DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14618 and trm10

DIOPT Version :9

Sequence 1:	NP_608464.1	Gene:	CG14618 / 33134	FlyBaseID:	FBgn0031189	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_593764.1	Gene:	trm10 / 2543319	PomBaseID:	SPAC6B12.09	Length:	304	Species:	Schizosaccharomyces pombe

Alignment Length:	298	Identity:	88/298 - (29%)
Similarity:	147/298 - (49%)	Gaps:	31/298 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 TPGTPMSKNQLKKQRKLAEFAELRKLRRERE----REKKKQKRREAKELGLPVRTGPSRKELKKR 85
            |....:|||:.::|..|::.| |::|:|::|    |||:.:.|||.|.|         |||.:||
pombe    16 TSEADVSKNETQEQPVLSKSA-LKRLKRQQEWDAGREKRAEMRREKKRL---------RKEERKR 70

  Fly    86 QLADG------------GK---SGLSVAIDLDYDDLMQERDIVKCVKQCLRIYTINRRSPQPGNL 135
            ::..|            ||   |.:.:.:|..:||||.:::|....:|..|.::.||.:..|..|
pombe    71 KIEAGEVVKSQKKRIRLGKVVPSSIRIVLDCAFDDLMNDKEINSLCQQVTRCHSANRTALHPVEL 135

  Fly   136 HFTGIRRNGHIHESFKKNEGWENWHVQYYFDRGHTDIFE--HSQLVYLTCESDRVLDKLQPGCTY 198
            ..|.........:.|.......||.......:.:.:.||  ..:||||:.:||..:.:|.....|
pombe   136 FATNFGGRLKTRQDFVLKGQQNNWKRYNPTTKSYLEEFESQKEKLVYLSADSDNTITELDEDKIY 200

  Fly   199 VIGGLVDHNHFKGLCHSRATSAGLTTARLPLSEHVDMKTRAVLSTYHVFELLTKVAAGQDWTTAI 263
            :||.:||.|.:|.||.::|:..|:.||:||:.|::.:..|.:|:...|||:|:.....:||..|.
pombe   201 IIGAIVDKNRYKNLCQNKASEQGIKTAKLPIDEYIKITDRKILTVNQVFEILSLWLEYRDWEKAF 265

  Fly   264 LETIPMRKGAKAKITDKKEPNHCLEQQDEKQKQEAESD 301
            :|.||.|||...|..:..:.:.....|..:...|.|.:
pombe   266 MEVIPKRKGILLKSDESFDVSEDTRSQSNQSDSELEKE 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14618	NP_608464.1	tRNA_m1G_MT	105..271	CDD:280003	51/167 (31%)
trm10	NP_593764.1	tRNA_m1G_MT	105..273	CDD:280003	51/167 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	101	1.000	Domainoid score	I1810
eggNOG	1	0.900	-	-		E1_KOG2967
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6886
Inparanoid	1	1.050	134	1.000	Inparanoid score	I1407
OMA	1	1.010	-	-		QHG53860
OrthoFinder	1	1.000	-	-		FOG0004809
OrthoInspector	1	1.000	-	-		oto101970
orthoMCL	1	0.900	-	-		OOG6_102182
Panther	1	1.100	-	-	LDO	PTHR13563
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1545
SonicParanoid	1	1.000	-	-		X3391
TreeFam	0	0.000	Not matched by this tool.
	13	12.900