DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14618 and Trmt10a

DIOPT Version :9

Sequence 1:	NP_608464.1	Gene:	CG14618 / 33134	FlyBaseID:	FBgn0031189	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_001335125.1	Gene:	Trmt10a / 108943	MGIID:	1920421	Length:	330	Species:	Mus musculus

Alignment Length:	315	Identity:	110/315 - (34%)
Similarity:	163/315 - (51%)	Gaps:	28/315 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 EVTPAMLSLNNCP---GTTPG-------------TPMSKNQLKKQRKLAEFAELRKLRREREREK 58
            |:.||.:...|..   ||:.|             .|:||.||||..|..::.|.|:.|:|:.:||
Mouse     6 EMLPASIESTNVEEKLGTSDGEEERQEPRVDAGAEPISKRQLKKLMKQKQWEEQREQRKEKRKEK 70

  Fly    59 KKQKRREAKELGLPVRTGPSRKELKKRQLADGGKSGLSVAIDLDYDDLMQERDIVKCVKQCLRIY 123
            :|:|:.|.::|. ....|..||.:::    |..:|.|.:.||..:||||..:||.|..||..|.|
Mouse    71 RKRKKLERRQLE-SNSDGNDRKRVRR----DVARSSLRLVIDCSFDDLMVLKDIKKLHKQIQRCY 130

  Fly   124 TINRRSPQPGNLHFTGIRRNGHIHESFKKN-EGWENWHVQYYFDRGHTDIFEHSQLVYLTCESDR 187
            ..|||:..|...:.|.  ..|.:.::..:| :||.||...:.....::::.:...|||||.:|..
Mouse   131 AENRRASHPVQFYLTS--HGGQLKKNMDENDQGWVNWKDIHIKSEHYSELIKKEDLVYLTSDSPN 193

  Fly   188 VLDKLQPGCTYVIGGLVDHNHFKGLCHSRATSAGLTTARLPLSEHVDMKTRAVLSTYHVFELLTK 252
            ||..|.....|||||||||||.|||...:|||.|:..|:|||::.|.|.:|.||:..||||::.:
Mouse   194 VLKDLDESKAYVIGGLVDHNHHKGLTFKQATSYGIEHAQLPLADFVKMNSRKVLAVNHVFEIILE 258

  Fly   253 VAAGQDWTTAILETIPMRKGA----KAKITDKKEPNHCLEQQDEKQKQEAESDKP 303
            ....:||..|....:|.||||    ||..:..::.....|..|...:.|:..|.|
Mouse   259 FLETRDWQEAFFTILPQRKGAVPAHKACESSPQDHQSLPEGWDSASEGESCRDNP 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14618	NP_608464.1	tRNA_m1G_MT	105..271	CDD:280003	65/166 (39%)
Trmt10a	NP_001335125.1	Trm10euk_A	102..277	CDD:349974	69/176 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837927
Domainoid	1	1.000	122	1.000	Domainoid score	I5656
eggNOG	1	0.900	-	-		E1_KOG2967
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6886
Inparanoid	1	1.050	170	1.000	Inparanoid score	I4128
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53860
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004809
OrthoInspector	1	1.000	-	-		oto94983
orthoMCL	1	0.900	-	-		OOG6_102182
Panther	1	1.100	-	-	LDO	PTHR13563
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1545
SonicParanoid	1	1.000	-	-		X3391
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.830