Protein Alignment CG17065 and Amdhd2

DIOPT Version :8

• Sequence 1: NP_001162805.1
• Gene: CG17065 / 33026
• FlyBaseID: FBgn0031099
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_766523.2
• Gene: Amdhd2 / 245847
• MGIID: 2443978
• Length: 409
• Species: Mus musculus
• Alignment Length: 408
• Identity: 234/409 (57%)
• Similarity: 299/409 (73%)
• Gaps: 15/409 (4%)

  Fly    21 ASSQRLLQFTNCRLVRDHRIIHDDLWVRDGRIVNPEPVFFDERTKAHCRIDCGGAIIAPGYIDLQ 85
            |:...:|||||||::|...::.:|||||.|||::||.:||:||..|..:.||||.|:|||:||:|
Mouse     7 AAGAPVLQFTNCRILRGGTLLREDLWVRGGRILDPEKLFFEERRVADEQRDCGGRILAPGFIDVQ 71

  Fly    86 INGGYGVDFSYDTETIEEGVATVARGLVKSGVTSFCPTLVTSPSDSYHTILPRIPAEV--PKGAG 148
            ||||:|||||..||.:..|||.|||.|:..|||||||||||||.:.||.:||:||.:.  |.|||
Mouse    72 INGGFGVDFSKATEDVGSGVALVARRLLSHGVTSFCPTLVTSPPEVYHKVLPQIPVKSGGPHGAG 136

  Fly   149 ILGIHAEGPFINPQKKGAHPEHCIQTIDKRDHSNVTFRLPRLKGLSTLKETYGSLERIKIITLAP 213
            :||:|.|||||:.:|:|||||..:::.:.....:|.             .|||.|:.:.|:||||
Mouse   137 VLGVHLEGPFISREKRGAHPEAYLRSFEANAFHDVL-------------ATYGPLDNVCIVTLAP 188

  Fly   214 EKVTDPEVIGQLVERGITVALGHSMASLSDGERAVQQGATLITHLFNAMLPFHHRDPGLVGLLAS 278
            |.....|||..|..:||.|:||||:|.|...|.|||.|||.|||||||||||||||||:||||.|
Mouse   189 ELDRSHEVIQALTAQGIRVSLGHSVADLRAAEVAVQSGATFITHLFNAMLPFHHRDPGIVGLLTS 253

  Fly   279 DAVPHGRTVYFGIISDGVHTHPAALRIAYRTHPQGLILVTDAISALGLEEGVHHIGQLPLQVKQG 343
            |.:|.|..:::|:|:||:||:|||||||:|.|||||:|||||:.||||..|.|.:||..::|...
Mouse   254 DQLPPGHCIFYGMIADGIHTNPAALRIAHRAHPQGLVLVTDAVPALGLGNGRHTLGQQEVEVDGL 318

  Fly   344 KAFIAGTETLCGSIAPMDECVRIFQKATDCSVVYAIEAATLHPAQCLKIEKQKGTLDFGSDADFV 408
            .|:||||:||.|||||||.|||.|.:||.|||..|:|||:|||||.|.:||.||:||||:|||||
Mouse   319 IAYIAGTKTLGGSIAPMDVCVRHFLQATGCSVESALEAASLHPAQMLGLEKTKGSLDFGADADFV 383

  Fly   409 LLDDQLRVLSTWIAGVCV 426
            :|||.|.|.:|:|:|..|
Mouse   384 VLDDTLHVQATYISGELV 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17065	NP_001162805.1	NagA	27..423	CDD:238434	231/398 (58%)
		HutI	38..431	CDD:224149	225/392 (57%)
Amdhd2	NP_766523.2	NagA	13..398	CDD:238434	231/398 (58%)
		HutI	31..401	CDD:224149	223/383 (58%)
		Substrate binding. {ECO:0000250|UniProtKB:P0AF18}	154..155		1/1 (100%)
		Substrate binding. {ECO:0000250|UniProtKB:P0AF18}	235..236		1/1 (100%)
		Substrate binding. {ECO:0000250|UniProtKB:P0AF18}	269..272		2/3 (67%)
		Substrate binding. {ECO:0000250|UniProtKB:P0AF18}	328..330		1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C248870332
eggNOG	1	0.900				E1_COG1820
Hieranoid	1	1.000
Homologene	1	1.000				H9311
Inparanoid	1	1.050	464	1.000	Inparanoid score	I1528
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0006015
OrthoInspector	1	1.000				T1084801
orthoMCL	1	0.900				OOG5_128970
Panther	1	1.100			LDO	PTHR11113
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R4676
TreeFam	1	0.960
	13	12.790