DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Stt3A and stt-3

DIOPT Version :9

Sequence 1:	NP_001259751.2	Gene:	Stt3A / 33082	FlyBaseID:	FBgn0031149	Length:	713	Species:	Drosophila melanogaster
Sequence 2:	NP_498362.1	Gene:	stt-3 / 175886	WormBaseID:	WBGene00020437	Length:	757	Species:	Caenorhabditis elegans

Alignment Length:	713	Identity:	406/713 - (56%)
Similarity:	522/713 - (73%)	Gaps:	32/713 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LVKLAILILAAVLSFATRLFSVLRFESVIHEFDPYFNYRTTRFLAEQGFYKFHNWFDDRAWYPLG 85
            |:.:.:|.||..:.||:|||:::||||:||||||:||||.|..:.:.|||||.||||:|||||||
Worm    19 LLTIVVLALAWFVGFASRLFAIVRFESIIHEFDPWFNYRATHHMVQHGFYKFLNWFDERAWYPLG 83

  Fly    86 RIIGGTIYPGLMLTSAALYRLMWLLNVTIDIRNVCVFLAPFFSSLTTLVTYALTKEIHSTGAGLV 150
            ||:|||:|||||:||..::.::..||..:.||.|||||||.||.||.:.||.||||:.|.||||.
Worm    84 RIVGGTVYPGLMVTSGLIHWILDSLNFHVHIREVCVFLAPTFSGLTAIATYLLTKELWSPGAGLF 148

  Fly   151 AAALISIVPGYISRSVAGSYDNEGIAIFCMLFTYYLWIKAVKTGTIFWSAMSALAYFYMVSSWGG 215
            ||..|:|.|||.||||||||||||||||.:.||||||:|::|||:|.|:::.||:||||||:|||
Worm   149 AACFIAISPGYTSRSVAGSYDNEGIAIFALQFTYYLWVKSLKTGSIMWASLCALSYFYMVSAWGG 213

  Fly   216 YVFLINLIPLHVLALMITGRFSHRIYIAYSTLYCVGTILSMQISFVGFQPIQSSEHMLALGTFGL 280
            |||:|||||||.|||:|.||:|.|::::|::.||:.||||||:.||||||:::||||.|.|.|||
Worm   214 YVFIINLIPLHALALIIMGRYSSRLFVSYTSFYCLATILSMQVPFVGFQPVRTSEHMPAFGVFGL 278

  Fly   281 CQIHAFVDYLRSRIPKDHFDLLF---KTLVSSVLTVVFVVGTLLTLTGKVSPWTGRFYSLLDPSY 342
            .||.|.:.|.|:||.:..|..||   .|::.::..||:..   |...|.|:|::||||||.|..|
Worm   279 LQIVALMHYARNRITRQQFMTLFVGGLTILGALSVVVYFA---LVWGGYVAPFSGRFYSLWDTGY 340

  Fly   343 AKNHIPIIASVSEHQPTSWSSFYFDLQILVFLFPAGLYFCFSKLTDSNIFIILYGVTSIYFAGVM 407
            ||.||||||||||||||:|.||:|||.|...:||.||::|..|:.|..:|||||.|:::||||||
Worm   341 AKIHIPIIASVSEHQPTTWVSFFFDLHITAAVFPVGLWYCIKKVNDERVFIILYAVSAVYFAGVM 405

  Fly   408 VRLMLVLAPVMCVLSGIAISHLLAKYIKSVDA--GSSSKQG--------------VESKRQHKKL 456
            |||||.|.|.:|||:||..|:...||:|..:.  .|||:.|              |:|:..:
Worm   406 VRLMLTLTPAVCVLAGIGFSYTFEKYLKDEETKERSSSQSGTTKDEKLYDKAAKNVKSRNAN--- 467

  Fly   457 EQQTGGVKSEVAIGFVGVITLMLIVYTLHCTWVTSEAYSSPSIVLSARSHDGGRIIFDDFREAYY 521
            :....||.|.|......::.:.|:::.:|.|:|||.|||.||:||.:.:::|.|||.|||||||:
Worm   468 DGDESGVSSNVRTIISIILVIFLLMFVVHATYVTSNAYSHPSVVLQSSTNNGDRIIMDDFREAYH 532

  Fly   522 WLQMNTPEDARIMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMASSEEKAYEIMRELDV 586
            ||:.||.:|||:||||||||||..|||||.|||||||||:||:.||:||:|:|..|||||.||||
Worm   533 WLRENTADDARVMSWWDYGYQIAGMANRTTLVDNNTWNNSHIALVGKAMSSNESAAYEIMTELDV 597

  Fly   587 DYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGAH---IREKDYYAANGEFRVDKEGSPTLLNC 648
            ||:||||||:.|||.||||||||||||.    :|.|   |||::|:.:.||:......|.|:|||
Worm   598 DYILVIFGGVIGYSGDDINKFLWMVRIA----QGEHPKDIREENYFTSTGEYSTGAGASETMLNC 658

  Fly   649 LMYKMCYYRFGQMYTEGGKAQGYDRVRAAEIGNKDFELDVMEEAYTTEHWLVRIYKVKDLPNR 711
            |||||.|||||:......:|.|:||.|...||.||..|:.:|||||||:|||||||.|.||||
Worm   659 LMYKMSYYRFGETRVGYNQAGGFDRTRGYVIGKKDITLEYIEEAYTTENWLVRIYKRKKLPNR 721

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Stt3A	NP_001259751.2	Stt3	19..712	CDD:224206	406/713 (57%)
Stt3A	NP_001259751.2	STT3	21..495	CDD:280649	266/492 (54%)
stt-3	NP_498362.1	STT3	19..506	CDD:280649	266/492 (54%)
stt-3	NP_498362.1	Stt3	22..751	CDD:224206	405/710 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62160
OrthoDB	1	1.010	-	-		D111618at33208
OrthoFinder	1	1.000	-	-		FOG0001875
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100521
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1409
SonicParanoid	1	1.000	-	-		X1235
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.760