Protein Alignment shakB and inx-1

DIOPT Version :10

• Sequence 1: NP_608410.2
• Gene: shakB / 33062
• FlyBaseID: FBgn0085387
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_741826.1
• Gene: inx-1 / 180968
• WormBaseID: WBGene00002123
• Length: 428
• Species: Caenorhabditis elegans
• Alignment Length: 380
• Identity: 96/380 - (25%)
• Similarity: 169/380 - (44%)
• Gaps: 55/380 - (14%)

  Fly   175 HVKIDSP-VFRLHTNATVILLITFSIAVTTRQYVGNPIDC---VHTRDIPEDVLNTYCWIHSTY- 234
            |.::|.. |.:|:.:.|..::..|:|.|:.:||||.||.|   ....|..|.....|||:.:||
 Worm    14 HPRVDDDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYY 78

  Fly   235 -TVVDAFMKKQGSEVPFPGVHNSQGRGPLTIKHTKYYQWVAFTLFFQAILFYTPRWLWKS---WE 295
             .:..||..:.|..               ..:...|||||.|.|..:|:.||.|..:|:.   |.
 Worm    79 LPLTSAFPLEYGDR---------------RARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWH 128

  Fly   296 GG---------KIHALIMDLD---------IGICSEAEKKQKKKLLLDYLWENLRYHNWWAYRYY 342
            .|         ...|.:||.|         .|...:|.:.|::...:..:....|:.|:....|.
 Worm   129 SGINVQSLTQMACDARMMDADARAATVQTIAGHMEDALEIQREVTDVSGMCVQKRWANYVTLLYV 193

  Fly   343 VCELLALINVIGQMFLMNRFFDGEFITFGLKVIDYMETDQEDRMDPMIYIFPRMTKCTFFKYGSS 407
            ..::|.|.||:.|:|::|.|...:.:.:|..::..:...:|..:...   |||:|.|. |:....
 Worm   194 FIKMLYLGNVVLQVFMLNSFLGTDNLFYGFHILRDLLNGREWEVSGN---FPRVTMCD-FEVRVL 254

  Fly   408 GEVEKHDAICILPLNVVNEKIYIFLWFWFILLTFLTLLTLIYRVVIIFSPRMRVYLFRMRFR--- 469
            |.|..|...|:|.:|:.||||::|||||:.::.|::.:::.:.::|.|.|...:...|...|
 Worm   255 GNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYLRATD 319

  Fly   470 -LVRRDAIEIIVRRSKMGDW-FLLYLLGENIDTVIFRDVVQDLANRLGHNQHHRV 522
             ...|.:::..|.:....|. |.:.::..:...::    ..:|...|.||.:.||
 Worm   320 LATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDIL----ATELIVALWHNFNDRV 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shakB	NP_608410.2	Innexin	180..513	CDD:459975	89/364 (24%)
inx-1	NP_741826.1	Innexin	20..365	CDD:459975	90/367 (25%)