Protein Alignment shakB and inx-3

DIOPT Version :10

• Sequence 1: NP_608410.2
• Gene: shakB / 33062
• FlyBaseID: FBgn0085387
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_509002.2
• Gene: inx-3 / 180866
• WormBaseID: WBGene00002125
• Length: 420
• Species: Caenorhabditis elegans
• Alignment Length: 396
• Identity: 108/396 - (27%)
• Similarity: 175/396 - (44%)
• Gaps: 69/396 - (17%)

  Fly   179 DSPVFRLHTNATVILLITFSIAVTTRQYVGNPIDCVHTRDIP---EDVLNTYCWIHSTYTVVDAF 240
            |..|.||....|..||..|||.|:.:||||:.|.|....:..   |.....||:|.:|:.:
 Worm    21 DDAVDRLSYVTTATLLAFFSIMVSCKQYVGSAIQCWMPMEFKGGWEQYAEDYCFIQNTFFI---- 81

  Fly   241 MKKQGSEVPFPGVHNSQGRGPLTIKHTKYYQWVAFTLFFQAILFYTPRWLWKSWE---GGKIHAL 302
              .:.||:| ..|.:.|.      ....|||||...|..||.:||.|.|:|.|..   |....::
 Worm    82 --PERSEIP-GDVEDRQK------AEIGYYQWVPIVLAIQAFMFYLPSWIWSSLYKQCGLDFPSV 137

  Fly   303 IMDLDIGICSEAEKKQK-KKLLLDYLWENL------RYHNWWAYRY-----------YVC-ELLA 348
            |.:.:.....::|.:.| ...|:|::.:.|      .|..::.||:           |:| :|:.
 Worm   138 ISEAEALRSQDSETRTKGVNKLVDFIGDILDTRSKNEYGRFYCYRFGKGLGSMTSMLYICIKLMY 202

  Fly   349 LINVIGQMFLMNRFFDGEFITFGLKVID--YMETDQEDRMDPMIYIFPRMTKCTFFKYGSSGEVE 411
            |.||..|..::|:|...|...:|.....  |...:.:|.     .:|||:|.|. |.......|.
 Worm   203 LANVFVQFIILNKFLGNETFLWGFHTFADLYAGREWQDS-----GVFPRVTLCD-FSVRKLANVH 261

  Fly   412 KHDAICILPLNVVNEKIYIFLWFWFI---LLTFLTLLTLIYRVVIIFSPRMRVYLFRMRFRLVR- 472
            ::...|:|.:|:.|||||:|:||||:   :.||:..|..|||  :.|......|:..:....|.
 Worm   262 RYTVQCVLMINMFNEKIYLFIWFWFVFVLITTFINTLCTIYR--LSFDSSRHNYIRSLLSGPVNN 324

  Fly   473 -RDAIEIIVRRSKMG---DWFLLY-LLGENIDTVIFRDVVQDLANRLGHN-QHHR---------- 521
             :|...:|...:..|   |..||. .:.::...::.:::.::|..:.|.| ||:|
 Worm   325 FKDEKAMIASFANNGLKQDGVLLMRFIDDHAGAMVTKEICEELFKKHGENLQHNRDFHHGHSTKS 389

  Fly   522 -VPGLK 526
             .|||:
 Worm   390 TSPGLE 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shakB	NP_608410.2	Innexin	180..513	CDD:459975	99/368 (27%)
inx-3	NP_509002.2	Innexin	22..370	CDD:459975	99/368 (27%)