DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tbc1d15-17 and AgaP_AGAP005738

DIOPT Version :9

Sequence 1:	NP_001259806.1	Gene:	Tbc1d15-17 / 33184	FlyBaseID:	FBgn0031233	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	XP_315752.4	Gene:	AgaP_AGAP005738 / 1276409	VectorBaseID:	AGAP005738	Length:	381	Species:	Anopheles gambiae

Alignment Length:	340	Identity:	71/340 - (20%)
Similarity:	120/340 - (35%)	Gaps:	116/340 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   341 HPLT---ETQWLEFQTPDGRISDSARIKELIFRGGVVQSLRPEVWKFLLNYYLWSDTHVERIERR 402
            |||:   |:.|..|                 ||...|          ||        .:::..||
Mosquito    91 HPLSDGPESNWSTF-----------------FRDNEV----------LL--------QIDKDVRR 120

  Fly   403 KQKSIEYYNMKAQW---------------LAMTTTQEANFCGYRERK----CQIEKDVKRTDRSL 448
            ....|.::....::               :|.||...||.    |||    .:|....||...|.
Mosquito   121 LCPDISFFQQATEFPCEFVKERERKLHVRVAPTTLSSANV----ERKGVGMTKINLITKRATESY 181

  Fly   449 QFFAGEDNPNLTLLQGILMTYVMYNFDLGYVQGMSDLLAPILEI----------QVNEVDTFWCF 503
            :........:..:::.||..|...|...||||||::::.||..:          :..|.|.|:||
Mosquito   182 EAMDAGQEAHWEVVERILFLYAKLNPGQGYVQGMNEIIGPIYYVFASDPHLEYRRYAEADCFFCF 246

  Fly   504 VGFM----ELVFTNFDIDQAGMKTQFAQIRRLIEFANAPLFNYMRSHDSDNMYFCFRWLLVWYKR 564
            ...|    :......|..:.|:|...|::..|:...:|.::..:|..:....|:.||||.:...:
Mosquito   247 TALMSEIRDFFIKTLDESEGGIKGMMAKLSNLLHEQDAEVWERLRDQELYPQYYSFRWLTLLLSQ 311

  Fly   565 ELNSEDVLKLWECLWTRLPCPNFHLLFSVAILDQETRVIIDSQYEF-------------TEILKH 616
            |....|||::|:.::..                       |.:|:|             .:||:
Mosquito   312 EFPLPDVLRIWDSVFAD-----------------------DKRYDFLIKICCAMILLLREQILE- 352

  Fly   617 VNELSGNIDVQKTLQ 631
             |:.:.|:   |.||
Mosquito   353 -NDFANNV---KLLQ 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d15-17	NP_001259806.1	DUF3548	37..>191	CDD:192931
Tbc1d15-17	NP_001259806.1	TBC	369..598	CDD:214540	55/261 (21%)
AgaP_AGAP005738	XP_315752.4	TBC	31..351	CDD:214540	64/321 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810