Protein Alignment CG42399 and AgaP_AGAP007923

DIOPT Version :9

• Sequence 1: NP_608498.3
• Gene: CG42399 / 33176
• FlyBaseID: FBgn0259818
• Length: 1655
• Species: Drosophila melanogaster
• Sequence 2: XP_001689043.1
• Gene: AgaP_AGAP007923 / 5668182
• VectorBaseID: AGAP007923
• Length: 960
• Species: Anopheles gambiae
• Alignment Length: 1063
• Identity: 366/1063 - (34%)
• Similarity: 523/1063 - (49%)
• Gaps: 189/1063 - (17%)

  Fly   672 GIGQLELALSSSSNLALVQPYLDSLLRTLLSSERHFEVSDLKRELLVNLISRLPLDNLEERTPQI 736
            |...:|.||.||.|||.|||||:|||||||||||:.:|.|.|..:||||:|||||:|||:|..||
Mosquito     2 GFCSIEEALKSSDNLAKVQPYLESLLRTLLSSERNLDVIDDKVRMLVNLVSRLPLENLEDRVGQI 66

  Fly   737 LSGLCRQGNAGANRVCKALMQRLPAGTIVAKLTSPEFLHAKSSKFRDHALQMSIFALMTFPGTCF 801
            ::||||||..|:|.|.||||||||...||.:|.|.:||||||||||::|||..:|||||||.|.|
Mosquito    67 MTGLCRQGGPGSNTVAKALMQRLPTAAIVQRLLSDDFLHAKSSKFRENALQTVLFALMTFPSTYF 131

  Fly   802 DISLLTTQAVYSLLNRKRRVRQAALEVLAVLADISSIKEVLTIVSETTDGVELGPMVLEATSVRL 866
            ||..|.::|..:.|:||:|||.|||:|||||..|||.|.||.::.........|..::.|...||
Mosquito   132 DIKTLISRATEAALDRKKRVRHAALDVLAVLGQISSPKLVLDVICAAVGTRSEGNHLITAVKARL 196

  Fly   867 SRLQLPIVTPDSGVLFVFNQTDPPGAR-----RFGADVDWIHQGEGSASPNTIKRRRMRAASSQR 926
            :|.|||.:.||..|.:...   .|..|     .||||||||..|.||||| |..|
Mosquito   197 ARKQLPFIGPDGSVEYAIK---VPSNRASSVIMFGADVDWIEAGSGSASP-TFNR---------- 247

  Fly   927 NVLGGAEAKNKNDPFPSFRQVNESVHRHSFHSPPETLDMASPINDFSQRLSFGAK-----TNGGS 986
                  ..:||   :|||:|.:.|....:.|               :|:...|.|     .|...
Mosquito   248 ------PGRNK---YPSFQQADRSRRSKARH---------------NQQPKAGGKFVRHTANSEW 288

  Fly   987 QSFIERRFLAKACSDTSMDGRSTDSTTTTCSSGSATDSFIQLTSRTGGRLAGPNSRFPTMNQHAD 1051
            |:|.:|..|...|||.:....:...:..:......:|.|:...|.....:|..:|.....|.|..
Mosquito   289 QTFTQRNILLLFCSDNNNSAANGAKSAMSVCKTITSDEFVGAPSEGMPPVALDSSTSSFNNHHHH 353

  Fly  1052 F-----------VNNFMRSMQRGSKSHSVERPNYPKVSYSIPKSQQMIRKKFQHKDSFTKLGD-E 1104
            .           .||...|...|.........|....|.:.|.:        .|:..|  ||: :
Mosquito   354 HHHDHHAASNGGANNRSNSASHGEHQSYYADSNMGTGSGTAPST--------PHRTRF--LGEHQ 408

  Fly  1105 PP-GQSIENNKFNESQRRKSGISTDHMESLDSKCADVIK--------------SVDTETEVNGMT 1154
            || |..|....:...:........|...|.||....:|.              :|..:....|..
Mosquito   409 PPAGAGINQESYIIHRDENYDSEQDERSSNDSTSTRIISNSILNFRERDRDRVTVGGDGPYPGAL 473

