Protein Alignment Syx16 and TLG2

DIOPT Version :10

• Sequence 1: NP_523420.1
• Gene: Syx16 / 33034
• FlyBaseID: FBgn0031106
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_014624.1
• Gene: TLG2 / 854142
• SGDID: S000005378
• Length: 397
• Species: Saccharomyces cerevisiae
• Alignment Length: 348
• Identity: 86/348 - (24%)
• Similarity: 154/348 - (44%)
• Gaps: 78/348 - (22%)

  Fly    20 NRNHYDDRRGSDAERLLKHSVREAEEGLELQDDYGTPPAWLDKFEEAQYTMSKIKPKLDELGSLH 84
            |.:|....|.:| ||..||         |...| ..||.::|..::....:.:::...::|..::
Yeast    44 NMSHDISARLTD-ERKNKH---------ENHSD-ALPPIFIDIAQDVDDYLLEVRRLSEQLAKVY 97

  Fly    85 ARHLLRPAFDDQRDDECDIEVLSQIVSKLITSTH---RHIQCVRSSIGVGSKM----EQCLTVNA 142
            .::.| |.|:|:..||..||.||..|.:::...:   :.::.:.:|..|..|.    |..:..|.
Yeast    98 RKNSL-PGFEDKSHDEALIEDLSFKVIQMLQKCYAVMKRLKTIYNSQFVDGKQLSREELIILDNL 161

  Fly   143 VHCALLQLQELTVKFRASQNAYLLQLNSREERSQKYFDDGGGAGAGDVFTNVELGEQSAENFVDS 207
            ......::|..:.|||..||.||..||.         ||
Yeast   162 QKIYAEKIQTESNKFRVLQNNYLKFLNK---------DD-------------------------- 191

  Fly   208 FDNFLQPPAEGKSGNGYLFEDDEQA-----------IDDHFQRPPASRMTQQQLLLFEEENTRVA 261
                |:|.....|....|..|||:.           |:|:     :.|..|:|..|.:.......
Yeast   192 ----LKPIRNKASAENTLLLDDEEEEAAREKREGLDIEDY-----SKRTLQRQQQLHDTSAEAYL 247

  Fly   262 QHREQEVTKIVKSIYDLNDIFKDLGHMVQEQGTVLDRIDYNVEQTQTRVSEGLRQLHKAEMYQRK 326
            :.|::|:|::.:.:.:::.||:::..:|.:|||::||||||:|.|...:....::|:||..||::
Yeast   248 RERDEEITQLARGVLEVSTIFREMQDLVVDQGTIVDRIDYNLENTVVELKSADKELNKATHYQKR 312

  Fly   327 NRKMCVILVLA----AVTFFMLL 345
            .:|..|||:|.    |:.||::|
Yeast   313 TQKCKVILLLTLCVIALFFFVML 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syx16	NP_523420.1	COG5325	<212..343	CDD:227635	42/145 (29%)
		SNARE_syntaxin16	261..319	CDD:277198	18/57 (32%)
TLG2	NP_014624.1	COG5325	35..338	CDD:227635	86/348 (25%)