Protein Alignment Stt3A and Stt3b

DIOPT Version :10

• Sequence 1: NP_608425.1
• Gene: Stt3A / 33082
• FlyBaseID: FBgn0031149
• Length: 713
• Species: Drosophila melanogaster
• Sequence 2: NP_077184.2
• Gene: Stt3b / 68292
• MGIID: 1915542
• Length: 823
• Species: Mus musculus
• Alignment Length: 726
• Identity: 430/726 - (59%)
• Similarity: 533/726 - (73%)
• Gaps: 25/726 - (3%)

  Fly     7 GVARGLLTWDKQEHLVKLAILILAAVLSFATRLFSVLRFESVIHEFDPYFNYRTTRFLAEQGFYK 71
            |::.||......:.|:...||.||.:..|::|||:|:||||:||||||:||||:|..||..|||:
Mouse    54 GLSGGLSQPAGWQSLLSFTILFLAWLAGFSSRLFAVIRFESIIHEFDPWFNYRSTHHLASHGFYE 118

  Fly    72 FHNWFDDRAWYPLGRIIGGTIYPGLMLTSAALYRLMWLLNVTIDIRNVCVFLAPFFSSLTTLVTY 136
            |.||||:|||||||||:|||:|||||:|:..::.::..||:|:.||:|||||||.||.||::.|:
Mouse   119 FLNWFDERAWYPLGRIVGGTVYPGLMITAGLIHWILNTLNITVHIRDVCVFLAPTFSGLTSISTF 183

  Fly   137 ALTKEIHSTGAGLVAAALISIVPGYISRSVAGSYDNEGIAIFCMLFTYYLWIKAVKTGTIFWSAM 201
            .||:|:.:.||||:||..|:|||||||||||||:||||||||.:.||||||:|:||||::||:..
Mouse   184 LLTRELWNQGAGLLAACFIAIVPGYISRSVAGSFDNEGIAIFALQFTYYLWVKSVKTGSVFWTMC 248

  Fly   202 SALAYFYMVSSWGGYVFLINLIPLHVLALMITGRFSHRIYIAYSTLYCVGTILSMQISFVGFQPI 266
            ..|:||||||:||||||:||||||||..|::..|:|.|:||||||.|.||.||||||.|||||||
Mouse   249 CCLSYFYMVSAWGGYVFIINLIPLHVFVLLLMQRYSKRVYIAYSTFYIVGLILSMQIPFVGFQPI 313

  Fly   267 QSSEHMLALGTFGLCQIHAFVDYLRSRIPKDHFDLLFKTLVSSVLTVVFVVGTLLTLTGKVSPWT 331
            ::||||.|.|.|.|.|.:||:.|||.|:.|..|..||...||.....||:....||.||.::||:
Mouse   314 RTSEHMAAAGVFALLQAYAFLQYLRDRLTKQEFQTLFFLGVSLAAGAVFLSVIYLTYTGYIAPWS 378

  Fly   332 GRFYSLLDPSYAKNHIPIIASVSEHQPTSWSSFYFDLQILVFLFPAGLYFCFSKLTDSNIFIILY 396
            ||||||.|..|||.||||||||||||||:|.||:|||.|||..|||||:||...:.|..:|:.||
Mouse   379 GRFYSLWDTGYAKIHIPIIASVSEHQPTTWVSFFFDLHILVCTFPAGLWFCIKNINDERVFVALY 443

  Fly   397 GVTSIYFAGVMVRLMLVLAPVMCVLSGIAISHLLAKYI----KSVDAGSSSKQGVESKRQHKKLE 457
            .::::|||||||||||.|.||:|:||.||.|::...|:    |..:.........:.||....|.
Mouse   444 AISAVYFAGVMVRLMLTLTPVVCMLSAIAFSNVFEHYLGDDMKRENPPVEDSSDEDDKRNPGNLY 508

  Fly   458 QQTGGV--------KSEVAIG-----FVGVITLMLI-VYTLHCTWVTSEAYSSPSIVLSARSHDG 508
            .:.|.|        |.|..:|     .|.::.|||: ::.:|||||||.||||||:||::.:|||
Mouse   509 DKAGKVRKHVTEQEKPEEGLGPNIKSIVTMLMLMLLMMFAVHCTWVTSNAYSSPSVVLASYNHDG 573

  Fly   509 GRIIFDDFREAYYWLQMNTPEDARIMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMASS 573
            .|.|.|||||||:||:.||.|.||:||||||||||..|||||.|||||||||:||:.||:||:|:
Mouse   574 TRNILDDFREAYFWLRQNTDEHARVMSWWDYGYQIAGMANRTTLVDNNTWNNSHIALVGKAMSSN 638

  Fly   574 EEKAYEIMRELDVDYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGAH---IREKDYYAANGEF 635
            |..||:|||.||||||||||||:.|||.||||||||||||.    .|.|   |||.||:...|||
Mouse   639 ETAAYKIMRSLDVDYVLVIFGGVIGYSGDDINKFLWMVRIA----EGEHPKDIREGDYFTQQGEF 699

  Fly   636 RVDKEGSPTLLNCLMYKMCYYRFGQMYTEGGKAQGYDRVRAAEIGNKDFELDVMEEAYTTEHWLV 700
            ||||.|||||||||||||.|||||:|..:.....|:||.|.|||||||.:...:|||:|:|||||
Mouse   700 RVDKAGSPTLLNCLMYKMSYYRFGEMQLDFRTPPGFDRTRNAEIGNKDIKFKHLEEAFTSEHWLV 764

  Fly   701 RIYKVKDLPNR 711
            ||||||...||
Mouse   765 RIYKVKAPDNR 775

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Stt3A	NP_608425.1	STT3	21..495	CDD:396873	276/491 (56%)
Stt3b	NP_077184.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..58		1/3 (33%)
		STT3	68..560	CDD:396873	276/491 (56%)
		DXD motif 1. /evidence=ECO:0000250|UniProtKB:Q5HTX9	98..100		1/1 (100%)
		DXD motif 2. /evidence=ECO:0000250|UniProtKB:P39007	218..220		1/1 (100%)
		SVSE motif. /evidence=ECO:0000250|UniProtKB:Q5HTX9	399..402		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	487..526		6/38 (16%)
		WWDYG motif. /evidence=ECO:0000250|UniProtKB:P39007	601..605		3/3 (100%)
		Interacts with target acceptor peptide in protein substrate. /evidence=ECO:0000250|UniProtKB:B9KDD4	601..603		1/1 (100%)
		DK motif. /evidence=ECO:0000250|UniProtKB:P39007	668..675		6/6 (100%)