Protein Alignment Rpt6 and Afg3l2

DIOPT Version :10

• Sequence 1: NP_608447.1
• Gene: Rpt6 / 33105
• FlyBaseID: FBgn0020369
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: NP_081406.1
• Gene: Afg3l2 / 69597
• MGIID: 1916847
• Length: 802
• Species: Mus musculus
• Alignment Length: 293
• Identity: 116/293 - (39%)
• Similarity: 169/293 - (57%)
• Gaps: 28/293 - (9%)

  Fly   121 TLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFDALGIAQPKGV 185
            |..|:|.:::             |..::.|.|.::...||.|.:.. :|:|:.:..||...|||.
Mouse   293 TTAKVLKDEI-------------DVKFKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGA 343

  Fly   186 LLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMDEI 250
            :|.|||||||||||:|.|......||.|||||.::.|:|.|...||:||.:||::||.|:|:|||
Mouse   344 ILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEI 408

  Fly   251 DSIGSSRIESGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDPALLRPGRIDRKIE 315
            |::|..|.....||.||.:.|:.:||.::|||..|.|:.::..|||.||||||||||||.||:|.
Mouse   409 DAVGRKRGRGNFGGQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIF 473

  Fly   316 FPPPNEEARLDILKIHSRKMNLTRGIN----LRKIAELMPGASGAEVKGVCTEAGMYALRERRVH 376
            ..||:.:.|..|.|:|.|.:.|...:.    .||:|.|.||.|||:|..||.||.:.|.|.....
Mouse   474 IGPPDIKGRASIFKVHLRPLKLDSALEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDA 538

  Fly   377 VTQEDFEMAV----------AKVMQKDSEKNMS 399
            :.::.||.|:          .:|:|.:.:|.::
Mouse   539 INEKHFEQAIERVIGGLEKKTQVLQPEEKKTVA 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpt6	NP_608447.1	PRK03992	23..399	CDD:179699	116/291 (40%)
Afg3l2	NP_081406.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	76..124
		HflB	156..746	CDD:440233	116/293 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	759..802