Protein Alignment Rpt6 and SHPK

DIOPT Version :10

• Sequence 1: NP_608447.1
• Gene: Rpt6 / 33105
• FlyBaseID: FBgn0020369
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: NP_037408.2
• Gene: SHPK / 23729
• HGNCID: 1492
• Length: 478
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 53/258 - (20%)
• Similarity: 85/258 - (32%)
• Gaps: 76/258 - (29%)

  Fly   115 LRNESYTLHKILPNKVDP-----LVSLMMVEKVPDST-------------YEMVGGLDKQIKEIK 161
            ||:..:.:| :||:..:|     ..|.|..| :|..|             |..:......:..|.
Human   217 LRSSGFPVH-LLPDIAEPGSVAGRTSHMWFE-IPKGTQVGVALGDLQASVYSCMAQRTDAVLNIS 279

  Fly   162 EVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVA---HHTECTFIRVSGSELVQKFI 223
            ..::|....|..|.......|...:.|. |...:|.|..|.:   .:...||:.:    |||...
Human   280 TSVQLAASMPSGFQPAQTPDPTAPVAYF-PYFNRTYLGVAASLNGGNVLATFVHM----LVQWMA 339

  Fly   224 GEG---------SRMVRELF------------VMAREHAPSIIFMDEIDSIGSSRIESGSGGDSE 267
            ..|         |||::...            |:...|.|     |::.|:  :||.|.......
Human   340 DLGLEVEESTVYSRMIQAAVQQRDTHLTITPTVLGERHLP-----DQLASV--TRISSSDLSLGH 397

  Fly   268 VQR-----------TMLELLNQLDGFEATKNIKVIMATNRIDILDPALLRPGRIDRKIEFPPP 319
            |.|           :||. :.||..:...:.:....|.:|.|:|...:.|        .||.|
Human   398 VTRALCRGIVQNLHSMLP-IQQLQEWGVERVMGSGSALSRNDVLKQEVQR--------AFPLP 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpt6	NP_608447.1	PRK03992	23..399	CDD:179699	53/258 (21%)
SHPK	NP_037408.2	ASKHA_NBD_FGGY_SHK	6..468	CDD:466796	53/258 (21%)