Protein Alignment Rpt6 and Katna1

DIOPT Version :10

• Sequence 1: NP_608447.1
• Gene: Rpt6 / 33105
• FlyBaseID: FBgn0020369
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: NP_001004217.2
• Gene: Katna1 / 292464
• RGDID: 1303062
• Length: 493
• Species: Rattus norvegicus
• Alignment Length: 499
• Identity: 145/499 - (29%)
• Similarity: 231/499 - (46%)
• Gaps: 113/499 - (22%)

  Fly     1 MTVTNRMEIESAYHKGEGFRS---YY---IQKIEELQLVVAEKHQNLRRLQAQRNELNAKVRMLR 59
            :.:|..:::...|.....:.|   ||   :.:|.:....|.:.|.: ::.|....|:|.:.:.::
  Rat     6 LMITENVKLAREYALLGNYDSAMVYYQGVLDQINKYLYSVKDTHLH-QKWQQVWQEINVEAKHVK 69

  Fly    60 EELQLLQ--------------EQGSYVGEVVK---PMDKKKV----------------------- 84
            |.::.|:              |..|..|||..   |::::.:
  Rat    70 EIMKTLESFKLDSTSLKAAQHELPSSEGEVWSLPVPVERRPLPGPRKRQSTQHSDPKPHSNRPGA 134

  Fly    85 LVKVHPEGKFVVDLDKNIDINDVTPNCRVALRNESYTLHKILPNKVDPLVSLMMVEKVPDSTY-- 147
            :|:.|......:..|:...:.......:...|.|.        ||:...|:.....|...:.|
  Rat   135 VVRAHRPSAQSLHSDRGKAVRSREKKEQSKGREEK--------NKLPAAVTEPEANKFDSTGYDK 191

  Fly   148 EMVGGLDKQI-------------------KEIKEVIELPVKHPELFDALGIAQP-KGVLLYGPPG 192
            ::|..|::.|                   |.::|.:.||:..||.|.  ||.:| ||||:.||||
  Rat   192 DLVEALERDIISQNPNVRWYDIADLVEAKKLLQEAVVLPMWMPEFFK--GIRRPWKGVLMVGPPG 254

  Fly   193 TGKTLLARAVAHHTEC--TFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGS 255
            |||||||:|||  |||  ||..||.|.|..|:.||..::||.||.|||.::|:.||:||||||.|
  Rat   255 TGKTLLAKAVA--TECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICS 317

  Fly   256 SRIESGSGGDSEV-QRTMLELLNQLDGF-------EATKNIKVIMATNRIDILDPALLRPGRIDR 312
            .|   |:..:.|. :|...|||.|:||.       :.:|.:.|:.|||....:|.||.|  |:::
  Rat   318 RR---GTSEEHEASRRVKAELLVQMDGVGGASENDDPSKMVMVLAATNFPWDIDEALRR--RLEK 377

  Fly   313 KIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRER---- 373
            :|..|.|:.:.|.::|:|..|::.|...:||..|||.|.|.|||::..||.:|.:.|:|.|
  Rat   378 RIYIPLPSAKGREELLRISLRELELADDVNLASIAENMEGYSGADITNVCRDASLMAMRRRIEGL 442

  Fly   374 -----------RVHV--TQEDFEMAVAKVMQKDSEKNMSIKKLW 404
                       .:|:  |.||||||:.||.:..|..::...:.|
  Rat   443 TPEEIRNLSREEMHMPTTMEDFEMALKKVSKSVSAADIERYEKW 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpt6	NP_608447.1	PRK03992	23..399	CDD:179699	140/467 (30%)
Katna1	NP_001004217.2	Kp60-NTD	7..74	CDD:439297	12/67 (18%)
		RPT1	134..474	CDD:440835	124/356 (35%)
		RecA-like_KTNA1	212..381	CDD:410930	78/177 (44%)