Protein Alignment Tbc1d15-17 and tbc-12

DIOPT Version :9

• Sequence 1: NP_001259806.1
• Gene: Tbc1d15-17 / 33184
• FlyBaseID: FBgn0031233
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_508458.1
• Gene: tbc-12 / 180556
• WormBaseID: WBGene00044061
• Length: 614
• Species: Caenorhabditis elegans
• Alignment Length: 512
• Identity: 100/512 - (19%)
• Similarity: 173/512 - (33%)
• Gaps: 132/512 - (25%)

  Fly   232 KASQLPRESWLPNKLAGILGNIPDYVQPP------------------FQRSPKSRPGVLISGDRQ 278
            |.|.|.|.|           .:.|:.:||                  |.|:.:.:.|..:.|.|.
 Worm   147 KRSSLDRRS-----------ELSDFDEPPSKPETLSKSRFFNFPKNFFSRNKEEKHGWKMFGSRN 200

  Fly   279 TSPDNYQIIGL------SGSTNSACSSNGQSRG------GSAEKSPADSELETLNAQDEKIVNNL 331
            .........||      ||..:.:.......:.      ..|:|....:|.|.|.|:.|
 Worm   201 KQSGVMATTGLILEERPSGLPSKSADEAAHHKQMYLDILEQAKKKEQRAEKERLQAKAE------ 259

  Fly   332 PDRQRVERGHPLTETQWLEFQTPD-GRISDSARIKELIFRGGVVQSLRPEVWKFLLNYYL----- 390
              ::|:|.........|:|...|. ..:.||.|.:||.:: ||...:|.|:|...:...:
 Worm   260 --QKRLEEQTAAHCRVWVEQILPKWEEMKDSKRCRELWWQ-GVPAKVRGELWFLTIGNQIEITKE 321

  Fly   391 WSDTHVERIERRKQKSIEYYNMKAQWLAMTTTQEANFCGYRERK----CQIEKDVKRTDRSLQFF 451
            ..|..:::.|.:..|.:...|..:                .|||    .||..|..||..||..|
 Worm   322 LYDGLMDQAEEKIAKQLAEQNKNS----------------AERKETSVTQIHLDATRTFTSLGMF 370

  Fly   452 AGEDNPNLTLLQGILMTYVMYNFDLGYVQGMSDLLAPILEIQVNEVDTFWCFVGFMELVFTN--- 513
            . :|.|....|..:|..|.:...|:||||.|: .:|.:|.||   :|.:..|:.|..|:..:
 Worm   371 Q-KDGPYYDHLLKLLSAYAILRPDIGYVQSMT-FIAAVLLIQ---MDPYPAFISFANLLDRSLQS 430

  Fly   514 --FDIDQAGMKTQFAQIRRLIEFANAPLFNYMRSHDSDNMYFCFRWLLVWYKRELNSEDVLKLWE 576
              |.:.|..|...|....|.:|.....|..::...|.....:...|....|.:.|..:...::|:
 Worm   431 AFFGLKQPQMTEYFIAYDRYLEQELPALHQHLDKLDVRPDLYLIEWTFAMYAKSLPLDVTCRIWD 495

  Fly   577 CLWTRLPCPNFHLLFSVAI----LDQETRVIID-------------------------------- 605
            ..:.    .....||..|:    :.:...:.:|
 Worm   496 VYFR----DGEEFLFKAALGILRMYEPKLLTMDFDDCVEFLTKLPNTLTGAELFRNIEPFMRPYN 556

  Fly   606 -----SQYEFTEILKHVNELSGNIDVQKTLQVAEGIYLQLKGSETLPNDIRSIIGEP 657
                 |:..|::|.:.::|...........|:...:. :||.|::|...|:.::..|
 Worm   557 GESSRSKKRFSQIFQEIDERVNPGGTTARTQITHNVQ-ELKMSKSLSGFIKDLLSSP 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d15-17	NP_001259806.1	DUF3548	37..>191	CDD:192931
		TBC	369..598	CDD:214540	54/246 (22%)
tbc-12	NP_508458.1	TBC	295..521	CDD:214540	54/251 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810