  Fly  1155 NGSPISASSTSYSQKSTASAKSSISQNEM-------GKRPFSSTGLWNDCKVEVLNREHN----- 1207
            :|.....|..|.|:..:.|:..||....:       |:...:|...:::..::..:...|
Mosquito   474 SGGSRPPSIPSVSRPQSVSSHKSIGSGVLKHQATPEGRTSRTSNASYSNASMKNASMGDNGSLKS 538

  Fly  1208 --------------PNEAFGELVVDAI----------KVQTESEPTAHEELLKLNGSLNSLHSKT 1248
                          ..|.:||.....|          :||.||:....::....|   :..|.|.
Mosquito   539 HRSFAGKTPGDDRADGEWYGERATTPIHSEMDGISSNQVQYESDYDEEDDEQVRN---HDRHLKP 600

  Fly  1249 ESIKTQLEETTPQLSRAQSVKSLLIEEDIESSNSFVVVEEVENELESSPAKGEEEVPLQEELATP 1313
            :|..|.....||.....|...|   .|::.|.|::   .:.:.|.|..    ||:..::||||.
Mosquito   601 KSPTTPKRYPTPSPRPLQGSYS---TEELSSHNAY---RQQDGEEEEE----EEDEEIEEELAI- 654

  Fly  1314 VKATKLENHTFGPKLVPTHDEIVIHSRSVSLDSLYGTRPASKQGSMDTSTSTAENTSQTGSQIGN 1378
                                                :||.|:          .::.|....|..:
Mosquito   655 ------------------------------------SRPRSR----------VQSASMGNLQHLD 673

  Fly  1379 TSVPAKAQHTPLKHKS--KTSYFLRAQRRISPSKQPIKMSQAE------LFPQNMVRFDRPREAL 1435
            ....|:....|:..|.  |..:.:|...:::|.|:.:...:|:      :|.:.:.||::|::||
Mosquito   674 RIEVAEQSPVPVSPKKILKKPFLVRRSSKVAPVKEVVSSVKAKNKLNEVIFQKTLRRFEKPKDAL 738

  Fly  1436 LKTFDQLDSSNWEVNVSGLKSMVRLIRYHAETLDNQMHMTCIQLTRSVRNLRSQVARASCQAAAE 1500
            ......|:|.|||.|:|||:..|||||:|.|.:|.|:|:..:.|.:.|||||||||||:|||:||
Mosquito   739 NNCLTHLESPNWEQNISGLQFFVRLIRHHPEVIDTQIHLLSVALAKQVRNLRSQVARAACQASAE 803

  Fly  1501 LFSLKSTSLQQECDDLVCALLHRTADTNRFLRADANRALESMVDHAQPQKILNILATKGAQHQNA 1565
            .|:.....|:.|.:|:...|||||||||:||||||.:|||:|.|:....|:::|::.|||.||||
Mosquito   804 FFATHRRCLEGEAEDIATHLLHRTADTNKFLRADATQALEAMCDNVSIPKVVHIISYKGATHQNA 868

  Fly  1566 LVRTTSAKLLFRLVERLGSDRIYAMGRESRDKFFVVGANLLLEGSLETRSYAKSLFRALSENHNY 1630
            :||||:||||.::|::|||::::|:.:|:|||..:.||:||||||||||:|.||:|:.|:::.||
Mosquito   869 VVRTTAAKLLNKIVQQLGSEKVFALPKETRDKLILTGAHLLLEGSLETRNYTKSMFKQLADHSNY 933

  Fly  1631 QRLLLEVIPPRTYRNVEKTLRSI 1653
            .::||||||||||||:||:|.||
Mosquito   934 SKVLLEVIPPRTYRNIEKSLNSI 956

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42399	NP_608498.3	CLASP_N	1433..1627	CDD:289144	105/193 (54%)
AgaP_AGAP007923	XP_001689043.1	CLASP_N	749..950	CDD:289144	115/200 (58%)
		HEAT repeat	818..844	CDD:293787	18/25 (72%)
		HEAT repeat	854..881	CDD:293787	16/26 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	512	1.000	Domainoid score	I1126
eggNOG	1	0.900	-	-		E1_KOG2933
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	791	1.000	Inparanoid score	I1458
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004509
OrthoInspector	1	1.000	-	-		otm50899
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X15729
TreeFam	1	0.960	-	-
	8	7.910