Protein Alignment shakB and inx-8

DIOPT Version :10

• Sequence 1: NP_608410.2
• Gene: shakB / 33062
• FlyBaseID: FBgn0085387
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_502209.1
• Gene: inx-8 / 178101
• WormBaseID: WBGene00002130
• Length: 382
• Species: Caenorhabditis elegans
• Alignment Length: 338
• Identity: 86/338 - (25%)
• Similarity: 135/338 - (39%)
• Gaps: 61/338 - (18%)

  Fly   171 SSVSHV---KIDSPVFRLHTNATVILLITFSIAVTTRQYVGNPIDC----VHTRDIPEDVLNTYC 228
            |..||:   .||.....|....|..|.||.:|..:.:.|||:.::|    .::.|..|...| ||
 Worm     9 SLTSHLGITAIDDASDTLSCLITAFLFITAAILTSAKTYVGSAMECWLPQTYSGDWGEFAEN-YC 72

  Fly   229 WIHSTYTVVDAFMKKQGSEVPFPGVHNSQGRGPLTIKHTKYYQWVAFTLFFQAILFYTPRWLWKS 293
            ::..||     |..:|.|....|..|..:.|  ||     ||||.:..|....|.|..|::||:.
 Worm    73 FLKDTY-----FYPRQQSMTDIPMYHKERHR--LT-----YYQWSSMYLAVAGIAFMIPKFLWRL 125

  Fly   294 WEGGKIHALIMDLDIG--ICSEAEKKQKKKLL--------------LDYLWENLRYHNWWAYRYY 342
            .:......::...|..  |.:|.|.|:..|:.              ...|:..:|.:    ..|.
 Worm   126 SQSTTDMPVVYFCDTANEIKNETEDKRSAKIKEMARFMRTKITSVHTPSLFSFIRMY----MVYS 186

  Fly   343 VCELLALINVIGQMFLM--------NRFFDGEFITFGLKVIDYMETDQEDRMDPMIYIFPRMTKC 399
            |.::|.|:|.|.|..::        |.|:........|..|.:..|.          :|||:|.|
 Worm   187 VIKILYLVNAIAQFVIIAIFLGQKRNLFWGWTLFMNLLNGITWETTG----------LFPRVTFC 241

  Fly   400 TFFKYGSSGEVEKHDAICILPLNVVNEKIYIFLWFWFILLTFLTLLTLIYRVVIIFSPRMRVYLF 464
            .|.....:|........|::.:|..||||::|.|||.:.|.|.||:...|....|..|   .::.
 Worm   242 DFQVREMAGNNRDETVECVIGINEFNEKIFLFFWFWLVFLVFSTLIAHFYNAAQIVKP---YFIH 303

  Fly   465 RMRFRLVRRDAIE 477
            .:.|.:...|.::
 Worm   304 SLLFAIRDHDIVD 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shakB	NP_608410.2	Innexin	180..513	CDD:459975	81/326 (25%)
inx-8	NP_502209.1	Innexin	21..356	CDD:459975	81/326 (25%)