

DIOPT Version :9

• Sequence 1: NP_001259806.1
• Gene: Tbc1d15-17 / 33184
• FlyBaseID: FBgn0031233
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_609403.2
• Gene: TBC1D16 / 34431
• FlyBaseID: FBgn0032249
• Length: 702
• Species: Drosophila melanogaster
• Alignment Length: 681
• Identity: 172/681 - (25%)
• Similarity: 274/681 - (40%)
• Gaps: 143/681 - (20%)

  Fly    81 RRRLLLEWQPNDSI-----MIADDSQDQGDWALVDRISGRTRTTSECRAFNTRPIEPSGGATTRS 140
            |..|||.|.||.|:     :.|||.:.|                  |   |.|...|.    :|:
  Fly    77 RPTLLLTWIPNSSLCKYTNLNADDCRGQ------------------C---NPRSKSPD----SRN 116

  Fly   141 RVMRAQL-EDLSSVEVRHRGQTIRFMRKGANGVHSEFFFQHGNADLFVRSMRDQHL--------- 195
            ......: :.:...::|...:....|::..|.:......|..:.|.....:::..:
  Fly   117 GYCHVTIPQTIQERDIREEDENAADMQELKNELQPLLGGQAASIDDLTALLKNNPITSVNITISN 181

  Fly   196 --IENAETSRSGGEVYAILTTENQKLKKTFAELDIGQIKASQLPRESWLPNKLAGILGNIPDYVQ 258
              |||:..|:|...:  .:..::...........:|...|:..|:  |...:|.....|:
  Fly   182 PQIENSNISQSFNCI--TIRPDSNNCSDCTNGSGVGDGPATDNPK--WTTPELLAFKHNL----- 237

  Fly   259 PPFQRSPKSRPGVLISGDRQTSP--------DNYQIIGLSGSTNSACSSNGQSRGGSAEK----- 310
             .|..|..|.|     .|||.|.        |..|:..|....|....::||....|.|.
  Fly   238 -EFPDSGNSTP-----ADRQKSAMKCRHFSVDLSQMRSLRLFFNDDNCTSGQLVIASRESQYKIL 296

  Fly   311 ----SPADSELETLNAQDEKIVNNLPDRQRVERGHPLTETQWLEFQT-----------PD----- 355
                ...|...:.|: |....::|:..    |.|....:..:..|..           ||
  Fly   297 HFHYGGLDHLAQVLH-QWHCFLHNITS----ETGQDKFDLPYRHFMVCRPEVKKSEMHPDEGDVK 356

  Fly   356 ---------------GRISDSARIKELIFRGGVVQSLRPEVWKFLLNYYLWSDTHVERIERRKQK 405
                           |:|.|...:::.:|.||:.:|||..||.|||..|.:|.|..:|......|
  Fly   357 KITTNFFYGTLLNEKGQIEDDLLLRKCVFFGGLEKSLRKTVWPFLLKCYSFSSTFEDRAVLMDIK 421

  Fly   406 SIEYYNMKAQWL-AMTTTQEANFCGYRERKCQIEKDVKRTDRSLQFFAGEDNPNLTLLQGILMTY 469
            ..||..:..:.| :|:..|:.:|  ::..:..:||||.||||:..||.|:||||..:::.||:.:
  Fly   422 RQEYEEITRKRLYSMSPEQQIHF--WKTVQIVVEKDVVRTDRTNPFFCGDDNPNTEVMKNILLNF 484

  Fly   470 VMYNFDLGYVQGMSDLLAPIL-EIQVNEVDTFWCFVGFMELVF-----TNFDIDQAGMKTQFAQI 528
            .:||..:.|.|||||||||:| |:| ||.:|||||||.|:..|     |:.|:|.     ..:.:
  Fly   485 AVYNTGMSYSQGMSDLLAPVLCEVQ-NESETFWCFVGLMQRAFFVCTPTDRDVDH-----NLSYL 543

  Fly   529 RRLIEFANAPLFNYMRSH-DSDNMYFCFRWLLVWYKRELNSEDVLKLWECLWTRLPCPNFHLLFS 592
            |.||.......:.::..| ||..:.||.||||:.:|||.....|:::||..|:......|||...
  Fly   544 RELIRIMLPHFYKHLEQHNDSMELLFCHRWLLLCFKREFTEAVVIRMWEACWSNYLTDYFHLFLC 608

  Fly   593 VAILDQETRVIIDSQYEFTEILKHVNELSGNIDVQKTLQVAEGIYLQLKGSETLPNDIRSIIGEP 657
            :||:......::.......|:|.|.:.|:..:|.|..|:.|.|:..|.:....:|..:..:.
  Fly   609 LAIIAVYADDVVAQNLRPDEMLLHFSSLAMYMDGQLILRKARGLLHQYRQLPKIPCTLSGLC--- 670

  Fly   658 LLPAAAGEEIDGGMVDEE--PT-----YSDD 681
                   :....||.|.|  |.     :|||
  Fly   671 -------KRCGPGMWDSEHRPALECVGHSDD 694

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d15-17	NP_001259806.1	DUF3548	37..>191	CDD:192931	22/115 (19%)
		TBC	369..598	CDD:214540	92/236 (39%)
TBC1D16	NP_609403.2	TBC	387..618	CDD:214540	91/238 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456499
Domainoid	1	1.000	138	1.000	Domainoid score	I1049
eggNOG	1	0.900	-	-		E1_COG5210
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1495285at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22957
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850