Protein Alignment tty and Ttyh1

DIOPT Version :10

• Sequence 1: NP_542443.4
• Gene: tty / 33109
• FlyBaseID: FBgn0015558
• Length: 970
• Species: Drosophila melanogaster
• Sequence 2: NP_001425210.1
• Gene: Ttyh1 / 292597
• RGDID: 1310103
• Length: 501
• Species: Rattus norvegicus
• Alignment Length: 533
• Identity: 133/533 - (24%)
• Similarity: 239/533 - (44%)
• Gaps: 69/533 - (12%)

  Fly    11 YKVPVIAKLLHALPHYNITFHKINSTFRPNDEIYLESLGILGSVPAALLIVSLLGLLFYLMTRCC 75
            |:......|||.||..:.....:.|.|.|.|:.|.::|.::.::....|.:||:.:..||:..||
  Rat     7 YRPSAWVHLLHQLPRADFQLRPVPSGFAPRDQEYQQALLLVAALAGLGLGLSLIFIAVYLIRFCC 71

  Fly    76 DRKPRPAHS---------ITSLKVALSIVTVMCCAAIGLGLYGNDDLHNGLLEVLTAGRKVDNLV 131
            .|.|.|..:         :|...:|..:|.   ||.||:|.|||.:..:|:.::.:|.:..::.:
  Rat    72 CRPPEPPGAKSPPPGGGCVTWSCIAALLVG---CAGIGIGFYGNSETSDGVSQLSSALQHANHTL 133

  Fly   132 TTIRNQTHILENT--LTNRIRPQLVELADIFDQPVSNQTALSKLFVSLNIVQGNVTLATNAASDI 194
            :||.:.  :||..  |...:|.:|..|.::..:.|....|          .:|....|..||..:
  Rat   134 STIDDL--VLETVERLGEAVRTELTTLEEVLSERVELVAA----------TRGARRQAEAAAQHL 186

  Fly   195 RRPL--MGISMTHFLTRGDQW--ELIRWPGTVATLALLLVLCAVLLVGVARHSRCALILFSVCGL 255
            :...  .|:|::......|..  |..||...|..|.|:|::|...|:|:|:.|:..:::.:...|
  Rat   187 QGLAFWQGVSLSPVQVAEDVTFVEEYRWLAYVLLLLLVLLVCLFTLLGLAKQSKWLVVVMTAMSL 251

  Fly   256 LAVTGSWLMSGLYLSSSVAVGDLCISPADFLVSTAPRD--LPTNVLLHYTQCEPGHTNPFTQRLR 318
            |.:..||...||..:::|.:.|.|.:|..::::....:  :.:::|.:|..|....:|||.|||.
  Rat   252 LVLVLSWGSMGLEAATAVGLSDFCSNPDTYVLNLTQEETGISSDILNYYFLCNQAVSNPFQQRLT 316

  Fly   319 ESQNSLNNARSAMATVMKISLVLFKSSGLQPKLGAVNADLNSSERLLTQLTALVDCKAVHHNFLA 383
            .||.:|.:..|.:..:.:.:...|.::  |..|.::...||.:||...||.||:.|:::|.::.:
  Rat   317 LSQRALASIHSQLQGLEREASPQFPAA--QKPLLSLEETLNVTERSFHQLVALLHCRSLHKDYGS 379

  Fly   384 AARGLCEGGLLGLVLMLIASFIAAILLTIMVWVDSHTWIYIRKRNDYAQVDEPSYISHPAPQNHQ 448
            |.|||||..|.||:.:::.|.::|..|...:......|.....||..| :...|..|.|..|...
  Rat   380 ALRGLCEDALEGLLFLMLFSLLSAGALATTLCSLPRAWALFPPRNPSA-LCSGSLPSEPPCQCGL 443

  Fly   449 QMMNAARTLPRNHNGHFSPPVISGSHTLQHPSKRQQHEMMAHAHIQQNMRAMGT--HTLGRLPSH 511
            .::.....||...|                               .|::..:||  :.:..|||.
  Rat   444 PLLFGRVNLPVTWN-------------------------------VQSLLGLGTVWNRINLLPSS 477

  Fly   512 NHSPTHMTGPNNA 524
            :: ||......||
  Rat   478 SY-PTQERQKTNA 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tty	NP_542443.4	Tweety_N	10..429	CDD:143653	114/434 (26%)
Ttyh1	NP_001425210.1	None