DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17065 and Amdhd2

DIOPT Version :9

Sequence 1:	NP_001162805.1	Gene:	CG17065 / 33026	FlyBaseID:	FBgn0031099	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	XP_036016505.1	Gene:	Amdhd2 / 245847	MGIID:	2443978	Length:	453	Species:	Mus musculus

Alignment Length:	452	Identity:	234/452 - (51%)
Similarity:	299/452 - (66%)	Gaps:	59/452 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 ASSQRLLQFTNCRLVRDHRIIHDDLWVRDGRIVNPEPVFFDERTKAHCRIDCGGAIIAPGYIDLQ 85
            |:...:|||||||::|...::.:|||||.|||::||.:||:||..|..:.||||.|:|||:||:|
Mouse     7 AAGAPVLQFTNCRILRGGTLLREDLWVRGGRILDPEKLFFEERRVADEQRDCGGRILAPGFIDVQ 71

  Fly    86 INGGYGVDFSYDTETIEEGVATVARGLVKSGVTSFCPTLVTSPSDSYH----------------- 133
            ||||:|||||..||.:..|||.|||.|:..|||||||||||||.:.||
Mouse    72 INGGFGVDFSKATEDVGSGVALVARRLLSHGVTSFCPTLVTSPPEVYHKAHSSSYKCARSSWALP 136

  Fly   134 ---------------------------TILPRIPAEV--PKGAGILGIHAEGPFINPQKKGAHPE 169
                                       .:||:||.:.  |.|||:||:|.|||||:.:|:|||||
Mouse   137 GRPCSCEPCPHAPSPPLCFPHAAGSTGKVLPQIPVKSGGPHGAGVLGVHLEGPFISREKRGAHPE 201

  Fly   170 HCIQTIDKRDHSNVTFRLPRLKGLSTLKETYGSLERIKIITLAPEKVTDPEVIGQLVERGITVAL 234
            ..:::.:.....:|.             .|||.|:.:.|:|||||.....|||..|..:||.|:|
Mouse   202 AYLRSFEANAFHDVL-------------ATYGPLDNVCIVTLAPELDRSHEVIQALTAQGIRVSL 253

  Fly   235 GHSMASLSDGERAVQQGATLITHLFNAMLPFHHRDPGLVGLLASDAVPHGRTVYFGIISDGVHTH 299
            |||:|.|...|.|||.|||.|||||||||||||||||:||||.||.:|.|..:::|:|:||:||:
Mouse   254 GHSVADLRAAEVAVQSGATFITHLFNAMLPFHHRDPGIVGLLTSDQLPPGHCIFYGMIADGIHTN 318

  Fly   300 PAALRIAYRTHPQGLILVTDAISALGLEEGVHHIGQLPLQVKQGKAFIAGTETLCGSIAPMDECV 364
            |||||||:|.|||||:|||||:.||||..|.|.:||..::|....|:||||:||.|||||||.||
Mouse   319 PAALRIAHRAHPQGLVLVTDAVPALGLGNGRHTLGQQEVEVDGLIAYIAGTKTLGGSIAPMDVCV 383

  Fly   365 RIFQKATDCSVVYAIEAATLHPAQCLKIEKQKGTLDFGSDADFVLLDDQLRVLSTWIAGVCV 426
            |.|.:||.|||..|:|||:|||||.|.:||.||:||||:|||||:|||.|.|.:|:|:|..|
Mouse   384 RHFLQATGCSVESALEAASLHPAQMLGLEKTKGSLDFGADADFVVLDDTLHVQATYISGELV 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17065	NP_001162805.1	NagA	27..423	CDD:238434	231/441 (52%)
CG17065	NP_001162805.1	HutI	38..431	CDD:224149	225/435 (52%)
Amdhd2	XP_036016505.1	NagA	13..442	CDD:238434	231/441 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841875
Domainoid	1	1.000	405	1.000	Domainoid score	I716
eggNOG	1	0.900	-	-		E1_COG1820
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9311
Inparanoid	1	1.050	465	1.000	Inparanoid score	I1531
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61032
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006638
OrthoInspector	1	1.000	-	-		oto93055
orthoMCL	1	0.900	-	-		OOG6_102909
Panther	1	1.100	-	-	LDO	PTHR11113
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4676
SonicParanoid	1	1.000	-	-		X4269
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.790